cannabis indica

Endocanabinoide (não especificado)

termo de indexação original: Endocannabinoid (unspecified)

Como esta categoria funciona

Esta não é uma molécula, e sim uma categoria do acervo. Agrupa os estudos que tratam do sistema endocanabinoide de forma geral — falando em "tônus endocanabinoide", "sinalização endocanabinoide" ou "níveis de endocanabinoides" — sem que a classificação tenha identificado qual composto está em jogo.

É o caso de boa parte das revisões e dos artigos conceituais, que discutem o sistema como conjunto: receptores CB1 e CB2, os ligantes endógenos e as enzimas que os produzem e degradam.

Se você procura um endocanabinoide específico, os principais têm página própria: anandamida, 2-AG, virodamina e NADA.

No acervo

O acervo do Cannabis Indica reúne 570 estudos científicos que tocam o composto Endocanabinoide (não especificado), publicados entre 1996 e 2024. Pela leitura automatizada, 453 (79%) foram classificados como favoráveis, 82 (14%) como inconclusivos e 35 (6%) como desfavoráveis — uma leitura de máquina, feita para navegar, não para concluir. O desenho mais frequente é metanálise (317 estudos), seguido de estudo em animais (116). As condições mais associadas são Inflamação, Dor e Ansiedade.

Estudos indexados
570
Período coberto
1996–2024
Favoráveis
453 · 79%
Inconclusivos
82 · 14%
Desfavoráveis
35 · 6%
Termo original
Endocannabinoid (unspecified)

O acervo em números

Tipo de estudo

Metanálise317
Estudo em Animais116
Estudo Laboratorial60
Ensaio Clínico46
Ensaio Clínico Duplo-Cego29
Metanálise Clínica2

Direção do resultado

Favorável453
Inconclusivo82
Desfavorável35

Por década

1990s1
2000s41
2010s187
2020s341

570 estudos

Filtrar e buscar no acervo →

Esta página mostra 306 dos 570 estudos indexados sobre o tema, dos mais recentes aos mais antigos. Abra o acervo com este filtro para percorrer todos, ou baixe a lista completa em JSON e CSV.

  1. 2024

    A systematic review of novel cannabinoids and their targets: Insights into the significance of structure in activity

    InconclusivoMetanáliseAnandamida (AEA)2-Araquidonoilglicerol (2-AG)+3
  2. 2024

    Cannabinoid Analgesia in Postoperative Pain Management: From Molecular Mechanisms to Clinical Reality

    InconclusivoMetanáliseDorDor — AgudaAnandamida (AEA)Tetraidrocanabinol (THC)+7
  3. 2024

    Cold-induced changes in plasma signaling lipids are associated with a healthier cardiometabolic profile independently of brown adipose tissue

    FavorávelEnsaio ClínicoObesidadeDiabetesSíndrome MetabólicaExposição ao Frio
  4. 2024

    Cyclic vomiting syndrome: Future clinical and research priorities for: Special supplement/proceedings of 3rd international symposium

    DesfavorávelMetanáliseNáusea e VômitoSíndrome da Hiperêmese Canabinoide
  5. 2024

    Dietary linoleic acid lowering alone does not lower arachidonic acid or endocannabinoids among women with overweight and obesity: A randomized, controlled trial

  6. 2024

    Editorial: Insights on cannabinoid translational science and medicine: the endocannabinoidome as a target for clinical practice

    FavorávelMetanáliseAnandamida (AEA)Tetraidrocanabinol (THC)+9
  7. 2024

    Effects of Cannabidiol and Delta-9-Tetrahydrocannabinol on Plasma Endocannabinoid Levels in Healthy Volunteers: A Randomized Double-Blind Four-Arm Crossover Study

    InconclusivoEnsaio Clínico Duplo-CegoEfeitos Adversos da CannabisAnandamida (AEA)Tetraidrocanabinol (THC)+2
  8. 2024

    Endocannabinoid Hydrolase Inhibitors: Potential Novel Anxiolytic Drugs

    FavorávelMetanáliseAnsiedadeAnandamida (AEA)2-Araquidonoilglicerol (2-AG)+4
  9. 2024

    Endocannabinoid levels in female-sexed individuals with diagnosed depression: a systematic review

    InconclusivoMetanáliseAnsiedadeDepressãoPsicose
  10. 2024

    Evaluating the Impact of Probiotic Therapy on the Endocannabinoid System, Pain, Sleep and Fatigue: A Randomized, Double-Blind, Placebo-Controlled Trial in Dancers

  11. 2024

    Low vitamin D levels are linked with increased cardiovascular disease risk in young adults: a sub-study and secondary analyses from the ACTIBATE randomized controlled trial

    FavorávelEnsaio ClínicoInflamaçãoDoenças Cardiovasculares (DCV)Síndrome Metabólica+1
  12. 2024

    Moving to Improve Mental Health - The Role of Exercise in Cognitive Function: A Narrative Review

    FavorávelMetanáliseAnsiedadeDepressãoDisfunção CognitivaExercício Físico
  13. 2024

    Neurolipidomic insights into anxiety disorders: Uncovering lipid dynamics for potential therapeutic advances

  14. 2024

    Nutrient composition of different energy-restricted diets determines plasma endocannabinoid profiles and adipose tissue DAGL-α expression; a 12-week randomized controlled trial in subjects with abdominal obesity

  15. 2024

    Oxytocin alleviates periodontitis in adult rats

    FavorávelEstudo em AnimaisInflamaçãoDoença Periodontal
  16. 2024

    Patent review of cannabinoid receptor type 2 (CB2R) modulators (2016-present)

  17. 2024

    Re-evaluation of the cardioprotective effects of cannabinoids against ischemia-reperfusion injury according to the IMproving Preclinical Assessment of Cardioprotective Therapies (IMPACT) criteria

    InconclusivoMetanáliseDoenças Cardiovasculares (DCV)Lesão de Reperfusão
  18. 2024

    Systematic review: the impact of maternal pre-and postnatal cannabis use on the behavioral and emotional regulation in early childhood

  19. 2024

    The circulating and central endocannabinoid system in obesity and weight loss

    InconclusivoMetanáliseObesidadeAnandamida (AEA)2-Araquidonoilglicerol (2-AG)
  20. 2024

    The Clinical Translation of α-humulene - A Scoping Review

    FavorávelMetanáliseCâncerInflamaçãoEstresse Oxidativo+5
  21. 2024

    The Therapeutic Potential of Cannabidiol in Revolutionising Opioid Use Disorder Management

  22. 2024

    The Use of Compounds Derived from Cannabis sativa in the Treatment of Epilepsy, Painful Conditions, and Neuropsychiatric and Neurodegenerative Disorders

    FavorávelMetanáliseDorInflamaçãoEpilepsia+3
  23. 2023

    A randomized, double-blind, placebo-controlled, repeated-dose pilot study of the safety, tolerability, and preliminary effects of a cannabidiol (CBD)- and cannabigerol (CBG)-based beverage powder to support recovery from delayed onset muscle soreness (DOMS)

    FavorávelEnsaio Clínico Duplo-CegoDorDor — AgudaCanabigerol (CBG)
  24. 2023

    Additive or synergistic analgesic effect of metamizole on standard pain treatment at home after arthroscopic shoulder surgery: A randomised controlled superiority trial

    InconclusivoEnsaio Clínico Duplo-CegoDorInflamaçãoDependência — Opioides+1
  25. 2023

    Almond Consumption for 8 Weeks Altered Host and Microbial Metabolism in Comparison to a Control Snack in Young Adults

  26. 2023

    Biobehavioral Interactions between Endocannabinoid and Hypothalamic-pituitary-adrenal Systems in Psychosis: A Systematic Review

    InconclusivoMetanáliseDependência — CannabisPsicoseTranstornos de Comportamento+1
  27. 2023

    Cannabidiol: Bridge between Antioxidant Effect, Cellular Protection, and Cognitive and Physical Performance

  28. 2023

    Cannabinoid Hyperemesis Syndrome in a 23-Year-Old Woman with Uncontrolled Type 1 Diabetes Mellitus

    DesfavorávelMetanáliseDorEfeitos Adversos da CannabisDor — Crônica+5
  29. 2023

    Cannabinoid receptor type 1 (CB1R) inhibits hypothalamic leptin signaling via β-arrestin1 in complex with TC-PTP and STAT3

  30. 2023

    CB1 receptor expression and signaling are required for dexamethasone-induced aversive memory consolidation

  31. 2023

    Does the "Entourage Effect" in Cannabinoids Exist? A Narrative Scoping Review

    FavorávelEstudo LaboratorialTetraidrocanabinol (THC)
  32. 2023

    Effects of CB1R inverse agonist, INV-202, in patients with features of metabolic syndrome. A randomized, placebo-controlled, double-blind phase 1b study

    FavorávelEnsaio Clínico Duplo-CegoObesidadeSíndrome Metabólica
  33. 2023

    Efficacy and safety of olorinab, a full agonist of the cannabinoid receptor 2, for the treatment of abdominal pain in patients with irritable bowel syndrome: Results from a phase 2b randomized placebo-controlled trial (CAPTIVATE)

    FavorávelEnsaio Clínico Duplo-CegoDorDor — CrônicaSíndrome do Intestino Irritável+1
  34. 2023

    Endocannabinoid 2-Arachidonoylglycerol Synthesis and Metabolism at Neuronal Nuclear Matrix Fractions Derived from Adult Rat Brain Cortex

    FavorávelEstudo LaboratorialEstresse OxidativoAnandamida (AEA)2-Araquidonoilglicerol (2-AG)+2
  35. 2023

    Endocannabinoid System and Exogenous Cannabinoids in Depression and Anxiety: A Review

  36. 2023

    Endocannabinoid system components as potential neuroimmune therapeutic targets in tinnitus

    FavorávelMetanáliseZumbidoCanabinoide Sintético (não especificado)
  37. 2023

    Exploring the therapeutic potential of an antinociceptive and anti-inflammatory peptide from wasp venom

    FavorávelEstudo em AnimaisDorInflamaçãoDor — CrônicaCanabinoides Sintéticos AM-x+4
  38. 2023

    Induction of Anxiety-Like Phenotypes by Knockdown of Cannabinoid Type-1 Receptors in the Amygdala of Marmosets

    DesfavorávelEstudo em AnimaisAnsiedadeDepressãoDisfunção Cognitiva+2
  39. 2023

    Involvement of cannabinoid receptors and neuroinflammation in early sepsis: Implications for posttraumatic stress disorder

  40. 2023

    Measuring white matter microstructure in 1,457 cannabis users and 1,441 controls: A systematic review of diffusion-weighted MRI studies

  41. 2023

    Molecular Insights into GPCR Mechanisms for Drugs of Abuse

  42. 2023

    N-oleoyl glycine and N-oleoyl alanine attenuate alcohol self-administration and preference in mice

  43. 2023

    New Drugs for Managing Acne

    FavorávelMetanáliseInflamaçãoInfecções BacterianasAcne
  44. 2023

    Prebiotics Plus Probiotics May Favorably Impact on Gut Permeability, Endocannabinoid Receptors, and Inflammatory Biomarkers in Patients with Coronary Artery Diseases: A Clinical Trial

  45. 2023

    Prenatal Exposure to Δ9-Tetrahydrocannabinol Affects Hippocampus-Related Cognitive Functions in the Adolescent Rat Offspring: Focus on Specific Markers of Neuroplasticity

  46. 2023

    Prenatal THC exposure induces long-term, sex-dependent cognitive dysfunction associated with lipidomic and neuronal pathology in the prefrontal cortex-hippocampal network

  47. 2023

    Rabies: Presentation, case management and therapy

    FavorávelMetanáliseRaiva
  48. 2023

    Regulatory role of the endocannabinoid system on glial cells toward cognitive function in Alzheimer's disease: A systematic review and meta-analysis of animal studies

  49. 2023

    Reversible cerebral vasoconstriction syndrome associated with probable drug poisoning

    DesfavorávelMetanáliseEfeitos Adversos da CannabisDepressãoEpilepsia+3
  50. 2023

    Saffron (Crocus sativus) and its constituents for pain management: A review of current evidence

    FavorávelMetanáliseDorEstresse OxidativoGestação+4
  51. 2023

    Striatonigral direct pathway 2-arachidonoylglycerol contributes to ethanol effects on synaptic transmission and behavior

  52. 2023

    Structural organisation of perisomatic inhibition in the mouse medial prefrontal cortex

    InconclusivoEstudo em AnimaisDisfunção CognitivaDoenças Neurodegenerativas
  53. 2023

    Structure-Based Virtual Screening and Molecular Dynamics Simulation Assessments of Depsidones as Possible Selective Cannabinoid Receptor Type 2 Agonists

    FavorávelEstudo LaboratorialDorInflamaçãoInfecções Bacterianas+4
  54. 2023

    Sudden Cardiac Arrest in Patient With Ventricular Septal Defect and Marijuana Consumption: A Case Report and Review of Literature

  55. 2023

    Synergetic effect of β-asarone and cannabidiol against Aβ aggregation in vitro and in vivo

    FavorávelEstudo LaboratorialInflamaçãoEstresse OxidativoDoenças Neurodegenerativas+2
  56. 2023

    Systematic review and rationale of using psychedelics in the treatment of cannabis use disorder

  57. 2023

    Systemic Changes in Endocannabinoids and Endocannabinoid-like Molecules in Response to Partial Nephrectomy-Induced Ischemia in Humans

    FavorávelEnsaio ClínicoInsuficiência RenalAnandamida (AEA)Palmitoiletanolamida (PEA)+1
  58. 2023

    The Effects of Peripubertal THC Exposure in Neurodevelopmental Rat Models of Psychopathology

  59. 2023

    The endogenous cannabinoid system modulates male sexual behavior expression

  60. 2023

    The use of cannabidiol as a novel treatment for oral stereotypic behaviour (crib-biting) in a horse

    FavorávelEstudo em AnimaisDorInflamaçãoAnsiedade+13
  61. 2023

    Therapeutic effect of cannabidiol on myocardial arachidonic acid content in various lipid fractions in a rat model of obesity

    FavorávelEstudo em AnimaisInflamaçãoDoenças Cardiovasculares (DCV)Estresse Oxidativo+4
  62. 2022

    (Wh)olistic (E)ndocannabinoidome-Microbiome-Axis Modulation through (N)utrition (WHEN) to Curb Obesity and Related Disorders

  63. 2022

    A review on structurally diversified synthesized molecules as monoacylglycerol lipase inhibitors and their therapeutic uses

    InconclusivoMetanáliseDorCâncerInflamaçãoMonoacilglicerol Lipase (MAGL)+5
  64. 2022

    A Review on the Bioactivity of Cannabinoids on Zebrafish Models: Emphasis on Neurodevelopment

    FavorávelMetanáliseDorCâncerAnsiedadeAnandamida (AEA)Tetraidrocanabinol (THC)+25
  65. 2022

    A survey of medical cannabis use during perimenopause and postmenopause

    InconclusivoMetanáliseAnsiedadeInsônia e Distúrbios do SonoMenopausa+1
  66. 2022

    Abstinence from Chronic Methylphenidate Exposure Modifies Cannabinoid Receptor 1 Levels in the Brain in a Dose-dependent Manner

    InconclusivoEstudo em AnimaisTranstornos de ComportamentoTDA e TDAH
  67. 2022

    Acaricidal and anthelmintic efficacy of Ocimum basilicum essential oil and its major constituents estragole and linalool, with insights on acetylcholinesterase inhibition

    FavorávelEstudo em AnimaisVerminoses
  68. 2022

    Activation of cannabinoid receptors in breast cancer cells improves osteoblast viability in cancer-bone interaction model while reducing breast cancer cell survival and migration

  69. 2022

    Activation of CB1 pathway in the perirhinal cortex is necessary but not sufficient for destabilization of contextual fear memory in rats

    FavorávelEstudo em AnimaisDisfunção Cognitiva
  70. 2022

    Activation of GPR55 attenuates cognitive impairment, oxidative stress, neuroinflammation, and synaptic dysfunction in a streptozotocin-induced Alzheimer's mouse model

  71. 2022

    Activation of the endocannabinoid system mediates cardiac hypertrophy induced by rosiglitazone

  72. 2022

    Acute and long-term exercise differently modulate plasma levels of oxylipins, endocannabinoids, and their analogues in young sedentary adults: A sub-study and secondary analyses from the ACTIBATE randomized controlled-trial

  73. 2022

    Age-related changes in CB1 receptor expression and function and the behavioral effects of cannabinoid receptor ligands

    InconclusivoEstudo em AnimaisTranstornos de Comportamento
  74. 2022

    Alteration of osteoclast activity in childhood cancer survivors: Role of iron and of CB2/TRPV1 receptors

  75. 2022

    Ameliorative effects of ribes rubrum oil against gastric ulcers caused by indomethacin in experimental models

    FavorávelEstudo em AnimaisInflamaçãoRefluxo GastroesofágicoÚlcera Gástrica
  76. 2022

    Anandamide Hydrolysis Inhibition Reverses the Long-Term Behavioral and Gene Expression Alterations Induced by MK-801 in Male Rats: Differential CB1 and CB2 Receptor-Mediated Effects

    FavorávelEstudo em AnimaisDisfunção CognitivaPsicoseEsquizofreniaAnandamida (AEA)+1
  77. 2022

    Anti-inflammatory effects of lavender and eucalyptus essential oils on the in vitro cell culture model of bladder pain syndrome using T24 cells

    FavorávelEstudo LaboratorialInflamaçãoCistite
  78. 2022

    Anticancer activity of linalool: comparative investigation of ultrastructural changes and apoptosis in breast cancer cells

    FavorávelEstudo LaboratorialCâncerCâncer — Mama
  79. 2022

    Antispasmodic Effect of Bergamot Essential Oil on Rat Isolated Gut Tissues

    FavorávelEstudo LaboratorialInflamaçãoSíndrome do Intestino Irritável
  80. 2022

    Association of cannabinoid receptor modulation with normal and abnormal skeletal remodelling: A systematic review and meta-analysis of in vitro, in vivo and human studies

  81. 2022

    Biological effects of cannabidiol on human cancer cells: Systematic review of the literature

    InconclusivoMetanáliseCâncerInflamaçãoCâncer — MamaCanabinol (CBN)+12
  82. 2022

    Biomarkers and treatments for mood disorders encompassing the neurosteroid and endocannabinoid systems

    FavorávelMetanáliseAnsiedadeDepressãoGestaçãoPalmitoiletanolamida (PEA)+3
  83. 2022

    Cannabidiol as a personalized treatment for anxiety: clinical cases in Mexico

  84. 2022

    Cannabidiol Enhances Microglial Beta-Amyloid Peptide Phagocytosis and Clearance via Vanilloid Family Type 2 Channel Activation

    FavorávelEstudo LaboratorialDoenças NeurodegenerativasDoença de Alzheimer
  85. 2022

    Cannabidiol for the treatment of autism spectrum disorder: hope or hype?

    FavorávelMetanáliseAnsiedadeDepressãoEpilepsia+4
  86. 2022

    Cannabidiol in the context of substance use disorder treatment: A systematic review

  87. 2022

    Cannabidiol Promotes Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells in the Inflammatory Microenvironment via the CB2-dependent p38 MAPK Signaling Pathway

    FavorávelEstudo em AnimaisInflamaçãoOsteoporoseFraturas ÓsseasCanabinoides Sintéticos AM-x+1
  88. 2022

    Cannabigerol (CBG) attenuates mechanical hypersensitivity elicited by chemotherapy-induced peripheral neuropathy

  89. 2022

    Cannabinoid 1 and mu-Opioid Receptor Agonists Synergistically Inhibit Abdominal Pain and Lack Side Effects in Mice

  90. 2022

    Cannabinoid and vanilloid pathways mediate opposing forms of synaptic plasticity in corticotropin-releasing hormone neurons

    FavorávelEstudo LaboratorialEstresse Oxidativo2-Araquidonoilglicerol (2-AG)
  91. 2022

    Cannabinoid CB 2 Receptors Modulate Microglia Function and Amyloid Dynamics in a Mouse Model of Alzheimer's Disease

    FavorávelEstudo em AnimaisInflamaçãoDoenças NeurodegenerativasDoença de Alzheimer
  92. 2022

    Cannabinoid CB1 Receptor Involvement in the Actions of CBD on Anxiety and Coping Behaviors in Mice

    FavorávelEstudo em AnimaisAnsiedadeDepressãoDisfunção CognitivaCanabinoides Sintéticos SR-x+1
  93. 2022

    Cannabinoid receptor 2 engagement promotes group 2 innate lymphoid cell expansion and enhances airway hyperreactivity

    FavorávelEstudo em AnimaisInflamaçãoAsma
  94. 2022

    Cannabinoid receptor availability modulates the magnitude of dopamine release in vivo in the human reward system: A preliminary multitracer positron emission tomography study

    FavorávelEnsaio ClínicoEsquizofreniaDependência — Estimulantes
  95. 2022

    Cannabinoid treatments for anxiety: A systematic review and consideration of the impact of sleep disturbance

    FavorávelMetanáliseAnsiedadeInsônia e Distúrbios do Sono
  96. 2022

    Cannabinoids as anticancer drugs: current status of preclinical research

  97. 2022

    Cannabinoids as Glial Cell Modulators in Ischemic Stroke: Implications for Neuroprotection

  98. 2022

    Cannabinoids in rheumatology: Friend, foe or a bystander?

  99. 2022

    Cannabinoids induce functional Tregs by promoting tolerogenic DCs via autophagy and metabolic reprograming

  100. 2022

    Cannabinoids receptors in Covid-19: Perpetrators and victims

    FavorávelMetanáliseInflamaçãoCOVID-19Estresse+2
  101. 2022

    Cannabis as a potential compound against various malignancies, legal aspects, advancement by exploiting nanotechnology and clinical trials

    FavorávelMetanáliseDorCâncerDor — Oncológica
  102. 2022

    Cannabis Biomolecule Effects on Cancer Cells and Cancer Stem Cells: Cytotoxic, Anti-Proliferative, and Anti-Migratory Activities

    FavorávelMetanáliseCâncerCâncer — Cérebro
  103. 2022

    Cannabis in Parkinson's Disease - the patient's perspective versus clinical trials: a systematic literature review

    DesfavorávelMetanálise ClínicaDorInflamaçãoAnsiedadeAnandamida (AEA)2-Araquidonoilglicerol (2-AG)+5
  104. 2022

    Cannabis Use and the Endocannabinoid System: A Clinical Perspective

  105. 2022

    Cannabis use as a factor of lower corpulence in hepatitis C-infected patients: results from the ANRS CO22 Hepather cohort

    FavorávelMetanáliseInflamaçãoObesidadeDiabetesTetraidrocanabivarina (THCV)+3
  106. 2022

    Cannabis Use in Autism: Reasons for Concern about Risk for Psychosis

    InconclusivoMetanáliseEpilepsiaPsicoseEsquizofreniaTetraidrocanabinol (THC)+3
  107. 2022

    Cannabis-Based Products for the Treatment of Skin Inflammatory Diseases: A Timely Review

    FavorávelMetanáliseDorCâncerInflamaçãoAnandamida (AEA)Tetraidrocanabinol (THC)+28
  108. 2022

    CB1 receptor antagonist AM4113 reverts the effects of cannabidiol on cue and stress-induced reinstatement of cocaine-seeking behaviour in mice

  109. 2022

    CB1R, CB2R and TRPV1 expression and modulation in in vivo, animal glaucoma models: A systematic review

  110. 2022

    CBD activation of TRPV1 induces oxidative signaling and subsequent ER stress in breast cancer cell lines

    FavorávelEstudo LaboratorialCâncerEstresse OxidativoCâncer — Mama
  111. 2022

    Cell-Type Specific Deletion of CB2 Cannabinoid Receptors in Dopamine Neurons Induced Hyperactivity Phenotype: Possible Relevance to Attention-Deficit Hyperactivity Disorder

    InconclusivoEstudo em AnimaisTDA e TDAH
  112. 2022

    Changes in the expression of endocannabinoid system components in an experimental model of chemotherapy-induced peripheral neuropathic pain: Evaluation of sex-related differences

  113. 2022

    Circulating endocannabinoids and genetic polymorphisms as predictors of posttraumatic stress disorder symptom severity: heterogeneity in a community-based cohort

    InconclusivoEnsaio ClínicoTEPTAnandamida (AEA)2-Araquidonoilglicerol (2-AG)+1
  114. 2022

    Cutaneous Squamous Cell Carcinoma and Lichen Simplex Chronicus Successfully Treated with Topical Cannabinoid Oil: A Case Report and Summary of Cannabinoids in Dermatology

  115. 2022

    Decreasing sperm quality in mice subjected to chronic cannabidiol exposure: New insights of cannabidiol-mediated male reproductive toxicity

    DesfavorávelEstudo em AnimaisEstresse OxidativoInfertilidade MasculinaLibido+1
  116. 2022

    Deprogramming metabolism in pancreatic cancer with a bi-functional GPR55 inhibitor and biased β2 adrenergic agonist

    FavorávelEstudo LaboratorialCâncerCâncer — MamaCâncer — Cérebro+2
  117. 2022

    Differential Effects of D9 Tetrahydrocannabinol (THC)- and Cannabidiol (CBD)-Based Cannabinoid Treatments on Macrophage Immune Function In Vitro and on Gastrointestinal Inflammation in a Murine Model

  118. 2022

    Differential expression of the neuronal CB1 cannabinoid receptor in the hippocampus of male Ts65Dn Down syndrome mouse model

    FavorávelEstudo em AnimaisSíndrome de DownAnandamida (AEA)2-Araquidonoilglicerol (2-AG)+3
  119. 2022

    Does Cannabidiol Have a Benefit as a Supportive Care Drug in Cancer?

  120. 2022

    Dynamic Changes in the Endocannabinoid System during the Aging Process: Focus on the Middle-Age Crisis

    FavorávelEstudo em AnimaisLongevidadeAnandamida (AEA)2-Araquidonoilglicerol (2-AG)
  121. 2022

    Early Blockade of CB1 Receptors Ameliorates Schizophrenia-like Alterations in the Neurodevelopmental MAM Model of Schizophrenia

  122. 2022

    Effects of endocannabinoid system modulation on social behaviour: A systematic review of animal studies

  123. 2022

    Effects of non‐steroidal anti‐inflammatory drugs and other eicosanoid pathway modifiers on antiviral and allergic responses: EAACI task force on eicosanoids consensus report in times of COVID‐19

  124. 2022

    Effects of Rare Phytocannabinoids on the Endocannabinoid System of Human Keratinocytes

    FavorávelEstudo LaboratorialDoenças de PeleAnandamida (AEA)2-Araquidonoilglicerol (2-AG)+7
  125. 2022

    Effects of rich cannabidiol oil on behavioral disturbances in patients with dementia: A placebo controlled randomized clinical trial

    FavorávelEnsaio Clínico Duplo-CegoAnandamida (AEA)Tetraidrocanabinol (THC)+3
  126. 2022

    Endocannabinoid Modulation in Neurodegenerative Diseases: In Pursuit of Certainty

  127. 2022

    Endocannabinoid signaling in glioma

  128. 2022

    Endocannabinoid signalling/cannabinoid receptor 2 is involved in icariin-mediated protective effects against bleomycin-induced pulmonary fibrosis

    FavorávelEstudo em AnimaisFibroseDPOCFibrose — Pulmonar
  129. 2022

    Endocannabinoid system contributions to sex-specific adolescent neurodevelopment

    InconclusivoMetanáliseDisfunção CognitivaTranstornos de Comportamento
  130. 2022

    Endocannabinoids and aging-Inflammation, neuroplasticity, mood and pain

  131. 2022

    Endothelial dysfunction and angiogenesis: what is missing from COVID-19 and cannabidiol story?

  132. 2022

    Evidence-based Potential Therapeutic Applications of Cannabinoids in Wound Management

    FavorávelMetanáliseInflamaçãoCicatrização
  133. 2022

    Exploring the endocannabinoidome in genetically obese (ob/ob) and diabetic (db/db) mice: Links with inflammation and gut microbiota

  134. 2022

    Expression and Functions of the CB 2 Receptor in Human Leukocytes

  135. 2022

    Fatty Acid Amide Hydrolase Deficiency Is Associated with Deleterious Cardiac Effects after Myocardial Ischemia and Reperfusion in Mice

  136. 2022

    Footshock-Induced Abstinence from Compulsive Methamphetamine Self-administration in Rat Model Is Accompanied by Increased Hippocampal Expression of Cannabinoid Receptors (CB1 and CB2)

  137. 2022

    G Protein-Coupled Receptors in Osteoarthritis

  138. 2022

    Gene Expression Analysis of the Endocannabinoid System in Presymptomatic APP/PS1 Mice

  139. 2022

    Immunomodulatory effect of Linalool (Lin) against CCl 4 -induced hepatotoxicity and oxidative damage in rats

    FavorávelEstudo em AnimaisInflamaçãoHepatiteInsuficiência Hepática+2
  140. 2022

    Immunomodulatory Role of CB2 Receptors in Emotional and Cognitive Disorders

  141. 2022

    Impact of cyclooxygenase-2 inhibition on cannabis withdrawal and circulating endocannabinoids in daily cannabis smokers

  142. 2022

    Impact of the cannabinoid system in Alzheimer's diseases

    FavorávelMetanáliseDoenças NeurodegenerativasDoença de AlzheimerDemência
  143. 2022

    Impact of the Endocannabinoid System on Bone Formation and Remodeling in p62 KO Mice

    InconclusivoEstudo em AnimaisOsteoporoseCanabinoides Sintéticos JWH-x
  144. 2022

    Impact of Δ9-Tetrahydrocannabinol on Rheumatoid Arthritis Synovial Fibroblasts Alone and in Co-Culture with Peripheral Blood Mononuclear Cells

    FavorávelEstudo LaboratorialInflamaçãoArtriteArtrite — ReumatoideTHC Farmacêutico+1
  145. 2022

    Improved cognition impairment by activating cannabinoid receptor type 2: Modulating CREB/BDNF expression and impeding TLR-4/NFκBp65/M1 microglia signaling pathway in D-galactose-injected ovariectomized rats

  146. 2022

    In it together? The case for endocannabinoid–noradrenergic interactions in fear extinction

  147. 2022

    Increased expression of CB2 receptor in the intestinal biopsies of children with inflammatory bowel disease

  148. 2022

    Influence of N-Arachidonoyl Dopamine and N-Docosahexaenoyl Dopamine on the Expression of Neurotrophic Factors in Neuronal Differentiated Cultures of Human Induced Pluripotent Stem Cells under Conditions of Oxidative Stress

  149. 2022

    Inhalation of low-dose basil (Ocimum basilicum) essential oil improved cardiovascular health and plasma lipid markers in high fat diet-induced obese rats

    FavorávelEstudo em AnimaisDoenças Cardiovasculares (DCV)ObesidadeSíndrome Metabólica+1
  150. 2022

    Inhibiting Endocannabinoid Hydrolysis as Emerging Analgesic Strategy Targeting a Spectrum of Ion Channels Implicated in Migraine Pain

    FavorávelMetanáliseEnxaquecaAnandamida (AEA)2-Araquidonoilglicerol (2-AG)+4
  151. 2022

    Inhibiting the endocannabinoid degrading enzymes FAAH and MAGL during zebrafish embryogenesis alters sensorimotor function

  152. 2022

    Interactions of Noradrenergic, Glucocorticoid and Endocannabinoid Systems Intensify and Generalize Fear Memory Traces

    DesfavorávelEstudo em AnimaisTEPTCanabinoides Sintéticos AM-x
  153. 2022

    Interplay of gut microbiome, fatty acids, and the endocannabinoid system in regulating development, progression, immunomodulation, and chemoresistance of cancer

    FavorávelMetanáliseCâncerMicrobioma
  154. 2022

    Interpreting Clinical Trials With Omega-3 Supplements in the Context of Ancestry and FADS Genetic Variation

  155. 2022

    Investigation of the Effects of the Endogenous Cannabinoid Anandamide on Luminal A Breast Cancer Cell Line MCF-7

    FavorávelEstudo LaboratorialCâncerCâncer — MamaAnandamida (AEA)
  156. 2022

    Involvement of the cannabinoid system in chronic inflammatory intestinal diseases: opportunities for new therapies

  157. 2022

    Lavandula dentata L.: Phytochemical Analysis, Antioxidant, Antifungal and Insecticidal Activities of Its Essential Oil

    FavorávelEstudo LaboratorialInflamaçãoEstresse OxidativoInfecções Fúngicas
  158. 2022

    Mechanisms of Cannabidiol (CBD) in Cancer Treatment: A Review

    FavorávelMetanáliseDorCâncerInflamaçãoTetraidrocanabinol (THC)Canabigerol (CBG)+13
  159. 2022

    Medicinal Herbs in the Relief of Neurological, Cardiovascular, and Respiratory Symptoms after COVID-19 Infection A Literature Review

    FavorávelMetanáliseInflamaçãoAnsiedadeDoenças Cardiovasculares (DCV)+11
  160. 2022

    Mitochondrial Localization of CB1 in Progesterone-producing Cells of Ovarian Interstitial Glands of Adult Mice

    FavorávelEstudo Laboratorial
  161. 2022

    Modulation of Endocannabinoid System Components in Depression: Pre-Clinical and Clinical Evidence

    InconclusivoMetanáliseAnsiedadeDepressãoAnandamida (AEA)2-Araquidonoilglicerol (2-AG)+7
  162. 2022

    Modulation of Morphine Analgesia, Antinociceptive Tolerance, and Mu-Opioid Receptor Binding by the Cannabinoid CB2 Receptor Agonist O-1966

  163. 2022

    Molecular Pathways of the Therapeutic Effects of Ayahuasca, a Botanical Psychedelic and Potential Rapid-Acting Antidepressant

    FavorávelMetanáliseDepressãoAyahuasca
  164. 2022

    Mutual Links between the Endocannabinoidome and the Gut Microbiome, with Special Reference to Companion Animals: A Nutritional Viewpoint

  165. 2022

    Neuroplastic alterations in cannabinoid receptors type 1 (CB1) in animal models of epileptic seizures

    FavorávelMetanáliseEpilepsia
  166. 2022

    Non-psychotropic Cannabis sativa L. phytocomplex modulates microglial inflammatory response through CB2 receptors-, endocannabinoids-, and NF-κB-mediated signaling

    FavorávelEstudo LaboratorialInflamaçãoDoenças NeurodegenerativasOutros Compostos Relacionados
  167. 2022

    Olfactory Stimulation with Volatile Aroma Compounds of Basil ( Ocimum basilicum L.) Essential Oil and Linalool Ameliorates White Fat Accumulation and Dyslipidemia in Chronically Stressed Rats

    FavorávelEstudo em AnimaisInflamaçãoDoenças Cardiovasculares (DCV)Síndrome Metabólica+3
  168. 2022

    Opioid-sparing effect of cannabinoids for analgesia: an updated systematic review and meta-analysis of preclinical and clinical studies

  169. 2022

    Orchestration of the circadian clock and its association with Alzheimer's disease: Role of endocannabinoid signaling

  170. 2022

    Oxytocin acts centrally in the brain to improve leaky gut through the vagus nerve and a cannabinoid signaling in rats

    FavorávelEstudo em AnimaisAutismoSíndrome do Intestino IrritávelGastroparesia
  171. 2022

    Peripheral Cannabinoid-1 Receptor Blockade Ameliorates Cystitis Severity

    FavorávelEstudo em AnimaisCistiteCanabinoide Sintético (não especificado)
  172. 2022

    Pharmacological Activation of GPR55 Improved Cognitive Impairment Induced by Lipopolysaccharide in Mice

  173. 2022

    Pharmacological Aspects and Biological Effects of Cannabigerol and Its Synthetic Derivatives

  174. 2022

    Phytocannabinoids and Cannabis-Based Products as Alternative Pharmacotherapy in Neurodegenerative Diseases: From Hypothesis to Clinical Practice

  175. 2022

    Phytocannabinoids regulate inflammation in IL-1β-stimulated human gingival fibroblasts

    FavorávelEstudo LaboratorialDorInflamaçãoDoença PeriodontalCanabigerol (CBG)Canabidivarina (CBDV)+1
  176. 2022

    Potential Utility of Cannabidiol in Stress-Related Disorders

    FavorávelMetanáliseAnsiedadeTranstornos de ComportamentoTEPT
  177. 2022

    Prefrontal cortical distribution of muscarinic M2 and cannabinoid-1 (CB1) receptors in adult male mice with or without chronic adolescent exposure to Δ9-tetrahydrocannabinol

  178. 2022

    Recent Advances on Type-2 Cannabinoid (CB2) Receptor Agonists and Their Therapeutic Potential

    FavorávelMetanálise
  179. 2022

    Rice Bran Lipidome Identifies Novel Phospholipids, Glycolipids, and Oxylipins with Roles in Lipid Metabolism of Hypercholesterolemic Children

  180. 2022

    Role of Cannabinoids in Various Diseases: A Review

    FavorávelMetanáliseDorInflamaçãoDor — Crônica+10
  181. 2022

    Role of cannabis in inflammatory bowel diseases

  182. 2022

    Role of the endocannabinoid system in the pathophysiology of endometriosis and therapeutic implications

  183. 2022

    Role of the Endocannabinoid System in the Regulation of Intestinal Homeostasis

  184. 2022

    Sebaceous immunobiology - skin homeostasis, pathophysiology, coordination of innate immunity and inflammatory response and disease associations

  185. 2022

    Spinal cannabinoid CB1 or CB2 receptors activation attenuates mechanical allodynia in streptozotocin-induced diabetic rats

  186. 2022

    Structure-activity relationships for 5F-MDMB-PICA and its 5F-pentylindole analogs to induce cannabinoid-like effects in mice

  187. 2022

    Synaptic changes induced by cannabinoid drugs and cannabis use disorder

  188. 2022

    Systematic literature review of human studies assessing the efficacy of cannabidiol for social anxiety

    FavorávelMetanáliseAnsiedade
  189. 2022

    Targeting the endocannabinoid system for the treatment of abdominal pain in irritable bowel syndrome

  190. 2022

    Targeting the Endocannabinoid System in the Treatment of Posttraumatic Stress Disorder: A Promising Case of Preclinical-Clinical Translation?

    FavorávelMetanáliseTEPTCanabinoide Sintético (não especificado)
  191. 2022

    Targeting the Endocannabinoid System: From the Need for New Therapies to the Development of a Promising Strategy. What About Pancreatic Cancer?

  192. 2022

    Targeting the Endocannabinoidome in Pancreatic Cancer

  193. 2022

    Terpenes and terpenoids as main bioactive compounds of essential oils, their roles in human health and potential application as natural food preservatives

    FavorávelMetanáliseCâncerInflamaçãoEstresse Oxidativo+1
  194. 2022

    The acute effects of cannabidiol on emotional processing and anxiety: a neurocognitive imaging study

  195. 2022

    The Autism–Psychosis Continuum Conundrum: Exploring the Role of the Endocannabinoid System

  196. 2022

    The cannabinoid receptor I (CB1) enhanced the osteogenic differentiation of BMSCs by rescue impaired mitochondrial metabolism function under inflammatory condition

    FavorávelEstudo LaboratorialDorInflamaçãoDor — Aguda+2
  197. 2022

    The Cannabis-Induced Epigenetic Regulation of Genes Associated with Major Depressive Disorder

    FavorávelMetanáliseDepressãoEpilepsiaPsicose+3
  198. 2022

    The effect of β-caryophyllene on food addiction and its related behaviors: A randomized, double-blind, placebo-controlled trial

    FavorávelEnsaio Clínico Duplo-CegoAnsiedadeDepressãoObesidade+1
  199. 2022

    The effects of acute alcohol administration on circulating endocannabinoid levels in humans

  200. 2022

    The Effects of Cannabidiol and δ-9-Tetrahydrocannabinol in Social Cognition: A Naturalistic Controlled Study

    DesfavorávelEnsaio Clínico Duplo-CegoAnsiedadeDisfunção CognitivaPsicoseTetraidrocanabinol (THC)+5
  201. 2022

    The Endocannabinoid System and Physical Activity—A Robust Duo in the Novel Therapeutic Approach against Metabolic Disorders

  202. 2022

    The Endocannabinoid System as a Biomarker for Diagnostic and Therapeutic Applications in Depression and Anxiety

    InconclusivoMetanáliseAnsiedadeDepressãoAnandamida (AEA)2-Araquidonoilglicerol (2-AG)+2
  203. 2022

    The endocannabinoid system in social anxiety disorder: from pathophysiology to novel therapeutics

    FavorávelMetanáliseAnsiedadeCanabinoide Sintético (não especificado)
  204. 2022

    The endocannabinoids anandamide and 2-arachidonoylglycerol modulate the expression of angiogenic factors on HTR8/SVneo placental cells

    InconclusivoEstudo LaboratorialGestaçãoAnandamida (AEA)2-Araquidonoilglicerol (2-AG)
  205. 2022

    The interactive effects of verapamil and CB1 cannabinoid receptor antagonist/inverse agonist, AM251 on passive avoidance learning and memory in rat

    FavorávelEstudo em AnimaisTranstornos de ComportamentoCanabinoides Sintéticos AM-x
  206. 2022

    The Memory Benefit to Aged APP/PS1 Mice from Long-Term Intranasal Treatment of Low-Dose THC

    FavorávelEstudo em AnimaisInflamaçãoDisfunção CognitivaDoenças Neurodegenerativas+2
  207. 2022

    The Microbiome and Gut Endocannabinoid System in the Regulation of Stress Responses and Metabolism

    FavorávelMetanáliseObesidadeSíndrome MetabólicaMicrobioma
  208. 2022

    The Multifaceted Role of GPCRs in Amyotrophic Lateral Sclerosis: A New Therapeutic Perspective?

  209. 2022

    The regulatory and modulatory roles of TRP family channels in malignant tumors and relevant therapeutic strategies

    FavorávelMetanáliseCâncerCâncer — MetastáticoTetraidrocanabinol (THC)
  210. 2022

    The Role of Nutritional Status, Gastrointestinal Peptides, and Endocannabinoids in the Prognosis and Treatment of Children with Cancer

    InconclusivoMetanáliseDorCâncerObesidadeAnandamida (AEA)Tetraidrocanabinol (THC)+17
  211. 2022

    Therapeutic Potential of Cannabinoids on Tumor Microenvironment: A Molecular Switch in Neoplasia Transformation

  212. 2022

    Three of a Kind: Control of the Expression of Liver-Expressed Antimicrobial Peptide 2 (LEAP2) by the Endocannabinoidome and the Gut Microbiome

    FavorávelEstudo em AnimaisObesidadeDiabetesSíndrome MetabólicaMicrobioma+1
  213. 2022

    Tonic endocannabinoid signaling supports sleep through development in both sexes

  214. 2022

    Topical cannabidiol (CBD) in skin pathology – A comprehensive review and prospects for new therapeutic opportunities

    FavorávelMetanáliseDorCâncerInflamação+9
  215. 2022

    TRPV1: A Common Denominator Mediating Antinociceptive and Antiemetic Effects of Cannabinoids

  216. 2022

    What Do We Know About Medical Cannabis in Neurological Disorders and What Are the Next Steps?

  217. 2021

    A Cannabinoid 2-Selective Agonist Inhibits Allogeneic Skin Graft Rejection In Vivo

  218. 2021

    A systematic, integrative review of the effects of the endocannabinoid system on inflammation and neurogenesis in animal models of affective disorders

  219. 2021

    ACPA decreases non-small cell lung cancer line growth through Akt/PI3K and JNK pathways in vitro

  220. 2021

    Activation of GPR55 attenuates cognitive impairment and neurotoxicity in a mouse model of Alzheimer's disease induced by Aβ 1-42 through inhibiting RhoA/ROCK2 pathway

    FavorávelEstudo em AnimaisInflamaçãoDisfunção CognitivaEstresse Oxidativo+2
  221. 2021

    An overview of ongoing clinical trials assessing pharmacological therapeutic strategies to manage chemotherapy-induced peripheral neuropathy, based on preclinical studies in rodent models

    InconclusivoMetanáliseDorCâncerEstresse Oxidativo+3
  222. 2021

    Anti-Inflammatory and Pro-Autophagy Effects of the Cannabinoid Receptor CB2R: Possibility of Modulation in Type 1 Diabetes

  223. 2021

    At the heart of microbial conversations: endocannabinoids and the microbiome in cardiometabolic risk

  224. 2021

    Behavioral aspects and neurobiological properties underlying medical cannabis treatment in Shank3 mouse model of autism spectrum disorder

    FavorávelEstudo em AnimaisAutismoTetraidrocanabinol (THC)Canabinoides Sintéticos AM-x+1
  225. 2021

    Beneficial Effects of Akkermansia muciniphila Are Not Associated with Major Changes in the Circulating Endocannabinoidome but Linked to Higher Mono-Palmitoyl-Glycerol Levels as New PPARα Agonists

  226. 2021

    Cannabidiol in the prelimbic cortex modulates the comorbid condition between the chronic neuropathic pain and depression-like behaviour in rats: The role of medial prefrontal cortex 5-HT 1A and CB 1 receptors

    FavorávelEstudo em AnimaisDorDor — CrônicaDepressãoCanabinoides Sintéticos AM-x
  227. 2021

    Cannabinoid control of hippocampal functions: the where matters

  228. 2021

    Cannabinoid Receptor 1 Inhibition in Chronic Kidney Disease: A New Therapeutic Toolbox

    FavorávelMetanáliseDoença Renal Crônica
  229. 2021

    Cannabinoid receptor type 2 gene is associated with comorbidity of schizophrenia and cannabis dependence and fatty acid amide hydrolase gene is associated with cannabis dependence in the Spanish population

  230. 2021

    Cannabinoid Signaling in Auditory Function and Development

  231. 2021

    Cannabinoid signalling and effects of cannabis on the male reproductive system

    InconclusivoMetanáliseInfertilidade MasculinaLibidoDisfunção Erétil
  232. 2021

    Cannabinoids in Audiogenic Seizures: From Neuronal Networks to Future Perspectives for Epilepsy Treatment

    FavorávelMetanáliseEpilepsia
  233. 2021

    Cannabis and Autoimmunity: Possible Mechanisms of Action

  234. 2021

    Cannabis and Inflammation in HIV: A Review of Human and Animal Studies

  235. 2021

    Cannabis and the Gut-Brain Axis Communication in HIV Infection

    FavorávelMetanáliseHIV/AIDSDesequilíbrio do MicrobiomaMicrobioma
  236. 2021

    Cannabis exposure during adolescence: A uniquely sensitive period for neurobiological effects

    DesfavorávelMetanáliseEfeitos Adversos da CannabisDependência — CannabisPsicose+9
  237. 2021

    Cannabis Use and Mental Illness: Understanding Circuit Dysfunction Through Preclinical Models

  238. 2021

    CB1R and iNOS are distinct players promoting pulmonary fibrosis in Hermansky–Pudlak syndrome

    FavorávelEstudo LaboratorialInflamaçãoEstresse OxidativoFibroseAnandamida (AEA)+3
  239. 2021

    CB2 cannabinoid receptor agonist selectively inhibits the mechanosensitivity of mucosal afferents in the guinea pig bladder

    FavorávelEstudo LaboratorialDorInflamaçãoCistiteAnandamida (AEA)
  240. 2021

    Comorbid anxiety-like behavior in a rat model of colitis is mediated by an upregulation of corticolimbic fatty acid amide hydrolase

  241. 2021

    Components of the Endogenous Cannabinoid System as Potential Biomarkers for Interstitial Cystitis/Bladder Pain Syndrome

    FavorávelMetanáliseDorDor — CrônicaCistite
  242. 2021

    Computational Approach Reveals Pronociceptive Potential of Cannabidiol in Osteoarthritis: Role of Transient Receptor Potential Channels

  243. 2021

    COVID-19 and Cannabis: Playing Saint or Devil?

  244. 2021

    Dysregulation of endocannabinoid concentrations in human subcutaneous adipose tissue in obesity and modulation by omega-3 polyunsaturated fatty acids

    FavorávelEstudo LaboratorialInflamaçãoObesidadeSíndrome MetabólicaAnandamida (AEA)
  245. 2021

    Early-life stress induces emotional and molecular alterations in female mice that are partially reversed by cannabidiol

    FavorávelEstudo em AnimaisInflamaçãoAnsiedadeDepressão+4
  246. 2021

    Effect of Ultra-Micronized-Palmitoylethanolamide and Acetyl-l-Carnitine on Experimental Model of Inflammatory Pain

    FavorávelEstudo em AnimaisDorInflamaçãoDor — CrônicaPalmitoiletanolamida (PEA)+3
  247. 2021

    Endocannabinoid and dopaminergic system: the pas de deux underlying human motivation and behaviors

  248. 2021

    Endocannabinoid System as a Promising Therapeutic Target in Inflammatory Bowel Disease - A Systematic Review

  249. 2021

    Endocannabinoid System as Therapeutic Target of PTSD: A Systematic Review

  250. 2021

    Endocannabinoid System in Pregnancy Maintenance and Labor: A Mini-Review

    InconclusivoMetanáliseGestação
  251. 2021

    Endocannabinoid system: Role in blood cell development, neuroimmune interactions and associated disorders

    DesfavorávelMetanáliseDistúrbios de Coagulação
  252. 2021

    Endocannabinoid-mediated neuromodulation in the main olfactory bulb at the interface of environmental stimuli and central neural processing

    FavorávelMetanáliseDoença de AlzheimerDoença de Parkinson
  253. 2021

    Endocannabinoid-serotonin systems interaction in health and disease

    FavorávelMetanáliseAnsiedadeDepressãoEpilepsia+1
  254. 2021

    Endocannabinoids and cortical plasticity: CB1R as a possible regulator of the excitation/inhibition balance in health and disease

    FavorávelMetanálisePsicoseEsquizofrenia
  255. 2021

    Endocannabinoids Attenuate the Virulence of Certain Enteropathogenic Bacteria

  256. 2021

    Endogenous antagonists of N-methyl-d-aspartate receptor in schizophrenia

    InconclusivoMetanálisePsicoseEsquizofrenia
  257. 2021

    Experimental therapies in Irritable Bowel Syndrome

  258. 2021

    From the Clinic to the Laboratory, and Back Again: Investigations on Cannabinoids and Endocannabinoid System Modulators for Treating Schizophrenia

  259. 2021

    Genetic Variants of Fatty Acid Amide Hydrolase Modulate Acute Inflammatory Responses to Colitis in Adult Male Mice

  260. 2021

    Gut barrier and microbiota changes with glycine and branched-chain amino acid supplementation in chronic haemodialysis patients

    DesfavorávelEnsaio Clínico Duplo-CegoInflamaçãoInsuficiência RenalAnandamida (AEA)2-Araquidonoilglicerol (2-AG)+3
  261. 2021

    High and Mighty? Cannabinoids and the microbiome in pain

    FavorávelMetanáliseDorInflamaçãoDor — CrônicaMicrobioma+1
  262. 2021

    High levels of eicosanoids and docosanoids in the lungs of intubated COVID-19 patients

  263. 2021

    Improved cyclobutyl nabilone analogs as potent CB1 receptor agonists

    FavorávelEstudo em AnimaisTHC FarmacêuticoCanabinoides Sintéticos AM-x
  264. 2021

    Interactions between lysophosphatidylinositol receptor GPR55 and sphingosine-1-phosphate receptor S1P5 in live cells

    FavorávelEstudo LaboratorialCâncerCâncer — CólonLisofosfatidilinositol (LPI)
  265. 2021

    Is there a rational basis for cannabinoids research and development in ocular pain therapy? A systematic review of preclinical evidence

  266. 2021

    Letter to the Editor: Ordering the Chaos in Cannabinoid-Related Research: Is it Time for a Task Force on Taxonomy?

    FavorávelMetanálise
  267. 2021

    Lifestyle Interventions Improving Cannabinoid Tone During COVID-19 Lockdowns May Enhance Compliance With Preventive Regulations and Decrease Psychophysical Health Complications

  268. 2021

    Linking the Endocannabinoidome with Specific Metabolic Parameters in an Overweight and Insulin-Resistant Population: From Multivariate Exploratory Analysis to Univariate Analysis and Construction of Predictive Models

  269. 2021

    Metabolic Consequences of Gestational Cannabinoid Exposure

  270. 2021

    Myrcene—What Are the Potential Health Benefits of This Flavouring and Aroma Agent?

    FavorávelMetanáliseDorCâncerInflamação+10
  271. 2021

    New Insights in the Involvement of the Endocannabinoid System and Natural Cannabinoids in Nicotine Dependence

  272. 2021

    Novel Knowledge-Based Transcriptomic Profiling of Lipid Lysophosphatidylinositol-Induced Endothelial Cell Activation

  273. 2021

    Palmitoylethanolamide and Its Biobehavioral Correlates in Autism Spectrum Disorder: A Systematic Review of Human and Animal Evidence

  274. 2021

    Peptide targeting of lysophosphatidylinositol-sensing GPR55 for osteoclastogenesis tuning

    FavorávelEstudo LaboratorialCâncerInflamaçãoCâncer — MetastáticoLisofosfatidilinositol (LPI)+2
  275. 2021

    Pharmacologic Antagonization of Cannabinoid Receptor 1 Improves Cholestasis in Abcb4-/- Mice

    FavorávelEstudo em AnimaisFibroseHepatiteInsuficiência HepáticaCanabinoides Sintéticos SR-x+1
  276. 2021

    Phytocannabinoids and schizophrenia: Focus on adolescence as a critical window of enhanced vulnerability and opportunity for treatment

    InconclusivoMetanálisePsicoseEsquizofrenia
  277. 2021

    Phytocannabinoids—A Green Approach toward Non-Alcoholic Fatty Liver Disease Treatment

  278. 2021

    Polypharmacological Approaches for CNS Diseases: Focus on Endocannabinoid Degradation Inhibition

  279. 2021

    Potent T cell-mediated anti-inflammatory role of the selective CB2 agonist lenabasum in multiple sclerosis

  280. 2021

    Progress on the application of positron emission tomography imaging of cannabinoid type 1 receptor in neuropsychiatric diseases

  281. 2021

    Pros and Cons of the Cannabinoid System in Cancer: Focus on Hematological Malignancies

    FavorávelMetanáliseCâncerCâncer — LeucemiaCâncer — Linfoma+1
  282. 2021

    Psychological and endocannabinoid responses to aerobic exercise in substance use disorder patients

  283. 2021

    Quality of Life and a Surveillant Endocannabinoid System

    FavorávelMetanáliseDorInflamaçãoDor — CrônicaMedicina Mente-Corpo+2
  284. 2021

    Role of cannabinoids in alcohol-induced neuroinflammation

    FavorávelMetanáliseDependência QuímicaInflamaçãoDependência — Álcool
  285. 2021

    Role of PI3K/Akt axis in mitigating hippocampal ischemia-reperfusion injury via CB1 receptor stimulation by paracetamol and FAAH inhibitor in rat

    FavorávelEstudo em AnimaisAVCCOVID-19Anandamida (AEA)Canabinoides Sintéticos AM-x
  286. 2021

    Safety and efficacy of lenabasum in a phase 2 randomized, placebo-controlled trial in adults with cystic fibrosis

    FavorávelEnsaio Clínico Duplo-CegoInflamação
  287. 2021

    Spontaneous and Naloxone-Precipitated Withdrawal Behaviors From Chronic Opiates are Accompanied by Changes in N-Oleoylglycine and N-Oleoylalanine Levels in the Brain and Ameliorated by Treatment With These Mediators

    FavorávelEstudo em Animais
  288. 2021

    Structural correlates of sensorimotor dysfunction in heavy cannabis users

  289. 2021

    Systematic review of the impact of cannabinoids on neurobehavioral outcomes in preclinical models of traumatic and nontraumatic spinal cord injury

  290. 2021

    Targeting the CB 2 receptor and other endocannabinoid elements to delay disease progression in amyotrophic lateral sclerosis

  291. 2021

    Targeting the endocannabinoid system with microbial interventions to improve gut integrity

  292. 2021

    THC Reduces Ki67-Immunoreactive Cells Derived from Human Primary Glioblastoma in a GPR55-Dependent Manner

    FavorávelEstudo LaboratorialCâncerCâncer — CérebroAnandamida (AEA)
  293. 2021

    The CB 1 Receptor Differentially Regulates IFN-γ Production In Vitro and in Experimental Autoimmune Encephalomyelitis

    FavorávelEstudo LaboratorialInflamaçãoEncefalite e Mielite
  294. 2021

    The Current and Potential Application of Medicinal Cannabis Products in Dentistry

    FavorávelMetanáliseDorCâncerInflamaçãoAnandamida (AEA)THC Farmacêutico+26
  295. 2021

    The Effect of CB1 Antagonism on Hepatic Oxidative/Nitrosative Stress and Inflammation in Nonalcoholic Fatty Liver Disease

    FavorávelMetanáliseInflamaçãoEstresse OxidativoEsteatose Hepática
  296. 2021

    The endocannabinoid system in the amygdala and modulation of fear

    FavorávelMetanáliseAnsiedadeDisfunção CognitivaTranstornos de Comportamento+1
  297. 2021

    The gut microbiome, endocannabinoids and metabolic disorders

    FavorávelMetanáliseObesidadeDiabetesSíndrome MetabólicaMicrobioma
  298. 2021

    The use of drug based on technologically processed antibodies to endocannabinoid receptor type 1 in the treatment of obesity in adults: results of a multicenter double blind placebo controlled randomized clinical trial

    FavorávelEnsaio Clínico Duplo-CegoObesidade
  299. 2021

    Therapeutic and Cosmetic Uses of Cannabis: Cannabinoids for Acne Treatment and Skin -Rejuvenation

    FavorávelMetanáliseAcneCanabinoide Sintético (não especificado)
  300. 2021

    Transcriptomic Profiling in Mice With CB1 receptor Deletion in Primary Sensory Neurons Suggests New Analgesic Targets for Neuropathic Pain

    FavorávelEstudo em AnimaisDorInflamaçãoDor — CrônicaCanabinoides Sintéticos AM-x+2
  301. 2018

    CB1 receptors in the paraventricular nucleus of the hypothalamus modulate the release of 5-HT and GABA to stimulate food intake in rats

    FavorávelEstudo em Animais
  302. 2018

    Systemic sclerosis phase III clinical trials: Hope on the horizon?

    FavorávelMetanáliseInflamação
  303. 2016

    α-Pinene, linalool, and 1-octanol contribute to the topical anti-inflammatory and analgesic activities of frankincense by inhibiting COX-2

    FavorávelEstudo em AnimaisDorInflamação
  304. 2015

    Endocannabinoid Regulation of Neuroendocrine Systems.

    FavorávelMetanálise
  305. 2012

    Neuronal populations mediating the effects of endocannabinoids on stress and emotionality.

    FavorávelMetanálise
  306. 2008

    Role of the endocannabinoid system in regulation of the hypothalamic-pituitary-adrenocortical axis.

    FavorávelMetanálise

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Perguntas frequentes

Quantos estudos sobre endocanabinoide (não especificado) estão indexados no acervo?
São 570 estudos, publicados entre 1996 e 2024. O acervo inteiro tem 7.640 registros.
Que tipos de estudo predominam?
Metanálise: 317 · Estudo em Animais: 116 · Estudo Laboratorial: 60 · Ensaio Clínico: 46 · Ensaio Clínico Duplo-Cego: 29 · Metanálise Clínica: 2. A classificação segue o desenho declarado na fonte.
O que significa a classificação de resultado?
É uma leitura automatizada da conclusão de cada estudo, em três direções — favorável, inconclusivo e desfavorável. Aqui são 453 favoráveis, 82 inconclusivos e 35 desfavoráveis. Serve para navegar o acervo, não para concluir nada clinicamente: a conclusão válida é a do artigo original.

Como citar esta página

ABNT

CANNABIS INDICA. Endocanabinoide (não especificado) — estudos científicos sobre cannabis. 2026. Disponível em: https://cannabisindica.com.br/canabinoide/endocanabinoide-nao-especificado/. Acesso em: 13 set. 2026.

APA

Cannabis Indica. (2026). Endocanabinoide (não especificado) — estudos científicos sobre cannabis. https://cannabisindica.com.br/canabinoide/endocanabinoide-nao-especificado/

Esta página é um índice de acesso. Ao usar um estudo como evidência, cite o artigo original — o link de cada registro leva à fonte.