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Estudos 2.001 a 2.100 de 7.640, ordenados do mais recente ao mais antigo — nesta página, publicações de 2021. Para buscar por termo ou combinar filtros, use o acervo com busca.

2021
CB 1 allosteric modulators and their therapeutic potential in CNS disorders
FavorávelMetanáliseCanabinoide Sintético (não especificado)
2021
CB1 Receptor Signaling Modulates Amygdalar Plasticity during Context-Cocaine Memory Reconsolidation to Promote Subsequent Cocaine Seeking
FavorávelEstudo em AnimaisDependência Química Dependência — Cocaína Canabinoides Sintéticos AM-x
2021
CB1R and iNOS are distinct players promoting pulmonary fibrosis in Hermansky–Pudlak syndrome
FavorávelEstudo LaboratorialInflamação Estresse Oxidativo Fibrose Anandamida (AEA)Endocanabinoide (não especificado)+3
2021
CB2 agonism controls pain and subchondral bone degeneration induced by mono-iodoacetate: Implications GPCR functional bias and tolerance development
FavorávelEstudo em AnimaisArtrite Artrite — Osteoartrite Canabinoide Sintético (não especificado)Canabinoides Sintéticos JWH-x
2021
CB2 cannabinoid receptor agonist selectively inhibits the mechanosensitivity of mucosal afferents in the guinea pig bladder
FavorávelEstudo LaboratorialDor Inflamação Cistite Anandamida (AEA)Endocanabinoide (não especificado)
2021
CBD Alleviates Liver Injuries in Alcoholics With High-Fat High-Cholesterol Diet Through Regulating NLRP3 Inflammasome–Pyroptosis Pathway
FavorávelEstudo em AnimaisInflamação Estresse Oxidativo Dependência — Álcool+2
2021
CBD Promotes Oral Ulcer Healing via Inhibiting CMPK2-Mediated Inflammasome
FavorávelEstudo em AnimaisInflamação Cicatrização
2021
CBD-enriched cannabis for autism spectrum disorder: an experience of a single center in Turkey and reviews of the literature
FavorávelEnsaio ClínicoAutismo
2021
CBG, CBD, Δ9-THC, CBN, CBGA, CBDA and Δ9-THCA as antioxidant agents and their intervention abilities in antioxidant action
FavorávelEstudo LaboratorialEstresse Oxidativo Canabigerol (CBG)Canabinol (CBN)+3
2021
Cellular distribution of cannabinoid-related receptors TRPV1, PPAR-gamma, GPR55 and GPR3 in the equine cervical dorsal root ganglia
FavorávelEstudo em AnimaisAplicações Veterinárias
2021
Change in Refractive Error Associated With the Use of Cannabidiol Oil
FavorávelMetanáliseEfeitos Adversos da Cannabis Estresse Oxidativo Diabetes+2
2021
Changes in Hepatic Phospholipid Metabolism in Rats under UV Irradiation and Topically Treated with Cannabidiol
FavorávelEstudo em AnimaisEstresse Oxidativo Insuficiência Hepática Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+1
2021
Changes in Phospholipid/Ceramide Profiles and Eicosanoid Levels in the Plasma of Rats Irradiated with UV Rays and Treated Topically with Cannabidiol
FavorávelEstudo em AnimaisCâncer Inflamação Estresse Oxidativo+1
2021
Characterization of cannabis use by patients with myotonic dystrophy type 1: A pilot study
InconclusivoMetanáliseDistrofia Muscular e Distúrbios Miotônicos
2021
Characterization of chemotype-dependent terpenoids profile in cannabis by headspace gas-chromatography coupled to time-of-flight mass spectrometry
FavorávelEstudo Laboratorial
2021
Characterization of the peripheral FAAH inhibitor, URB937, in animal models of acute and chronic migraine
FavorávelEstudo em AnimaisEnxaqueca Anandamida (AEA)Hidrolase de Amidas de Ácidos Graxos (FAAH)
2021
Chemical and Bioinformatics Analyses of the Anti-Leishmanial and Anti-Oxidant Activities of Hemp Essential Oil
FavorávelEstudo em AnimaisEstresse Oxidativo Leishmaniose
2021
Chemical Composition, Antibacterial, and Anti-Inflammatory Activities of Essential Oils from Flower, Leaf, and Stem of Rhynchanthus beesianus
FavorávelEstudo LaboratorialInflamação Infecções Bacterianas
2021
Chemical Emissions From Heated Vitamin E Acetate—Insights to Respiratory Risks From Electronic Cigarette Liquid Oil Diluents Used in the Aerosolization of Δ9-THC-Containing Products
DesfavorávelEstudo LaboratorialEfeitos Adversos da Cannabis Lesão Pulmonar por Vaping (EVALI)Canabinoide Sintético (não especificado)
2021
Chemopreventive potential of linalool in targeting lung cancer biomarkers: An in silico & in vitro investigation
FavorávelEstudo LaboratorialCâncer Câncer — Pulmão
2021
Chronic administration of synthetic cannabidiol induces antidepressant effects involving modulation of serotonin and noradrenaline levels in the hippocampus
FavorávelEstudo em AnimaisDepressão
2021
Chronic cannabidiol (CBD) administration induces anticonvulsant and antiepileptogenic effects in a genetic model of epilepsy
FavorávelEstudo em AnimaisEpilepsia
2021
Chronic cannabidiol treatment reduces the carbachol-induced coronary constriction and left ventricular cardiomyocyte width of the isolated hypertensive rat heart
InconclusivoEstudo em AnimaisDoenças Cardiovasculares (DCV)Hipertensão Arterial
2021
Chronic cannabinoid exposure produces tolerance to the dopamine releasing effects of WIN 55,212-2 and heroin in adult male rats
InconclusivoEstudo em AnimaisDependência — Opioides Canabinoides Sintéticos WIN-x
2021
Chronic Marijuana Consumption Leading to High-Grade Atrioventricular Block in a Young Male
DesfavorávelMetanáliseEfeitos Adversos da Cannabis Doenças Cardiovasculares (DCV)Arritmias Cardíacas
2021
Chronic Pain in Dogs and Cats: Is There Place for Dietary Intervention with Micro-Palmitoylethanolamide?
FavorávelMetanáliseAplicações Veterinárias Palmitoiletanolamida (PEA)
2021
Chronic Treatment with Cannabidiolic Acid (CBDA) Reduces Thermal Pain Sensitivity in Male Mice and Rescues the Hyperalgesia in a Mouse Model of Rett Syndrome
FavorávelEstudo em AnimaisDor Ansiedade Dor — Crônica Ácido Canabidiólico (CBD-a)+5
2021
Circulating endocannabinoids and prospective risk for depression in trauma-injury survivors
InconclusivoMetanáliseDepressão Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+2
2021
Circulating Endocannabinoids as Diagnostic Markers of Canine Chronic Enteropathies: A Pilot Study
InconclusivoEstudo em AnimaisAplicações Veterinárias Anandamida (AEA)2-Araquidonoilglicerol (2-AG)
2021
Circulating fatty acids and endocannabinoidome-related mediator profiles associated to human longevity
FavorávelMetanáliseLongevidade Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+3
2021
Citalopram and Cannabidiol: In Vitro and In Vivo Evidence of Pharmacokinetic Interactions Relevant to the Treatment of Anxiety Disorders in Young People
DesfavorávelEstudo LaboratorialAnsiedade Depressão
2021
Clinical outcome data of first cohort of chronic pain patients treated with cannabis-based sublingual oils in the United Kingdom - analysis from the UK Medical Cannabis Registry
FavorávelMetanáliseDor Dor — Crônica Insônia e Distúrbios do Sono
2021
Clinical symptoms and blood concentration of new psychoactive substances (NPS) in intoxicated and hospitalized patients in the Budapest region of Hungary (2018-19)
DesfavorávelMetanáliseEfeitos Adversos da Cannabis Canabinoides Sintéticos 5F-x
2021
Clinical Trials of Cannabidiol for Substance Use Disorders: Outcome Measures, Surrogate Endpoints, and Biomarkers
FavorávelMetanálise ClínicaDependência — Cannabis Dependência — Opioides Dependência — Álcool+2
2021
Co-administration of cannabidiol and ketamine induces antidepressant-like effects devoid of hyperlocomotor side-effects
FavorávelEstudo em AnimaisDepressão
2021
Co-exposure of cocaine and cannabinoids and its association with select biological, behavioural and health outcomes: A systematic scoping review of multi-disciplinary studies
InconclusivoMetanáliseDependência Química Efeitos Adversos da Cannabis Dependência — Cocaína
2021
Cognition and Cortical Thickness in Heavy Cannabis Users
DesfavorávelEnsaio ClínicoEfeitos Adversos da Cannabis Dependência — Cannabis Disfunção Cognitiva
2021
Cognitive and behavioral effects of cannabidiol in patients with treatment-resistant epilepsy
FavorávelEnsaio ClínicoEpilepsia
2021
Cognitive performance and lifetime cannabis use in patients with first-episode schizophrenia spectrum disorder
FavorávelEnsaio ClínicoEfeitos Adversos da Cannabis Psicose Esquizofrenia
2021
Combination therapy with cannabidiol and chemotherapeutics in canine urothelial carcinoma cells
FavorávelEstudo LaboratorialAplicações Veterinárias
2021
Combined Antiseizure Efficacy of Cannabidiol and Clonazepam in a Conditional Mouse Model of Dravet Syndrome
FavorávelEstudo em AnimaisEpilepsia Epilepsia — Síndrome de Dravet
2021
Combined effect of alcohol and cannabis on simulated driving
DesfavorávelEnsaio Clínico Duplo-CegoEfeitos Adversos da Cannabis
2021
Combined pharmacotherapy and evidence-based psychosocial Cannabis treatment for youth and selection of cannabis-using friends
FavorávelEnsaio Clínico Duplo-CegoDependência Química Dependência — Cannabis
2021
Community nurses' support for patients with fibromyalgia who use cannabis to manage pain
FavorávelMetanáliseFibromialgia
2021
Comorbid anxiety-like behavior in a rat model of colitis is mediated by an upregulation of corticolimbic fatty acid amide hydrolase
FavorávelEstudo em AnimaisInflamação Ansiedade Depressão Anandamida (AEA)Endocanabinoide (não especificado)+8
2021
Comorbid Cannabis Use Disorder with Major Depression and Generalized Anxiety Disorder: A Systematic Review with Meta-analysis of Nationally Representative Epidemiological Surveys
DesfavorávelMetanáliseDependência Química Dependência — Cannabis
2021
Component of Cannabis, Cannabidiol, as a Possible Drug against the Cytotoxicity of Aβ(31–35) and Aβ(25–35) Peptides: An Investigation by Molecular Dynamics and Well-Tempered Metadynamics Simulations
FavorávelEstudo LaboratorialDoença de Alzheimer
2021
Components of the Endocannabinoid System and Effects of Cannabinoids Against Bone Diseases: A Mini-Review
FavorávelMetanáliseCâncer Artrite Artrite — Osteoartrite+3
2021
Components of the Endogenous Cannabinoid System as Potential Biomarkers for Interstitial Cystitis/Bladder Pain Syndrome
FavorávelMetanáliseDor Dor — Crônica Cistite Endocanabinoide (não especificado)
2021
Compound Danshen Dripping Pill ameliorates post ischemic myocardial inflammation through synergistically regulating MAPK, PI3K/AKT and PPAR signaling pathways
FavorávelEstudo em AnimaisInflamação Doenças Cardiovasculares (DCV)
2021
Computational Approach Reveals Pronociceptive Potential of Cannabidiol in Osteoarthritis: Role of Transient Receptor Potential Channels
FavorávelEstudo em AnimaisInflamação Artrite Anandamida (AEA)Endocanabinoide (não especificado)+1
2021
Computational insight into the protective mechanism of Allium iranicum Wendelbo. Alliaceae in a mouse model of Staphylococcosis: focus on dietary phytocannabinoid trans-caryophyllene
FavorávelEstudo em AnimaisInfecção por Estafilococos Outros Compostos Relacionados
2021
Computer- vs. nurse practitioner-delivered brief intervention for adolescent marijuana, alcohol, and sex risk behaviors in school-based health centers
InconclusivoEnsaio ClínicoDependência Química Efeitos Adversos da Cannabis Dependência — Cannabis+1
2021
Confirming Savoring's Link to Fewer Cannabis Problems
FavorávelMetanáliseEfeitos Adversos da Cannabis Dependência — Cannabis Medicina Mente-Corpo
2021
Consensus-based recommendations for titrating cannabinoids and tapering opioids for chronic pain control
FavorávelMetanáliseDor Dor — Crônica Dependência — Opioides
2021
Consumer Experiences with Delta-8-THC: Medical Use, Pharmaceutical Substitution, and Comparisons with Delta-9-THC
FavorávelMetanáliseDor Ansiedade Dor — Crônica Delta-8-THC+2
2021
Contingency management for alcohol use disorder reduces cannabis use among American Indian and Alaska Native adults
FavorávelEnsaio ClínicoDependência Química Dependência — Cannabis Dependência — Álcool+3
2021
Contribution of Fatty Acid Amide Hydrolase to Alcohol Use Disorder: A Systematic Review
InconclusivoMetanáliseDependência Química Dependência — Álcool Anandamida (AEA)Hidrolase de Amidas de Ácidos Graxos (FAAH)
2021
Contribution of the Adenosine 2A Receptor to Behavioral Effects of Tetrahydrocannabinol, Cannabidiol and PECS-101
DesfavorávelEstudo em AnimaisDor Inflamação Efeitos Adversos da Cannabis+6
2021
Correlates of High HIV Viral Load and Antiretroviral Therapy Adherence Among Viremic Youth in the United States Enrolled in an Adherence Improvement Intervention
DesfavorávelEnsaio ClínicoDependência Química Dependência — Cannabis Depressão+1
2021
Cost-effectiveness of adding Sativex® spray to spasticity care in Belgium: using bootstrapping instead of Monte Carlo simulation for probabilistic sensitivity analyses
FavorávelMetanáliseEsclerose Múltipla THC:CBD Farmacêutico
2021
Cost-Effectiveness of Medicinal Cannabis for Management of Refractory Symptoms Associated With Chronic Conditions: A Systematic Review of Economic Evaluations
FavorávelMetanáliseDor Dor — Crônica Epilepsia THC Farmacêutico THC:CBD Farmacêutico+8
2021
Could Cannabidiol Be a Treatment for Coronavirus Disease-19-Related Anxiety Disorders?
FavorávelMetanáliseAnsiedade Depressão Insônia e Distúrbios do Sono+2
2021
COVID-19 and Cannabis: Playing Saint or Devil?
FavorávelMetanáliseInflamação Doenças Cardiovasculares (DCV)Hipertensão Arterial Endocanabinoide (não especificado)+1
2021
Craving management: Exploring factors that influence momentary craving-related risk of cannabis use among young adults
InconclusivoMetanáliseDependência Química Dependência — Cannabis Medicina Mente-Corpo
2021
Creatine kinase levels in psychotic patients who use cannabinoids
InconclusivoMetanálisePsicose
2021
Cross-sectional and longitudinal evaluation of cannabidiol (CBD) product use and health among people with epilepsy
FavorávelMetanáliseEpilepsia
2021
Crosstalk between the transcriptional regulation of dopamine D2 and cannabinoid CB1 receptors in schizophrenia: Analyses in patients and in perinatal Δ9-tetrahydrocannabinol-exposed rats
FavorávelEstudo em AnimaisPsicose Esquizofrenia Tetraidrocanabinol (THC)
2021
Curcumae Longae Rhizoma and Saussureae Radix Inhibit Nitric Oxide Production and Cannabinoid Receptor 2 Down-regulation
FavorávelEstudo LaboratorialInflamação
2021
Current controversies in medical cannabis: Recent developments in human clinical applications and potential therapeutics
InconclusivoMetanáliseAnsiedade Epilepsia Esclerose Múltipla+1
2021
Current review of hemp-based medicines in dogs
FavorávelMetanáliseEpilepsia Artrite Aplicações Veterinárias+1
2021
Cytochrome P450-Catalyzed Metabolism of Cannabidiol to the Active Metabolite 7-Hydroxy-Cannabidiol
DesfavorávelEstudo LaboratorialEpilepsia Epilepsia — Síndrome de Dravet Epilepsia — Lennox-Gastaut CBD Farmacêutico+2
2021
D-Limonene Is a Potential Monoterpene to Inhibit PI3K/Akt/IKK-α/NF-κB p65 Signaling Pathway in Coronavirus Disease 2019 Pulmonary Fibrosis
FavorávelEstudo em AnimaisCOVID-19 Fibrose Fibrose — Pulmonar
2021
D-limonene: A multifunctional compound with potent therapeutic effects
FavorávelMetanáliseCâncer Inflamação Doenças Cardiovasculares (DCV)+2
2021
Daily Cannabis Use is Associated With Lower CNS Inflammation in People With HIV
FavorávelMetanáliseInflamação HIV/AIDS
2021
Daily, but not occasional, cannabis use is selectively associated with more impulsive delay discounting and hyperactive ADHD symptoms in binge-drinking young adults
InconclusivoEnsaio ClínicoDisfunção Cognitiva Dependência — Álcool TDA e TDAH
2021
Day-level shifts in social contexts during youth cannabis use treatment
FavorávelEnsaio Clínico Duplo-CegoDependência Química Dependência — Cannabis
2021
Death of a young woman with cyclic vomiting: a case report
DesfavorávelMetanáliseEfeitos Adversos da Cannabis Doenças Cardiovasculares (DCV)Náusea e Vômito+2
2021
Decision Making and Impulsivity in Young Adult Cannabis Users
DesfavorávelMetanáliseEfeitos Adversos da Cannabis
2021
Delivering therapeutic cannabinoids via skin: Current state and future perspectives
FavorávelMetanáliseTHC Farmacêutico THC:CBD Farmacêutico+1
2021
Demographics, Perceptions, and Use of Medical Marijuana among Patients in Florida
FavorávelMetanáliseDor Ansiedade Dor — Crônica
2021
Depressive symptoms and cannabis use in a placebo-controlled trial of N-Acetylcysteine for adult cannabis use disorder
InconclusivoEnsaio ClínicoDependência Química Efeitos Adversos da Cannabis Dependência — Cannabis Tetraidrocanabinol (THC)+1
2021
Design of Negative and Positive Allosteric Modulators of the Cannabinoid CB 2 Receptor Derived from the Natural Product Cannabidiol
FavorávelEstudo LaboratorialDor Inflamação Efeitos Adversos da Cannabis+3
2021
Desistance, Self-treatment, or Substitution: Decisions about Cannabis Use During Pregnancy
InconclusivoMetanáliseEfeitos Adversos da Cannabis Dependência — Cannabis Ansiedade+4
2021
Destabilization of the Alzheimer's amyloid-β protofibrils by THC: A molecular dynamics simulation study
FavorávelEstudo LaboratorialDoença de Alzheimer
2021
Detectability of cannabinoids in the serum samples of cannabis users: Indicators of recent cannabis use? A follow-up study
FavorávelEnsaio ClínicoCanabigerol (CBG)Canabinol (CBN)+8
2021
Determining the magnitude and duration of acute Δ9-tetrahydrocannabinol (Δ9-THC)-induced driving and cognitive impairment: A systematic and meta-analytic review
DesfavorávelMetanálise ClínicaDisfunção Cognitiva
2021
Developing a real-world evidence base for prescribed cannabis in the United Kingdom: preliminary findings from Project Twenty21
FavorávelMetanáliseDor Ansiedade Dor — Crônica+2
2021
Development and Optimization of Supercritical Fluid Extraction Setup Leading to Quantification of 11 Cannabinoids Derived from Medicinal Cannabis
InconclusivoEstudo LaboratorialTetraidrocanabinol (THC)Canabigerol (CBG)+8
2021
Development of central precocious puberty following cannabinoid use for paediatric epilepsy: causal or coincidence?
FavorávelMetanáliseEpilepsia
2021
Developmental cannabidiol exposure increases anxiety and modifies genome-wide brain DNA methylation in adult female mice
InconclusivoEstudo em AnimaisAnsiedade Disfunção Cognitiva Gestação CBD Farmacêutico+1
2021
Different responses of repetitive behaviours in juvenile and young adult mice to Δ 9 -tetrahydrocannabinol and cannabidiol may affect decision making for Tourette syndrome
DesfavorávelEstudo em AnimaisTiques e Síndrome de Tourette
2021
Differential contribution of CB1, CB2, 5-HT1A, and PPAR-γ receptors to cannabidiol effects on ischemia-induced emotional and cognitive impairments
FavorávelEstudo em AnimaisAnsiedade Disfunção Cognitiva AVC
2021
Differential Interactions of Selected Phytocannabinoids with Human CYP2D6 Polymorphisms
InconclusivoEstudo LaboratorialAnandamida (AEA)Tetraidrocanabinol (THC)+4
2021
Differentially expressed genes induced by β-caryophyllene in a rat model of cerebral ischemia-reperfusion injury
FavorávelEstudo em AnimaisDoenças Cardiovasculares (DCV)AVC Lesão de Reperfusão
2021
Disease-Dependent Antiapoptotic Effects of Cannabidiol for Keratinocytes Observed upon UV Irradiation
FavorávelEstudo LaboratorialPsoríase Queimadura Solar
2021
Disentangling the lasting effects of adolescent cannabinoid exposure
DesfavorávelMetanáliseEfeitos Adversos da Cannabis
2021
Disposition of cannabinoids and their metabolites in serum, oral fluid, sweat patch and urine from healthy individuals treated with pharmaceutical preparations of medical cannabis
FavorávelEstudo LaboratorialInsônia e Distúrbios do Sono Perda de Apetite Ácido Canabidiólico (CBD-a)Ácido Tetraidrocanabinólico (THC-a)
2021
Distribution of inhaled volatile β-caryophyllene and dynamic changes of liver metabolites in mice
InconclusivoEstudo em Animais
2021
Does cannabis use in adolescence predict self‐harm or suicide? Results from a Finnish Birth Cohort Study
DesfavorávelMetanáliseEfeitos Adversos da Cannabis Psicose Dependência — Opioides+6