Dor — Neuropatia Periférica

termo de indexação original: Pain - Neuropathy - Peripheral

O acervo do Cannabis Indica reúne 174 estudos científicos que tocam a condição Dor — Neuropatia Periférica, publicados entre 1849 e 2024. Pela leitura automatizada, 139 (80%) foram classificados como favoráveis, 23 (13%) como inconclusivos e 12 (7%) como desfavoráveis — uma leitura de máquina, feita para navegar, não para concluir. O desenho mais frequente é metanálise (59 estudos), seguido de estudo em animais (36). Os compostos mais presentes são THC:CBD Farmacêutico, Tetraidrocanabinol (THC) e THC Farmacêutico. Aparece com frequência ao lado de Dor, Dor — Crônica e Inflamação.

Estudos indexados: 174
Período coberto: 1849–2024
Favoráveis: 139 · 80%
Inconclusivos: 23 · 13%
Desfavoráveis: 12 · 7%
Termo original: Pain - Neuropathy - Peripheral

O acervo em números

Tipo de estudo

Metanálise59

Estudo em Animais36

Metanálise Clínica29

Ensaio Clínico Duplo-Cego28

Ensaio Clínico17

Estudo Laboratorial5

Direção do resultado

Favorável139

Inconclusivo23

Desfavorável12

Por década

1840s1

1910s1

1990s1

2000s19

2010s73

2020s79

Aparece junto com

Dor172 Dor — Crônica90 Inflamação37 Dor — Polineuropatia Inflamatória36 Esclerose Múltipla29 Ansiedade25 Dor — Aguda25 Dor — Oncológica24

174 estudos

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2024
Design of Mixed Medicinal Plants, Rich in Polyphenols, Vitamins B, and Palmitoylethanolamide-Based Supplement to Help Reduce Nerve Pain: A Preclinical Study
FavorávelEstudo LaboratorialDor Inflamação Estresse Oxidativo Palmitoiletanolamida (PEA)+3
2024
Pharmacokinetics and pharmacodynamics of cannabis-based medicine in a patient population included in a randomized, placebo-controlled, clinical trial
InconclusivoEnsaio ClínicoDor Dor — Crônica Doenças Neurodegenerativas Tetraidrocanabinol (THC)Canabinoide Sintético (não especificado)+2
2024
The role of cannabinoids in chronic pain management: clinical insights and challenges
InconclusivoMetanáliseDor Inflamação Dor — Crônica+4
2024
Δ9-Tetrahydrocannabinol (THC): A Critical Overview of Recent Clinical Trials and Suggested Guidelines for Future Research
FavorávelMetanálise ClínicaDor Dependência Química Dependência — Cannabis Tetraidrocanabinol (THC)THC Farmacêutico+13
2023
Cannabidiol (CBD) Products for Pain: Ineffective, Expensive, and With Potential Harms
DesfavorávelMetanálise ClínicaDor — Crônica Dor — Aguda Dor — Oncológica+6
2023
Cannabidiol-Loaded Extracellular Vesicles from Human Umbilical Cord Mesenchymal Stem Cells Alleviate Paclitaxel-Induced Peripheral Neuropathy
FavorávelEstudo LaboratorialCâncer Inflamação Estresse Oxidativo THC Farmacêutico+12
2023
Cannabis-Based Medicine for Neuropathic Pain and Spasticity-A Multicenter, Randomized, Double-Blinded, Placebo-Controlled Trial
InconclusivoEnsaio Clínico Duplo-CegoDor Dor — Crônica Esclerose Múltipla Canabinoide Sintético (não especificado)+2
2023
Evidence-Based Treatment of Pain in Chemotherapy-Induced Peripheral Neuropathy
FavorávelMetanáliseDor Dor — Oncológica
2023
Palmitoylethanolamide in the Treatment of Chronic Pain: A Systematic Review and Meta-Analysis of Double-Blind Randomized Controlled Trials
FavorávelMetanálise ClínicaDor Inflamação Dor — Crônica Anandamida (AEA)Palmitoiletanolamida (PEA)+2
2023
Parosmia COVID-19 Related Treated by a Combination of Olfactory Training and Ultramicronized PEA-LUT: A Prospective Randomized Controlled Trial
FavorávelEnsaio ClínicoDor Inflamação COVID-19 Palmitoiletanolamida (PEA)
2023
The use of cannabidiol as a novel treatment for oral stereotypic behaviour (crib-biting) in a horse
FavorávelEstudo em AnimaisDor Inflamação Ansiedade Endocanabinoide (não especificado)+12
2022
A Coala-T-Cannabis Survey Study of breast cancer patients' use of cannabis before, during, and after treatment
FavorávelMetanáliseDor Câncer Ansiedade+5
2022
A randomized controlled trial assessing the safety and efficacy of palmitoylethanolamide for treating diabetic-related peripheral neuropathic pain
FavorávelEnsaio Clínico Duplo-CegoDor Inflamação Ansiedade Anandamida (AEA)Palmitoiletanolamida (PEA)+5
2022
An Updated Analysis of Clinical Outcome Measures Across Patients From the UK Medical Cannabis Registry
FavorávelEnsaio ClínicoDor Efeitos Adversos da Cannabis Ansiedade+3
2022
Anti-neuropathic pain mechanistic study of A. conyzoides essential oil, Precocene II, Caryophyllene, or Longifolene as single agent and in combination with pregabalin
FavorávelEstudo em AnimaisDor Dor — Crônica Dor — Aguda
2022
Cannabigerol (CBG) attenuates mechanical hypersensitivity elicited by chemotherapy-induced peripheral neuropathy
FavorávelEstudo em AnimaisDor Dor — Polineuropatia Induzida por Medicamentos Endocanabinoide (não especificado)Canabinoides Sintéticos AM-x+2
2022
Cannabinoids and Pain for the Plastic Surgeon: What Is the Evidence?
InconclusivoMetanáliseDor Inflamação Dependência — Opioides+1
2022
Cannabinoids for Symptom Management in Patients with Kidney Failure: A Narrative Review
DesfavorávelMetanáliseDor Inflamação Ansiedade+10
2022
Cannabinoids in the Orthopedic Setting: A Literature Review
DesfavorávelMetanáliseDor Dor — Crônica Dependência — Opioides+6
2022
Cannabis and orofacial pain: a systematic review
FavorávelMetanáliseDor Inflamação Dor — Crônica Canabinoide Sintético (não especificado)+1
2022
Cannabis-based medicines and medical cannabis for patients with neuropathic pain and other pain disorders: Nationwide register-based pharmacoepidemiologic comparison with propensity score matched controls
FavorávelMetanáliseDor Dor — Crônica Dor — Inflamatória
2022
Cannabis-Based Products for Chronic Pain : A Systematic Review
FavorávelMetanálise ClínicaDor Inflamação Dependência — Cannabis Tetraidrocanabinol (THC)THC Farmacêutico+7
2022
Changes in the expression of endocannabinoid system components in an experimental model of chemotherapy-induced peripheral neuropathic pain: Evaluation of sex-related differences
FavorávelEstudo em AnimaisDor Dor — Oncológica Náusea e Vômito por Quimioterapia Anandamida (AEA)Endocanabinoide (não especificado)+3
2022
Comparative Efficacy and Safety of 11 Drugs as Therapies for Adults With Neuropathic Pain After Spinal Cord Injury: A Bayesian Network Analysis Based on 20 Randomized Controlled Trials
InconclusivoMetanálise ClínicaDor Insônia e Distúrbios do Sono Dor — Polineuropatia Inflamatória+1
2022
Curcumin induces peripheral antinociception by opioidergic and cannabinoidergic mechanism: Pharmacological evidence
FavorávelEstudo em AnimaisDor Dor — Crônica Dor — Aguda Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+4
2022
Does Cannabidiol Have a Benefit as a Supportive Care Drug in Cancer?
FavorávelMetanáliseDor Câncer Efeitos Adversos da Cannabis Anandamida (AEA)Endocanabinoide (não especificado)+19
2022
Integrated Medical Cannabis Consultations in a Palliative Care Program: Policies, Procedures, and Progress after Six Years of Practice
FavorávelMetanáliseDor Câncer Dor — Crônica+1
2022
Intrathecal Actions of the Cannabis Constituents Δ(9)-Tetrahydrocannabinol and Cannabidiol in a Mouse Neuropathic Pain Model
FavorávelEstudo em AnimaisDor Dor — Crônica THC Farmacêutico Canabinoides Sintéticos AM-x+1
2022
Involvement of spinal G-protein inwardly rectifying potassium (GIRK) channels in the enhanced antinociceptive effects of the activation of both μ-opioid and cannabinoid CB1 receptors
FavorávelEstudo em AnimaisDor Dor — Nociceptiva Canabinoides Sintéticos WIN-x Canabinoides Sintéticos CP-x
2022
Long-term and serious harms of medical cannabis and cannabinoids for chronic pain: a systematic review of non-randomised studies
DesfavorávelMetanáliseDor Câncer Inflamação Anandamida (AEA)THC Farmacêutico+14
2022
Long-term observational studies with cannabis-based medicines for chronic non-cancer pain: A systematic review and meta-analysis of effectiveness and safety
FavorávelMetanáliseDor Ansiedade Dor — Crônica Hidrolase de Amidas de Ácidos Graxos (FAAH)THC Farmacêutico+5
2022
Oral capsules of tetra-hydro-cannabinol (THC), cannabidiol (CBD) and their combination in peripheral neuropathic pain treatment
DesfavorávelEnsaio Clínico Duplo-CegoDor Dor — Crônica Psicose+3
2022
Placebo Response and Media Attention in Randomized Clinical Trials Assessing Cannabis-Based Therapies for Pain: A Systematic Review and Meta-analysis
InconclusivoMetanálise ClínicaDor Esclerose Múltipla Tetraidrocanabinol (THC)THC Farmacêutico+1
2022
Practical Considerations for the Use of Cannabis in Cancer Pain Management—What a Medical Oncologist Should Know
FavorávelMetanáliseDor Câncer Epilepsia Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+14
2022
Spinal cannabinoid CB1 or CB2 receptors activation attenuates mechanical allodynia in streptozotocin-induced diabetic rats
FavorávelEstudo em AnimaisDor Dor — Crônica Diabetes Endocanabinoide (não especificado)Canabinoides Sintéticos AM-x+3
2022
Systematic reviews of randomized controlled trials of cannabinoid products in chronic pain conditions and for symptoms associated with multiple sclerosis: what do they tell us?
InconclusivoMetanálise ClínicaDor Dor — Crônica Esclerose Múltipla+1
2022
The effect of medical cannabis on cognitive functions: a systematic review
DesfavorávelMetanálise ClínicaDor Câncer Efeitos Adversos da Cannabis THC:CBD Farmacêutico CBD Farmacêutico+11
2022
The intersection between integrative medicine and neuropathic pain: A case report
FavorávelMetanáliseDor Ansiedade Dor — Crônica Medicina Mente-Corpo Acupuntura (MTC)+2
2022
Therapeutic effect of palmitoylethanolamide in cognitive decline: A systematic review and preliminary meta-analysis of preclinical and clinical evidence
FavorávelMetanálise ClínicaDor Inflamação Disfunção Cognitiva Palmitoiletanolamida (PEA)+8
2022
TRPV1: A Common Denominator Mediating Antinociceptive and Antiemetic Effects of Cannabinoids
FavorávelMetanáliseDor Inflamação Efeitos Adversos da Cannabis Anandamida (AEA)Endocanabinoide (não especificado)+18
2021
A systematic review and meta-analysis of cannabis-based medicines, cannabinoids and endocannabinoid system modulators tested for antinociceptive effects in animal models of injury-related or pathological persistent pain
FavorávelMetanáliseDor Dor — Crônica Dor — Nociceptiva Outros Compostos Relacionados+1
2021
An overview of ongoing clinical trials assessing pharmacological therapeutic strategies to manage chemotherapy-induced peripheral neuropathy, based on preclinical studies in rodent models
InconclusivoMetanáliseDor Câncer Estresse Oxidativo Endocanabinoide (não especificado)+2
2021
Cannabidiol effectively reverses mechanical and thermal allodynia, hyperalgesia, and anxious behaviors in a neuropathic pain model: Possible role of CB1 and TRPV1 receptors
FavorávelEstudo em AnimaisDor Ansiedade Dor — Crônica+1
2021
Cannabinoids, cannabis, and cannabis-based medicine for pain management: a systematic review of randomised controlled trials
InconclusivoMetanálise ClínicaDor Dor — Crônica Dor — Aguda THC Farmacêutico THC:CBD Farmacêutico+5
2021
Cannabinoids, cannabis, and cannabis-based medicines for pain management: an overview of systematic reviews
InconclusivoMetanálise ClínicaDor Dor — Crônica Dor — Aguda+4
2021
Cannabinoids, the endocannabinoid system, and pain: a review of preclinical studies
FavorávelMetanáliseDor Dor — Crônica Dor — Nociceptiva+1
2021
Cost-Effectiveness of Medicinal Cannabis for Management of Refractory Symptoms Associated With Chronic Conditions: A Systematic Review of Economic Evaluations
FavorávelMetanáliseDor Dor — Crônica Epilepsia THC Farmacêutico THC:CBD Farmacêutico+7
2021
Effect of cannabis on oxaliplatin-induced peripheral neuropathy among oncology patients: a retrospective analysis
FavorávelEnsaio ClínicoDor Câncer Dor — Oncológica
2021
Effect of Ultra-Micronized-Palmitoylethanolamide and Acetyl-l-Carnitine on Experimental Model of Inflammatory Pain
FavorávelEstudo em AnimaisDor Inflamação Dor — Crônica Endocanabinoide (não especificado)Palmitoiletanolamida (PEA)+2
2021
Effectiveness, safety and tolerability of nabiximols oromucosal spray versus typical oral long-acting opioid analgesics in patients with severe neuropathic back pain: analysis of 6-month real-world data from the German Pain e-Registry
FavorávelMetanáliseDor Dor — Crônica THC:CBD Farmacêutico
2021
Efficacy of a fixed combination of palmitoylethanolamide and acetyl-l-carnitine (PEA+ALC FC) in the treatment of neuropathies secondary to rheumatic diseases
FavorávelEnsaio ClínicoDor Inflamação Dor — Crônica Palmitoiletanolamida (PEA)+3
2021
International Association for the Study of Pain Presidential Task Force on Cannabis and Cannabinoid Analgesia: research agenda on the use of cannabinoids, cannabis, and cannabis-based medicines for pain management
FavorávelMetanáliseDor Dor — Crônica Dor — Aguda+5
2021
Oral efficacy of Δ(9)-tetrahydrocannabinol and cannabidiol in a mouse neuropathic pain model
FavorávelEstudo em AnimaisDor Dor — Crônica
2021
Palmitoylethanolamide (PEA) in the treatment of neuropathic pain: a case study
FavorávelMetanáliseDor Herpes Herpes-Zóster Palmitoiletanolamida (PEA)
2021
Protective effects of anandamide against cisplatin-induced peripheral neuropathy in rats
FavorávelEstudo em AnimaisDor Dor — Polineuropatia Induzida por Medicamentos Anandamida (AEA)
2021
Safety and tolerability of nabiximols oromucosal spray: a review of more than 15 years" accumulated evidence from clinical trials
FavorávelMetanálise ClínicaDor Dor — Crônica Doenças Neurodegenerativas THC:CBD Farmacêutico+5
2021
Targeting the endocannabinoid system for management of HIV-associated neuropathic pain: A systematic review
FavorávelMetanáliseDor HIV/AIDS Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+5
2021
The dose-dependent analgesic effects, abuse liability, safety and tolerability of oral cannabidiol in healthy humans
InconclusivoEnsaio Clínico Duplo-CegoDor Dor — Aguda Dor — Nociceptiva
2021
The Effect of Medical Cannabis on Pain Level and Quality of Sleep among Rheumatology Clinic Outpatients
FavorávelMetanáliseDor Inflamação Efeitos Adversos da Cannabis+8
2021
The Effects of Cannabinoids on Pro- and Anti-Inflammatory Cytokines: A Systematic Review of In Vivo Studies
FavorávelMetanáliseDor Inflamação Canabigerol (CBG)
2021
The Efficacy, Adverse Events, and Withdrawal Rates of the Pharmacological Management of Chronic Spinal Cord Injury Pain: A Systematic Review and Meta-Analysis
DesfavorávelMetanáliseDor Dor — Crônica Lesões da Medula Espinhal
2021
The Safety of Medications used to Treat Peripheral Neuropathic Pain, Part 2 (Opioids, Cannabinoids and Other Drugs): review of Double-Blind, Placebo-Controlled, Randomized Clinical Trials
DesfavorávelMetanálise ClínicaDor
2021
The terpenes camphene and alpha-bisabolol inhibit inflammatory and neuropathic pain via Cav3.2 T-type calcium channels
FavorávelEstudo em AnimaisDor Inflamação Dor — Crônica+1
2021
Topical Cannabinoids for Treating Chemotherapy-Induced Neuropathy: A Case Series
FavorávelMetanáliseDor Câncer Inflamação
2021
Transcriptomic Profiling in Mice With CB1 receptor Deletion in Primary Sensory Neurons Suggests New Analgesic Targets for Neuropathic Pain
FavorávelEstudo em AnimaisDor Inflamação Dor — Crônica Endocanabinoide (não especificado)Canabinoides Sintéticos AM-x+1
2020
A Large-Scale Naturalistic Examination of the Acute Effects of Cannabis on Pain
FavorávelMetanáliseDor Dor — Crônica Dor — Aguda+1
2020
ALIAmides Update: Palmitoylethanolamide and Its Formulations on Management of Peripheral Neuropathic Pain
FavorávelMetanáliseDor Palmitoiletanolamida (PEA)
2020
An evaluation of the anti-hyperalgesic effects of cannabidiolic acid-methyl ester in a preclinical model of peripheral neuropathic pain
FavorávelEstudo em AnimaisDor Dor — Crônica Ácido Canabidiólico (CBD-a)
2020
Associating Emergency Medical Services personnel's workload, trauma exposure, and health with the cortisol, endocannabinoid, and N-acylethanolamine concentrations in their hair
DesfavorávelEnsaio ClínicoDor Ansiedade Depressão Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+4
2020
Evaluation of the preclinical analgesic efficacy of naturally derived, orally administered oil forms of Δ9-tetrahydrocannabinol (THC), cannabidiol (CBD), and their 1:1 combination
FavorávelEstudo em AnimaisDor Inflamação Dor — Crônica Tetraidrocanabinol (THC)Ácido Canabidiólico (CBD-a)+1
2020
Mapping cannabis potency in medical and recreational programs in the United States
DesfavorávelMetanáliseDor Ansiedade Dor — Crônica Tetraidrocanabinol (THC)+4
2020
Measuring the placebo effect in carpal tunnel syndrome
FavorávelEnsaio Clínico Duplo-CegoDor Dor — Crônica Artrite Palmitoiletanolamida (PEA)+1
2020
Pharmacological treatment of central neuropathic pain: consensus of the Brazilian Academy of Neurology
FavorávelMetanáliseDor Depressão Esclerose Múltipla Tetraidrocanabinol (THC)THC Farmacêutico+6
2020
Terpenes/Terpenoids in Cannabis: Are They Important?
FavorávelMetanáliseDor Câncer Inflamação+10
2020
The anti-inflammatory and analgesic effects of formulated full-spectrum cannabis extract in the treatment of neuropathic pain associated with multiple sclerosis
FavorávelMetanálise ClínicaDor Esclerose Múltipla Dor — Polineuropatia Inflamatória
2020
The Cannabis Terpenes
FavorávelMetanáliseDor Câncer Inflamação+10
2020
The pharmacological effects of inhaled cannabis on pain in patients with multiple sclerosis: risks versus rewards
FavorávelMetanáliseDor Esclerose Múltipla
2020
Ultramicronized Palmitoylethanolamide and Paracetamol, a New Association to Relieve Hyperalgesia and Pain in a Sciatic Nerve Injury Model in Rat
FavorávelEstudo em AnimaisDor Inflamação Estresse Oxidativo Palmitoiletanolamida (PEA)+2
2020
Understanding Cannabis-Based Therapeutics in Sports Medicine
FavorávelMetanáliseDor Dor — Crônica Estresse Oxidativo+4
2019
Analgesic Effect of α-Terpineol on Neuropathic Pain Induced by Chronic Constriction Injury in Rat Sciatic Nerve: Involvement of Spinal Microglial Cells and Inflammatory Cytokines
FavorávelEstudo em AnimaisDor Dor — Neuropatia Diabética
2019
Antiallodynic Effects of Cannabinoid Receptor 2 (CB2R) Agonists on Retrovirus Infection-Induced Neuropathic Pain
FavorávelEstudo em AnimaisDor Inflamação Doenças Priônicas Canabinoides Sintéticos JWH-x Canabinoides Sintéticos HU-x
2019
Benefit of Tetrahydrocannabinol versus Cannabidiol for Common Palliative Care Symptoms
FavorávelMetanáliseDor Ansiedade Depressão+4
2019
Diverse TRPV1 responses to cannabinoids
InconclusivoEstudo LaboratorialDor Dor — Crônica Canabigerol (CBG)Canabinol (CBN)
2019
Evidence for the involvement of opioid and cannabinoid systems in the peripheral antinociception mediated by resveratrol
FavorávelEstudo em AnimaisDor Endocanabinoide (não especificado)Resveratrol
2019
Micronized Palmitoylethanolamide: A Post Hoc Analysis of a Controlled Study in Patients with Low Back Pain – Sciatica
FavorávelMetanáliseDor Inflamação Dor — Crônica Palmitoiletanolamida (PEA)
2019
Plant-derived medicines for neuropathies: a comprehensive review of clinical evidence
FavorávelMetanálise ClínicaDor
2019
THC and gabapentin interactions in a mouse neuropathic pain model
FavorávelEstudo em AnimaisDor
2019
The Effectiveness of Topical Cannabidiol Oil in Symptomatic Relief of Peripheral Neuropathy of the Lower Extremities
FavorávelEnsaio Clínico Duplo-CegoDor
2018
Cannabis for chronic pain: Not a simple solution
InconclusivoMetanáliseDor Dor — Crônica
2018
Cannabis for peripheral neuropathy: The good, the bad, and the unknown
FavorávelMetanáliseDor
2018
Medical Cannabis for Neuropathic Pain.
FavorávelMetanáliseDor Endocanabinoide (não especificado)Canabinoide Sintético (não especificado)
2018
Medical use of cannabis: Italian and European legislation.
FavorávelMetanáliseDor Ansiedade Esclerose Múltipla THC Farmacêutico THC:CBD Farmacêutico+9
2018
Pharmacotherapeutic considerations for use of cannabinoids to relieve pain in patients with malignant diseases
FavorávelMetanáliseDor Dor — Crônica Artrite Tetraidrocanabinol (THC)THC Farmacêutico+3
2018
Preliminary evaluation of the efficacy, safety, and costs associated with the treatment of chronic pain with medical cannabis
FavorávelEnsaio ClínicoDor Câncer Dor — Crônica+6
2018
Role of palmitoylethanolamide (PEA) in depression: Translational evidence: Special Section on "Translational and Neuroscience Studies in Affective Disorders".
FavorávelMetanáliseDor Ansiedade Depressão Endocanabinoide (não especificado)Palmitoiletanolamida (PEA)+1
2018
Systematic review of systematic reviews for medical cannabinoids: Pain, nausea and vomiting, spasticity, and harms.
FavorávelMetanáliseDor Dor — Crônica Esclerose Múltipla+2
2018
The Involvement of the Endocannabinoid System in the Peripheral Antinociceptive Action of Ketamine
FavorávelEstudo em AnimaisDor Dor — Polineuropatia Inflamatória
2018
Therapeutic Benefit of Smoked Cannabis in Randomized Placebo-Controlled Studies
InconclusivoMetanálise ClínicaDor Efeitos Adversos da Cannabis Doenças Cardiovasculares (DCV)Tetraidrocanabinol (THC)THC Farmacêutico+8
2017
Allodynia Lowering Induced by Cannabinoids and Endocannabinoids (ALICE).
FavorávelMetanáliseDor Dor — Crônica Endocanabinoide (não especificado)
2017
Cannabinoids and Pain: Sites and Mechanisms of Action.
FavorávelMetanáliseDor Dor — Aguda Dor — Polineuropatia Inflamatória Endocanabinoide (não especificado)Canabinoide Sintético (não especificado)
2017
Cannabis constituent synergy in a mouse neuropathic pain model
FavorávelEstudo em AnimaisDor Dor — Crônica Tetraidrocanabinol (THC)
2017
Dronabinol Is a Safe Long-Term Treatment Option for Neuropathic Pain Patients
FavorávelEnsaio Clínico Duplo-CegoDor Inflamação Ansiedade THC Farmacêutico+4
2017
Effect of Treatment With Geraniol on Ovalbumin-Induced Allergic Asthma in Mice
FavorávelEstudo em AnimaisDor Lesões da Medula Espinhal
2017
Effects on Spasticity and Neuropathic Pain of an Oral Formulation of Δ9-tetrahydrocannabinol in Patients WithProgressive Multiple Sclerosis
FavorávelEnsaio Clínico Duplo-CegoDor Inflamação Esclerose Múltipla Tetraidrocanabinol (THC)Canabinoide Sintético (não especificado)
2017
Efficacy of Cannabis-Based Medicines for Pain Management: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
FavorávelMetanálise ClínicaDor Dor — Crônica Dor — Polineuropatia Inflamatória+2
2017
Efficacy of Palmitoylethanolamide for Pain: A Meta-Analysis
FavorávelMetanálise ClínicaDor Dor — Crônica Dor — Aguda Palmitoiletanolamida (PEA)
2017
Medical Cannabinoids in Children and Adolescents: A Systematic Review.
FavorávelMetanáliseDor Epilepsia Náusea e Vômito+2
2017
Opioid-Sparing Effect of Cannabinoids: A Systematic Review and Meta-Analysis.
FavorávelMetanáliseDor Dependência Química Dependência — Opioides Tetraidrocanabinol (THC)THC Farmacêutico+8
2017
Selective Cannabinoids for Chronic Neuropathic Pain: A Systematic Review and Meta-analysis
FavorávelMetanálise ClínicaDor Dor — Crônica Dor — Polineuropatia Inflamatória THC Farmacêutico THC:CBD Farmacêutico+3
2017
Use of palmitoylethanolamide in carpal tunnel syndrome: a prospective randomized study
InconclusivoEnsaio Clínico Duplo-CegoDor Inflamação Dor — Crônica Palmitoiletanolamida (PEA)+5
2016
(+)-Borneol Attenuates Oxaliplatin-Induced Neuropathic Hyperalgesia in Mice
FavorávelEstudo em AnimaisDor
2016
An Exploratory Human Laboratory Experiment Evaluating Vaporized Cannabis in the Treatment of Neuropathic Pain From Spinal Cord Injury and Disease.
FavorávelEnsaio Clínico Duplo-CegoDor Lesões da Medula Espinhal Dor — Síndrome da Dor Central
2016
Antioxidant Activity of Linalool in Patients With Carpal Tunnel Syndrome
FavorávelEnsaio Clínico Duplo-CegoDor Doenças Cardiovasculares (DCV)Estresse Oxidativo+1
2016
Cannabidivarin for HIV-Associated Neuropathic Pain: A Randomized, Blinded, Controlled Clinical Trial
InconclusivoEnsaio Clínico Duplo-CegoDor HIV/AIDS Canabidivarina (CBDV)
2016
Efficacy, tolerability and safety of cannabinoids for chronic neuropathic pain: A systematic review of randomized controlled studies.
FavorávelMetanálise ClínicaDor Dor — Crônica Canabinoide Sintético (não especificado)THC Farmacêutico+1
2016
Evaluating Sativex® in Neuropathic Pain Management: A Clinical and Neurophysiological Assessment in Multiple Sclerosis
FavorávelEnsaio ClínicoDor Inflamação Dor — Crônica THC:CBD Farmacêutico+4
2016
Inhaled cannabis for chronic neuropathic pain: an individual patient data meta-analysis
FavorávelMetanálise ClínicaDor Dor — Crônica
2016
Ocimum Gratissimum Essential Oil and Its Isolated Compounds (Eugenol and Myrcene) Reduce Neuropathic Pain in Mice
FavorávelEstudo em AnimaisDor
2016
Palmitoylethanolamide Reverses Paclitaxel-Induced Allodynia in Mice
FavorávelEstudo em AnimaisDor Câncer Dor — Aguda Canabinoides Sintéticos SR-x Palmitoiletanolamida (PEA)
2015
(+)-Borneol alleviates mechanical hyperalgesia in models of chronic inflammatory and neuropathic pain in mice
FavorávelEstudo em AnimaisDor Inflamação Dor — Crônica+1
2015
[Assessment of the effectiveness and safety of Sativex® in compassionate use]
FavorávelEnsaio ClínicoDor Dor — Crônica THC:CBD Farmacêutico
2015
Chronic cannabinoid receptor 2 activation reverses paclitaxel neuropathy without tolerance or cannabinoid receptor 1-dependent withdrawal
FavorávelEstudo em AnimaisDor Câncer Efeitos Adversos da Cannabis Tetraidrocanabinol (THC)Canabinoides Sintéticos AM-x+3
2015
Efficacy and adverse effects of medical marijuana for chronic noncancer pain: Systematic review of randomized controlled trials
FavorávelMetanálise ClínicaDor Dor — Crônica Esclerose Múltipla Tetraidrocanabinol (THC)+5
2015
Medical Marijuana for Treatment of Chronic Pain and Other Medical and Psychiatric Problems: A Clinical Review
FavorávelMetanálise ClínicaDor Dor — Crônica Esclerose Múltipla
2015
Physicochemical characterization and analgesic effect of inclusion complexes of essential oil from Hyptis pectinata L. Poit leaves with β-cyclodextrin.
FavorávelEstudo em AnimaisDor Dor — Polineuropatia Inflamatória
2015
Single dose delta-9-tetrahydrocannabinol in chronic pancreatitis patients: analgesic efficacy, pharmacokinetics and tolerability
InconclusivoEnsaio Clínico Duplo-CegoDor Dor — Crônica Dependência — Opioides Canabinoide Sintético (não especificado)THC Farmacêutico+3
2015
The effectiveness of cannabinoids in the management of chronic nonmalignant neuropathic pain: a systematic review
InconclusivoMetanálise ClínicaDor Dor — Crônica
2014
A double-blind, randomized, placebo-controlled, parallel group study of THC/CBD spray in peripheral neuropathic pain treatment
FavorávelEnsaio Clínico Duplo-CegoDor Insônia e Distúrbios do Sono Tetraidrocanabinol (THC)THC:CBD Farmacêutico
2014
A multicentre, open-label, follow-on study to assess the long-term maintenance of effect, tolerance and safety of THC/CBD oromucosal spray in the management of neuropathic pain
FavorávelEnsaio ClínicoDor Dor — Neuropatia Diabética Tetraidrocanabinol (THC)THC:CBD Farmacêutico
2014
In vivo characterization of the highly selective monoacylglycerol lipase inhibitor KML29: antinociceptive activity without cannabimimetic side effects
FavorávelEstudo em AnimaisDor Inflamação DII — Doença Inflamatória Intestinal Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+10
2014
Nabilone as an Adjunctive to Gabapentin for Multiple Sclerosis-Induced Neuropathic Pain: A Randomized Controlled Trial
FavorávelEnsaio Clínico Duplo-CegoDor Dor — Crônica Esclerose Múltipla Tetraidrocanabinol (THC)THC Farmacêutico
2014
Prescribing smoked cannabis for chronic noncancer pain: preliminary recommendations
FavorávelMetanálise ClínicaDor Dor — Crônica
2014
The pharmacokinetics, efficacy, safety, and ease of use of a novel portable metered-dose cannabis inhaler in patients with chronic neuropathic pain: a phase 1a study
FavorávelEnsaio ClínicoDor Dor — Crônica Canabinol (CBN)
2013
A double-blind, placebo-controlled, crossover pilot trial with extension using an oral mucosal cannabinoid extract for treatment of chemotherapy-induced neuropathic pain
FavorávelEnsaio ClínicoDor Câncer Ansiedade THC:CBD Farmacêutico+5
2013
Alterations in endocannabinoid tone following chemotherapy-induced peripheral neuropathy: effects of endocannabinoid deactivation inhibitors targeting fatty-acid amide hydrolase and monoacylglycerol lipase in comparison to reference analgesics following cisplatin treatment
FavorávelEstudo em AnimaisDor Dor — Polineuropatia Induzida por Medicamentos Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+2
2013
Anandamide deficiency and heightened neuropathic pain in aged mice
FavorávelEstudo em AnimaisDor Anandamida (AEA)
2013
Low Dose Vaporized Cannabis Significantly Improves Neuropathic Pain.
FavorávelEnsaio Clínico Duplo-CegoDor Dor — Síndrome da Dor Central Tetraidrocanabinol (THC)
2012
A double-blind, randomized, placebo-controlled, parallel-group study of THC/CBD oromucosal spray in combination with the existing treatment regimen, in the relief of central neuropathic pain in patients with multiple sclerosis
InconclusivoEnsaio Clínico Duplo-CegoDor Dor — Crônica Esclerose Múltipla THC:CBD Farmacêutico+1
2012
An enriched-enrolment, randomized withdrawal, flexible-dose, double-blind, placebo-controlled, parallel assignment efficacy study of nabilone as adjuvant in the treatment of diabetic peripheral neuropathic pain
FavorávelEnsaio Clínico Duplo-CegoDor Ansiedade Dor — Crônica THC Farmacêutico+3
2012
An open-label extension study to investigate the long-term safety and tolerability of THC/CBD oromucosal spray and oromucosal THC spray in patients with terminal cancer-related pain refractory to strong opioid analgesics
FavorávelEnsaio ClínicoDor Câncer Ansiedade Endocanabinoide (não especificado)THC Farmacêutico+10
2012
Palmitoylethanolamide in the treatment of chronic pain caused by different etiopathogenesis
FavorávelEnsaio ClínicoDor Dor — Crônica Diabetes Palmitoiletanolamida (PEA)+4
2012
Prescribing Cannabis For Harm Reduction
FavorávelMetanáliseDor Dependência — Opioides
2012
Targeting the endocannabinoid system with cannabinoid receptor agonists: pharmacological strategies and therapeutic possibilities.
FavorávelMetanáliseDor Esclerose Múltipla Náusea e Vômito Tetraidrocanabinol (THC)THC Farmacêutico+4
2012
The CB2 cannabinoid receptor-selective agonist O-3223 reduces pain and inflammation without apparent cannabinoid behavioral effects
FavorávelEstudo em AnimaisDor Inflamação Dor — Crônica Canabinoides Sintéticos O-x+1
2011
Cannabidiol as an Emergent Therapeutic Strategy for Lessening the Impact of Inflammation on Oxidative Stress.
FavorávelMetanáliseDor Doenças Cardiovasculares (DCV)Depressão Hidrolase de Amidas de Ácidos Graxos (FAAH)+10
2011
Cannabinoids for treatment of chronic non-cancer pain; a systematic review of randomized trials.
FavorávelMetanálise ClínicaDor Dor — Crônica Artrite THC Farmacêutico THC:CBD Farmacêutico+2
2011
Palmitoylethanolamide restores myelinated-fibre function in patients with chemotherapy-induced painful neuropathy
FavorávelEnsaio Clínico Duplo-CegoDor Dor — Oncológica Câncer — Mieloma Palmitoiletanolamida (PEA)
2010
Adjuvant topical therapy with a cannabinoid receptor agonist in facial postherpetic neuralgia.
FavorávelEnsaio ClínicoDor Herpes Herpes-Zóster Endocanabinoide (não especificado)Outros Compostos Relacionados
2010
An open-label comparison of nabilone and gabapentin as adjuvant therapy or monotherapy in the management of neuropathic pain in patients with peripheral neuropathy
FavorávelEnsaio ClínicoDor THC Farmacêutico
2010
Mutations in ABHD12 Cause the Neurodegenerative Disease PHARC: An Inborn Error of Endocannabinoid Metabolism
InconclusivoEstudo LaboratorialDor Doenças Neurodegenerativas Doenças da Retina 2-Araquidonoilglicerol (2-AG)+2
2010
Pharmacological treatment of painful HIV-associated sensory neuropathy: a systematic review and meta-analysis of randomised controlled trials
FavorávelMetanálise ClínicaDor HIV/AIDS Dor — Polineuropatia Inflamatória
2010
Smoked cannabis for chronic neuropathic pain: a randomized controlled trial
FavorávelEnsaio Clínico Duplo-CegoDor Dor — Crônica Tetraidrocanabinol (THC)
2009
Cannabinoids, Endocannabinoids, and Related Analogs in Inflammation
FavorávelMetanáliseDor Dor — Crônica Dor — Aguda Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+12
2009
Chronic neuropathic pain management in spinal cord injury patients. What is the efficacy of pharmacological treatments with a general mode of administration? (oral, transdermal, intravenous)
DesfavorávelMetanálise ClínicaDor Dor — Polineuropatia Inflamatória
2009
Smoked Medicinal Cannabis for Neuropathic Pain in HIV: A Randomized, Crossover Clinical Trial
FavorávelEnsaio Clínico Duplo-CegoDor HIV/AIDS Tetraidrocanabinol (THC)
2008
A Randomized, Placebo-Controlled, Crossover Trial of Cannabis Cigarettes in Neuropathic Pain.
FavorávelEnsaio Clínico Duplo-CegoDor Dor — Síndrome da Dor Central Tetraidrocanabinol (THC)
2008
Comparison of analgesic effects and patient tolerability of nabilone and dihydrocodeine for chronic neuropathic pain: randomised, crossover, double blind study
InconclusivoEnsaio Clínico Duplo-CegoDor THC Farmacêutico
2008
Complementary therapies for neuropathic and neuralgic pain: systematic review
DesfavorávelMetanálise ClínicaDor Dor — Polineuropatia Inflamatória Dor — Neuropatia Diabética+1
2008
Further characterisation of a rat model of varicella zoster virus (VZV)-associated pain
FavorávelEstudo em AnimaisDor Herpes Herpes-Zóster Canabinoides Sintéticos WIN-x
2007
Cannabis In Painful HIV-associated Sensory Neuropathy: A Randomized Placebo-controlled Trial
FavorávelEnsaio Clínico Duplo-CegoDor HIV/AIDS Tetraidrocanabinol (THC)
2007
Cannabis, pain, and sleep: lessons from therapeutic clinical trials of Sativex, a cannabis-based medicine
FavorávelEnsaio ClínicoDor Insônia e Distúrbios do Sono Esclerose Múltipla THC:CBD Farmacêutico+3
2007
Sativex successfully treats neuropathic pain characterised by allodynia: a randomised, double-blind, placebo-controlled clinical trial
FavorávelEnsaio Clínico Duplo-CegoDor THC:CBD Farmacêutico
2006
Sativex®: clinical efficacy and tolerability in the treatment of symptoms of multiple sclerosis and neuropathic pain.
FavorávelMetanáliseDor Esclerose Múltipla Tetraidrocanabinol (THC)THC:CBD Farmacêutico
2005
Antihyperalgesic properties of the cannabinoid CT-3 in chronic neuropathic and inflammatory pain states in the rat
FavorávelEstudo LaboratorialDor Inflamação Dor — Crônica Tetraidrocanabinol (THC)Canabinoides Sintéticos WIN-x+3
2005
Cannabis use in HIV for pain and other medical symptoms
FavorávelMetanáliseDor HIV/AIDS
2005
Involvement of the cannabimimetic compound, N-palmitoyl-ethanolamine, in inflammatory and neuropathic conditions: review of the available pre-clinical data, and first human studies.
FavorávelMetanáliseDor Dor — Polineuropatia Inflamatória Outros Compostos Relacionados
2005
Pain measurements and side effect profile of the novel cannabinoid ajulemic acid
FavorávelEnsaio Clínico Duplo-CegoDor Dor — Crônica Canabinoide Sintético (não especificado)
2005
Therapeutic opportunities through modulation of the endocannabinoid system
InconclusivoMetanáliseDor Inflamação Dor — Polineuropatia Inflamatória Anandamida (AEA)Tetraidrocanabinol (THC)+9
2004
Are oral cannabinoids safe and effective in refractory neuropathic pain?
InconclusivoEnsaio Clínico Duplo-CegoDor Ansiedade Dor — Crônica+1
2003
Analgesic Effect of the Synthetic Cannabinoid CT-3 on Chronic Neuropathic Pain: A Randomized Controlled Trial
FavorávelEnsaio Clínico Duplo-CegoDor Dor — Crônica Delta-8-THC
2003
CB2 cannabinoid receptor agonists: pain relief without psychoactive effects?
FavorávelMetanáliseDor Inflamação Dor — Crônica Tetraidrocanabinol (THC)Endocanabinoide (não especificado)+5
1991
Myrcene mimics the peripheral analgesic activity of lemongrass tea.
FavorávelEstudo em AnimaisDor
1918
Dispensatory of the United States, 20th ed. (1918)
FavorávelMetanáliseDor Ansiedade Dor — Crônica+4
1849
Indian Hemp in Facial Neuralgia
FavorávelMetanáliseDor Dor — Crônica Dor — Aguda

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Canabinoides e compostos

THC:CBD Farmacêutico 29 Tetraidrocanabinol (THC) 27 THC Farmacêutico 26 Palmitoiletanolamida (PEA) 22 Endocanabinoide (não especificado) 17 Anandamida (AEA) 16 2-Araquidonoilglicerol (2-AG) 11 Canabinoides Sintéticos AM-x 11

Sistemas do corpo

Sistema Nervoso 106 Saúde Mental e Emocional 8 Sistema Esquelético 7 Sistema Imunológico 6 Sistema Digestório 3 Sistema Endócrino 3

Perguntas frequentes

Quantos estudos sobre dor — neuropatia periférica estão indexados no acervo?

São 174 estudos, publicados entre 1849 e 2024. O acervo inteiro tem 7.640 registros.

Que tipos de estudo predominam?

Metanálise: 59 · Estudo em Animais: 36 · Metanálise Clínica: 29 · Ensaio Clínico Duplo-Cego: 28 · Ensaio Clínico: 17 · Estudo Laboratorial: 5. A classificação segue o desenho declarado na fonte.

O que significa a classificação de resultado?

É uma leitura automatizada da conclusão de cada estudo, em três direções — favorável, inconclusivo e desfavorável. Aqui são 139 favoráveis, 23 inconclusivos e 12 desfavoráveis. Serve para navegar o acervo, não para concluir nada clinicamente: a conclusão válida é a do artigo original.

Como citar esta página

ABNT

CANNABIS INDICA. Dor — Neuropatia Periférica — estudos científicos sobre cannabis. 2026. Disponível em: https://cannabisindica.com.br/condicao/dor-neuropatia-periferica/. Acesso em: 13 set. 2026.

APA

Cannabis Indica. (2026). Dor — Neuropatia Periférica — estudos científicos sobre cannabis. https://cannabisindica.com.br/condicao/dor-neuropatia-periferica/

Esta página é um índice de acesso. Ao usar um estudo como evidência, cite o artigo original — o link de cada registro leva à fonte.