Índice completo — página 13 de 77

Estudos 1.201 a 1.300 de 7.640, ordenados do mais recente ao mais antigo — nesta página, publicações de 2022. Para buscar por termo ou combinar filtros, use o acervo com busca.

2022
Monoacylglycerol Lipase (MAGL) Inhibition Impedes the Osteosarcoma Progression by Regulating Epithelial Mesenchymal Transition
FavorávelEstudo LaboratorialCâncer Câncer — Ósseo Monoacilglicerol Lipase (MAGL)
2022
Mood, sleep and pain comorbidity outcomes in cannabis dependent patients: Findings from a nabiximols versus placebo randomised controlled trial
FavorávelEnsaio Clínico Duplo-CegoDor Dependência Química Efeitos Adversos da Cannabis Tetraidrocanabinol (THC)THC:CBD Farmacêutico+3
2022
Movement Disorders Secondary to Novel Antiseizure Medications in Pediatric Populations: A Systematic Review and Meta-analysis of Risk
InconclusivoMetanálise ClínicaEpilepsia Epilepsia — Síndrome de Dravet Epilepsia — Lennox-Gastaut CBD Farmacêutico
2022
Multimodal Correlates of Cannabis Use among U.S. Veterans with Bipolar Disorder: An Integrated Study of Clinical, Cognitive, and Functional Outcomes
InconclusivoEnsaio ClínicoTEPT Transtorno Bipolar
2022
Multinational Association of Supportive Care in Cancer (MASCC) expert opinion/consensus guidance on the use of cannabinoids for gastrointestinal symptoms in patients with cancer
InconclusivoMetanálise ClínicaCâncer Náusea e Vômito Anorexia (perda de apetite)THC Farmacêutico THC:CBD Farmacêutico+3
2022
Multiple regulation and targeting effects of borneol in the neurovascular unit in neurodegenerative diseases
FavorávelMetanáliseInflamação Doenças Neurodegenerativas
2022
Mutual Links between the Endocannabinoidome and the Gut Microbiome, with Special Reference to Companion Animals: A Nutritional Viewpoint
FavorávelMetanáliseAplicações Veterinárias Desequilíbrio do Microbioma Endocanabinoide (não especificado)Palmitoiletanolamida (PEA)+1
2022
N-acetyl cysteine in the treatment of cannabis use disorder: A systematic review of clinical trials
InconclusivoMetanálise ClínicaDependência Química Efeitos Adversos da Cannabis Dependência — Cannabis Canabinoide Sintético (não especificado)+6
2022
Nabiximols effect on blood pressure and heart rate in post-stroke patients of a randomized controlled study
InconclusivoEnsaio Clínico Duplo-CegoDoenças Cardiovasculares (DCV)AVC Hipertensão Arterial Tetraidrocanabinol (THC)THC:CBD Farmacêutico+1
2022
Naloxone Co-Dispensing with Opioids: a Cluster Randomized Pragmatic Trial
FavorávelEnsaio ClínicoDependência Química Dependência — Cannabis Dependência — Opioides+2
2022
Nationwide Trends in Hospitalizations and Outcomes of Pulmonary Circulation Disorders Among Patients With Cannabis Use Disorder in the United States
DesfavorávelMetanáliseDependência Química Inflamação Efeitos Adversos da Cannabis+9
2022
Nerolidol attenuates isoproterenol-induced acute myocardial infarction in rats
FavorávelEstudo em AnimaisDoenças Cardiovasculares (DCV)Infarto
2022
Nerolidol induced apoptosis via PI3K/JNK regulation through cell cycle arrest in MG-63 osteosarcoma cells
FavorávelEstudo LaboratorialCâncer Câncer — Ósseo
2022
Nerolidol: a potential approach in rheumatoid arthritis through reduction of TNF-α, IL-1β, IL-6, NF-kB, COX-2 and antioxidant effect in CFA-induced arthritic model
FavorávelEstudo em AnimaisArtrite Artrite — Reumatoide
2022
Neurological Benefits, Clinical Challenges, and Neuropathologic Promise of Medical Marijuana: A Systematic Review of Cannabinoid Effects in Multiple Sclerosis and Experimental Models of Demyelination
FavorávelMetanáliseEsclerose Múltipla Tetraidrocanabinol (THC)THC:CBD Farmacêutico+1
2022
Neuromodulation to Treat Substance Use Disorders in People With Schizophrenia and Other Psychoses: A Systematic Review
FavorávelMetanáliseDependência Química Dependência — Cannabis Psicose+6
2022
Neuroplastic alterations in cannabinoid receptors type 1 (CB1) in animal models of epileptic seizures
FavorávelMetanáliseEpilepsia Endocanabinoide (não especificado)
2022
Neuroprotection of Cannabidiol, Its Synthetic Derivatives and Combination Preparations against Microglia-Mediated Neuroinflammation in Neurological Disorders
FavorávelMetanáliseDor Inflamação Epilepsia Canabinoide Sintético (não especificado)Canabidiol Anormal (Abn-CBD)+7
2022
Neuroprotective effect of alpha-pinene is mediated by suppression of the TNF-α/NF-κB pathway in Alzheimer's disease rat model
FavorávelEstudo em AnimaisInflamação Ansiedade Disfunção Cognitiva Medicina Mente-Corpo+5
2022
Neuroprotective effects of synthetic borneol and natural borneol based on the neurovascular unit against cerebral ischaemic injury
FavorávelEstudo LaboratorialAVC
2022
Neuropsychological functioning and suicidal behaviours in patients with first-episode psychosis: A systematic review
DesfavorávelMetanáliseDependência Química Efeitos Adversos da Cannabis Dependência — Cannabis+4
2022
No protective benefits of low dose acute L-glutamine supplementation on small intestinal permeability, epithelial injury and bacterial translocation biomarkers in response to subclinical exertional-heat stress: A randomized cross-over trial
InconclusivoEnsaio ClínicoProteína Ligadora de Ácidos Graxos (FABP)
2022
Non-psychotropic Cannabis sativa L. phytocomplex modulates microglial inflammatory response through CB2 receptors-, endocannabinoids-, and NF-κB-mediated signaling
FavorávelEstudo LaboratorialInflamação Doenças Neurodegenerativas Endocanabinoide (não especificado)Outros Compostos Relacionados
2022
Non-psychotropic phytocannabinoid interactions with voltage-gated sodium channels: An update on cannabidiol and cannabigerol
FavorávelMetanáliseDor Dor — Crônica Dor — Aguda Canabigerol (CBG)
2022
Nonpharmacologic management of chronic pain in the United States’ Medicare population: a scoping review protocol
DesfavorávelMetanáliseDor Dor — Crônica
2022
Novel and emerging treatment options for acne vulgaris
FavorávelMetanáliseInflamação Acne Microbioma
2022
Novel Antidepressants in the Pipeline (Phase II and III): A Systematic Review of the US Clinical Trials Registry
FavorávelMetanáliseDepressão Ayahuasca
2022
NPS detection in prison: A systematic literature review of use, drug form, and analytical approaches
DesfavorávelMetanáliseDependência Química Efeitos Adversos da Cannabis Dependência — Cannabis Canabinoide Sintético (não especificado)Canabinoides Sintéticos 5F-x+4
2022
Nutritional Interventions to Improve Cachexia Outcomes in Cancer-A Systematic Review
InconclusivoMetanálise ClínicaCâncer Anorexia (perda de apetite)Caquexia Dieta Ômega-3
2022
Observational study of medical marijuana as a treatment for treatment-resistant epilepsies
InconclusivoMetanáliseEpilepsia Epilepsia — Lennox-Gastaut Tetraidrocanabinol (THC)
2022
Occupational contact urticaria to cannabis sativa
DesfavorávelMetanáliseDermatite de Contato Alérgica Alergia à Cannabis
2022
Olfactory Stimulation with Volatile Aroma Compounds of Basil ( Ocimum basilicum L.) Essential Oil and Linalool Ameliorates White Fat Accumulation and Dyslipidemia in Chronically Stressed Rats
FavorávelEstudo em AnimaisInflamação Doenças Cardiovasculares (DCV)Síndrome Metabólica Endocanabinoide (não especificado)+3
2022
Olivetolic acid, a cannabinoid precursor in Cannabis sativa, but not CBGA methyl ester exhibits a modest anticonvulsant effect in a mouse model of Dravet syndrome
FavorávelEstudo em AnimaisEpilepsia Epilepsia — Síndrome de Dravet Ácido Canabigerólico (CBG-a)
2022
Omega 3 Fatty Acid and Cannabidiol Prolong Lifespan and Ameliorates Brain Ischaemia in Mice Fed Chronic High Fat Diet
FavorávelEstudo em AnimaisInflamação Estresse Oxidativo Obesidade Ômega-3+2
2022
Opioid-sparing effect of cannabinoids for analgesia: an updated systematic review and meta-analysis of preclinical and clinical studies
FavorávelMetanáliseDependência Química Dependência — Opioides Anandamida (AEA)Endocanabinoide (não especificado)+10
2022
Opposite physiological and pathological mTORC1-mediated roles of the CB1 receptor in regulating renal tubular function
InconclusivoEstudo em AnimaisDiabetes Doença Renal Crônica
2022
Oral cannabidiol for prevention of acute and transient chemotherapy-induced peripheral neuropathy
FavorávelEnsaio ClínicoDor Dor — Polineuropatia Induzida por Medicamentos
2022
Oral capsules of tetra-hydro-cannabinol (THC), cannabidiol (CBD) and their combination in peripheral neuropathic pain treatment
DesfavorávelEnsaio Clínico Duplo-CegoDor Dor — Crônica Psicose+4
2022
Orchestration of the circadian clock and its association with Alzheimer's disease: Role of endocannabinoid signaling
FavorávelMetanáliseInflamação Doenças Neurodegenerativas Insônia e Distúrbios do Sono Endocanabinoide (não especificado)+1
2022
Over 1 year later: smokers' EVALI awareness, knowledge and perceived impact on e-cigarette interest
DesfavorávelMetanáliseEfeitos Adversos da Cannabis Lesão Pulmonar por Vaping (EVALI)
2022
Oxidative Stress and Autophagy Mediate Anti-Cancer Properties of Cannabis Derivatives in Human Oral Cancer Cells
FavorávelEstudo LaboratorialCâncer Inflamação Estresse Oxidativo Tetraidrocanabinol (THC)Delta-8-THC+1
2022
Oxytocin acts centrally in the brain to improve leaky gut through the vagus nerve and a cannabinoid signaling in rats
FavorávelEstudo em AnimaisAutismo Síndrome do Intestino Irritável Gastroparesia Endocanabinoide (não especificado)
2022
Pain response to cannabidiol in induced acute nociceptive pain, allodynia, and hyperalgesia by using a model mimicking acute pain in healthy adults in a randomized trial (CANAB I)
InconclusivoEnsaio Clínico Duplo-CegoDor Dor — Aguda CBD Farmacêutico
2022
Pain response to cannabidiol in opioid-induced hyperalgesia, acute nociceptive pain, and allodynia using a model mimicking acute pain in healthy adults in a randomized trial (CANAB II)
DesfavorávelEnsaio Clínico Duplo-CegoDor Inflamação Epilepsia CBD Farmacêutico+1
2022
Palmitoylethanolamide dampens neuroinflammation and anxiety-like behavior in obese mice
FavorávelEstudo em AnimaisInflamação Ansiedade Doenças Neurodegenerativas Palmitoiletanolamida (PEA)+3
2022
Palmitoylethanolamide Reduces Proinflammatory Markers in Unvaccinated Adults Recently Diagnosed with COVID-19: A Randomized Controlled Trial
FavorávelEnsaio Clínico Duplo-CegoCâncer Inflamação Doenças Cardiovasculares (DCV)2-Araquidonoilglicerol (2-AG)Palmitoiletanolamida (PEA)+6
2022
Palmitoylethanolamide-based nutraceutical Calmux® in preventive treatment of migraine
FavorávelEnsaio ClínicoDor Inflamação Enxaqueca Palmitoiletanolamida (PEA)
2022
Parkinson’s Disease and Dementia with Lewy Bodies, Patients Under Treatment with Standardized Extracts Enriched in Cannabidiol and Cannabigerol: Descriptive Observations in Preparation for a Phase 2a Clinical Trial
FavorávelMetanáliseDor Ansiedade Psicose Tetraidrocanabinol (THC)Canabigerol (CBG)+4
2022
Patterns of Use and Self-reported Effectiveness of Cannabis for Hyperemesis Gravidarum
FavorávelMetanáliseEfeitos Adversos da Cannabis Náusea e Vômito Gestação Tetraidrocanabinol (THC)+1
2022
PEGylated Lecithin-Chitosan Nanoparticle-Encapsulated Alphα-Terpineol for In Vitro Anticancer Effects
FavorávelEstudo LaboratorialCâncer
2022
Penile self-amputation due to cannabis-induced psychosis: a case report
DesfavorávelMetanáliseEfeitos Adversos da Cannabis Psicose
2022
Pentadecanoylcarnitine is a newly discovered endocannabinoid with pleiotropic activities relevant to supporting physical and mental health
FavorávelEstudo em AnimaisDor Inflamação Ansiedade Ácido Pentadecanoico (C15:0)Pentadecanoilcarnitina (PDC)+3
2022
Performance of urinary liver-type fatty acid-binding protein in diabetic nephropathy: A meta-analysis
FavorávelMetanálise ClínicaDiabetes Insuficiência Renal Doença Renal Crônica Proteína Ligadora de Ácidos Graxos (FABP)+1
2022
Peripheral Cannabinoid-1 Receptor Blockade Ameliorates Cystitis Severity
FavorávelEstudo em AnimaisCistite Endocanabinoide (não especificado)Canabinoide Sintético (não especificado)
2022
Persistent Diarrhea and Eosinophilic Esophagitis Resulting From Chronic Cannabidiol Usage for Refractory Epilepsy
DesfavorávelMetanáliseDor Epilepsia Epilepsia — Síndrome de Dravet+4
2022
Pharmacokinetic Evaluation of a Cannabidiol Supplement in Horses
FavorávelEstudo em AnimaisAplicações Veterinárias
2022
Pharmacokinetic Profile of ∆9-Tetrahydrocannabinol, Cannabidiol and Metabolites in Blood following Vaporization and Oral Ingestion of Cannabidiol Products
InconclusivoEnsaio Clínico Duplo-CegoCBD Farmacêutico
2022
Pharmacokinetics of cannabichromene in a medical cannabis product also containing cannabidiol and Δ9-tetrahydrocannabinol: a pilot study
FavorávelEnsaio Clínico Duplo-CegoDor Inflamação Depressão Tetraidrocanabinol (THC)Monoacilglicerol Lipase (MAGL)+3
2022
Pharmacokinetics, Safety, and Synovial Fluid Concentrations of Single- and Multiple-Dose Oral Administration of 1 and 3 mg/kg Cannabidiol in Horses
FavorávelEstudo em AnimaisAplicações Veterinárias
2022
Pharmacokinetics, Safety, and Tolerability of a Medicinal Cannabis Formulation in Patients with Chronic Non-cancer Pain on Long-Term High Dose Opioid Analgesia: A Pilot Study
FavorávelEnsaio ClínicoDor Dor — Crônica Dependência — Opioides Tetraidrocanabinol (THC)
2022
Pharmacological Activation of GPR55 Improved Cognitive Impairment Induced by Lipopolysaccharide in Mice
FavorávelEstudo em AnimaisInflamação Disfunção Cognitiva Doenças Neurodegenerativas Endocanabinoide (não especificado)Canabinoides Sintéticos O-x+1
2022
Pharmacological Aspects and Biological Effects of Cannabigerol and Its Synthetic Derivatives
FavorávelMetanáliseDor Câncer Inflamação Anandamida (AEA)Endocanabinoide (não especificado)+21
2022
Pharmacological effects of cannabidiol by transient receptor potential channels
FavorávelMetanáliseDor Câncer Inflamação+6
2022
Pharmacological management of cannabinoid hyperemesis syndrome: an update of the clinical literature
DesfavorávelMetanáliseEfeitos Adversos da Cannabis Náusea e Vômito Síndrome da Hiperêmese Canabinoide
2022
Pharmacological treatment of tremor in multiple sclerosis; a systematic review
InconclusivoMetanálise ClínicaDoenças Neurodegenerativas Esclerose Múltipla
2022
Phycocyanin Ameliorates Colitis-Associated Colorectal Cancer by Regulating the Gut Microbiota and the IL-17 Signaling Pathway
FavorávelEstudo em AnimaisCâncer DII — Doença Inflamatória Intestinal Câncer — Cólon Ficocianina
2022
Phycocyanin improved alcohol-induced hepatorenal toxicity and behavior impairment in Wistar rats
FavorávelEstudo em AnimaisInsuficiência Hepática Doença Hepática Alcoólica Ficocianina
2022
Phycocyanin stimulates ulcerative colitis healing via selective activation of cannabinoid receptor-2, intestinal mucosal healing, Treg accumulation, and p38MAPK/MK2 signaling inhibition
FavorávelEstudo em AnimaisInflamação DII — Doença Inflamatória Intestinal Desequilíbrio do Microbioma Microbioma Ficocianina
2022
Phytocannabinoid Compositions from Cannabis Act Synergistically with PARP1 Inhibitor against Ovarian Cancer Cells In Vitro and Affect the Wnt Signaling Pathway
FavorávelEstudo LaboratorialCâncer Câncer — Ovário Câncer — Colo do Útero Tetraidrocanabinol (THC)Canabigerol (CBG)+3
2022
Phytocannabinoids and Cannabis-Based Products as Alternative Pharmacotherapy in Neurodegenerative Diseases: From Hypothesis to Clinical Practice
InconclusivoMetanáliseInflamação Doenças Neurodegenerativas Esclerose Múltipla Anandamida (AEA)Tetraidrocanabinol (THC)+8
2022
Phytocannabinoids regulate inflammation in IL-1β-stimulated human gingival fibroblasts
FavorávelEstudo LaboratorialDor Inflamação Doença Periodontal Endocanabinoide (não especificado)Canabigerol (CBG)+2
2022
Phytol and Heptacosane Are Possible Tools to Overcome Multidrug Resistance in an In Vitro Model of Acute Myeloid Leukemia
FavorávelEstudo LaboratorialCâncer Câncer — Leucemia
2022
Phytol loaded PLGA nanoparticles ameliorate scopolamine-induced cognitive dysfunction by attenuating cholinesterase activity, oxidative stress and apoptosis in Wistar rat
FavorávelEstudo em AnimaisDisfunção Cognitiva Doença de Alzheimer
2022
Pilot clinical and pharmacokinetic study of Δ9-Tetrahydrocannabinol (THC)/Cannabidiol (CBD) nanoparticle oro-buccal spray in patients with advanced cancer experiencing uncontrolled pain
FavorávelEnsaio ClínicoDor Câncer Dor — Crônica Canabinol (CBN)Ácido Canabidiólico (CBD-a)+7
2022
Placebo Response and Media Attention in Randomized Clinical Trials Assessing Cannabis-Based Therapies for Pain: A Systematic Review and Meta-analysis
InconclusivoMetanálise ClínicaDor Esclerose Múltipla Dor — Neuropatia Periférica Tetraidrocanabinol (THC)THC Farmacêutico+1
2022
Plant-Derived Nanoscale-Encapsulated Antioxidants for Oral and Topical Uses: A Brief Review
FavorávelMetanáliseInflamação Estresse Oxidativo
2022
Plasma Pharmacokinetics of Cannabidiol Following Oral Administration of Cannabidiol Oil to Dairy Calves
FavorávelEstudo em AnimaisAplicações Veterinárias
2022
Pneumomediastinum and Pneumorrhachis Associated With Cannabinoid Hyperemesis Syndrome
DesfavorávelMetanáliseEfeitos Adversos da Cannabis Náusea e Vômito Dependência — Nicotina+1
2022
Pneumopericardium, Epidural Pneumatosis, and Muscular Emphysema: Rare Complications of Spontaneous Pneumomediastinum Due to Refractory Hyperemesis Gravidarum
DesfavorávelMetanáliseEfeitos Adversos da Cannabis Náusea e Vômito Gestação+2
2022
Popularity of Delta-8 THC on the Internet Across US States, 2021
FavorávelMetanáliseDelta-8-THC
2022
Post-Harvest Operations to Generate High-Quality Medicinal Cannabis Products: A Systemic Review
InconclusivoMetanáliseCanabigerol (CBG)Canabinol (CBN)+3
2022
Potency and Therapeutic THC and CBD Ratios: U.S. Cannabis Markets Overshoot
DesfavorávelMetanáliseDor Inflamação Efeitos Adversos da Cannabis Tetraidrocanabinol (THC)+5
2022
Potential anti-Parkinsonian's effect of S-(+)-linalool from Cinnamomum osmophloeum ct. linalool leaves are associated with mitochondrial regulation via gas-1, nuo-1, and mev-1 in Caenorhabditis elegans
FavorávelEstudo LaboratorialDoenças Neurodegenerativas Doença de Parkinson
2022
Potential effects of nicotine content in cigarettes on use of other substances
DesfavorávelEnsaio Clínico Duplo-CegoDependência Química Dependência — Cannabis Dependência — Álcool+4
2022
Potential Implications of Rimonabant on Age-Related Oxidative Stress and Inflammation
FavorávelEstudo em AnimaisInflamação Doenças Cardiovasculares (DCV)Estresse Oxidativo Canabinoide Sintético (não especificado)
2022
Potential protective effect of beta-caryophyllene against cadmium chloride-induced damage to the male reproductive system in mouse
FavorávelEstudo LaboratorialInflamação Estresse Oxidativo Infertilidade Masculina
2022
Potential use for chronic pain: Poly(Ethylene Glycol)-Poly(Lactic-Co-Glycolic Acid) nanoparticles enhance the effects of Cannabis-Based terpenes on calcium influx in TRPV1-Expressing cells
FavorávelEstudo LaboratorialDor Dor — Crônica
2022
Potential Utility of Cannabidiol in Stress-Related Disorders
FavorávelMetanáliseAnsiedade Transtornos de Comportamento TEPT Endocanabinoide (não especificado)
2022
Potentiation of the Activity of Antibiotics against ATCC and MDR Bacterial Strains with (+)-α-Pinene and (-)-Borneol
FavorávelEstudo LaboratorialInfecções Bacterianas
2022
Practical Considerations for the Use of Cannabis in Cancer Pain Management—What a Medical Oncologist Should Know
FavorávelMetanáliseDor Câncer Epilepsia Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+15
2022
Preclinical Assessment of the Abuse Potential of Purified Botanical Cannabidiol: Self-Administration, Drug Discrimination, and Physical Dependence
FavorávelMetanáliseDependência Química Efeitos Adversos da Cannabis Dependência — Cannabis CBD Farmacêutico+1
2022
Predictors of pain reduction among fibromyalgia patients using medical cannabis: a long-term prospective cohort study
FavorávelEnsaio ClínicoDor Ansiedade Dor — Crônica+3
2022
Prefrontal cortical distribution of muscarinic M2 and cannabinoid-1 (CB1) receptors in adult male mice with or without chronic adolescent exposure to Δ9-tetrahydrocannabinol
DesfavorávelEstudo em AnimaisEfeitos Adversos da Cannabis Disfunção Cognitiva Tetraidrocanabinol (THC)Endocanabinoide (não especificado)
2022
Pregnant People's Perspectives On Cannabis Use During Pregnancy: A Systematic Review and Integrative Mixed-Methods Research Synthesis
FavorávelMetanáliseDor Dependência Química Efeitos Adversos da Cannabis+8
2022
Premorbid characteristics of patients with DSM-IV psychotic disorders
DesfavorávelEnsaio ClínicoPsicose Esquizofrenia Transtorno Bipolar
2022
Prenatal cannabis exposure predicts attention problems, without changes on fMRI in adolescents
DesfavorávelEnsaio ClínicoDisfunção Cognitiva Gestação Transtornos de Comportamento+2
2022
Prenatal Nicotine or Cannabis Exposure and Offspring Neurobehavioral Outcomes
InconclusivoMetanáliseDependência Química Disfunção Cognitiva Síndrome Metabólica+4
2022
Prescription cannabidiol for seizure disorder management: Initial drug-drug interaction management by specialty pharmacists
FavorávelMetanáliseEfeitos Adversos da Cannabis Epilepsia Epilepsia — Lennox-Gastaut CBD Farmacêutico
2022
Prevalence and correlates of cannabis use disorder among Australians using cannabis products to treat a medical condition
DesfavorávelMetanáliseDor Dependência Química Câncer Tetraidrocanabinol (THC)+13
2022
Prevalence and self-reported reasons of cannabis use for medical purposes in USA and Canada
FavorávelMetanáliseDor Dor — Crônica Depressão+6