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Estudos 2.101 a 2.200 de 7.640, ordenados do mais recente ao mais antigo — nesta página, publicações de 2021. Para buscar por termo ou combinar filtros, use o acervo com busca.

2021
Dose-Related Inhibition of Capsaicin Responses by Cannabinoids CBG, CBD, THC and their Combination in Cultured Sensory Neurons
FavorávelEstudo LaboratorialDor Dor — Crônica Dor — Aguda Canabigerol (CBG)Canabicromeno (CBC)+1
2021
Down and High: Reflections Regarding Depression and Cannabis
DesfavorávelMetanáliseDependência Química Dependência — Cannabis Depressão
2021
Dravet syndrome
FavorávelMetanáliseEpilepsia Epilepsia — Síndrome de Dravet
2021
Dronabinol inhibits alveolar bone remodeling in tooth movement of rats
DesfavorávelEstudo em AnimaisEfeitos Adversos da Cannabis Fraturas Ósseas Perda Óssea Induzida por Medicamentos THC Farmacêutico
2021
Duration of Neurocognitive Impairment With Medical Cannabis Use: A Scoping Review
FavorávelMetanálise ClínicaDor Efeitos Adversos da Cannabis Disfunção Cognitiva
2021
Dysregulation of endocannabinoid concentrations in human subcutaneous adipose tissue in obesity and modulation by omega-3 polyunsaturated fatty acids
FavorávelEstudo LaboratorialInflamação Obesidade Síndrome Metabólica Anandamida (AEA)Endocanabinoide (não especificado)
2021
E-Cigarette or Vaping Associated Lung Injury: Evolving Threat to Healthy Teens
DesfavorávelMetanáliseEfeitos Adversos da Cannabis Lesão Pulmonar por Vaping (EVALI)
2021
Early life stress and development of the endocannabinoid system: A bidirectional process in programming future coping
InconclusivoMetanáliseGestação Anandamida (AEA)2-Araquidonoilglicerol (2-AG)
2021
Early-life stress induces emotional and molecular alterations in female mice that are partially reversed by cannabidiol
FavorávelEstudo em AnimaisInflamação Ansiedade Depressão Endocanabinoide (não especificado)+4
2021
Early, Chronic, and Acute Cannabis Exposure and Their Relationship With Cognitive and Behavioral Harms
DesfavorávelEnsaio ClínicoEfeitos Adversos da Cannabis Dependência — Cannabis Dependência — Álcool
2021
Effect of acute and subchronic administration of (R)-WIN55,212-2 induced neuroprotection and anti inflammatory actions in rat retina: CB1 and CB2 receptor involvement
FavorávelEstudo em AnimaisDoenças da Retina Excitotoxicidade Canabinoides Sintéticos WIN-x
2021
Effect of Cannabidiol (CBD) on Canine Inflammatory Response: An Ex Vivo Study on LPS Stimulated Whole Blood
FavorávelEstudo LaboratorialAplicações Veterinárias
2021
Effect of Cannabidiol and Δ9-Tetrahydrocannabinol on Driving Performance: A Randomized Clinical Trial
DesfavorávelEnsaio Clínico Duplo-CegoEfeitos Adversos da Cannabis Disfunção Cognitiva
2021
Effect of Cannabidiol on Interictal Epileptiform Activity and Sleep Architecture in Children with Intractable Epilepsy: A Prospective Open-Label Study
FavorávelEnsaio ClínicoEpilepsia Epilepsia — Síndrome de Dravet Epilepsia — Lennox-Gastaut CBD Farmacêutico
2021
Effect of Cannabinoid 2 Receptor Modulation on the Peripheral Immune Response in Central Nervous System Injury-Induced Immunodeficiency Syndrome
FavorávelEstudo em AnimaisAVC Lesões da Medula Espinhal Traumatismo Cranioencefálico Canabinoides Sintéticos AM-x Canabinoides Sintéticos HU-x+1
2021
Effect of cannabis on oxaliplatin-induced peripheral neuropathy among oncology patients: a retrospective analysis
FavorávelEnsaio ClínicoDor Câncer Dor — Neuropatia Periférica+1
2021
Effect of COVID-19 Pandemic on Cannabis Use in Cancer Patients
InconclusivoMetanáliseCâncer COVID-19
2021
Effect of d-limonene and its derivatives on breast cancer in human trials: a scoping review and narrative synthesis
FavorávelMetanálise ClínicaCâncer Câncer — Mama
2021
Effect of Dipeptidyl Peptidase-4 (DPP-4) Inhibition on Biomarkers of Kidney Injury and Vascular Calcification in Diabetic Kidney Disease: A Randomized Controlled Trial
FavorávelEnsaio ClínicoInflamação Diabetes Nefropatia Diabética Proteína Ligadora de Ácidos Graxos (FABP)
2021
Effect of nabiximols on Goal Attainment Scale scores in patients with treatment-resistant multiple sclerosis spasticity
FavorávelMetanáliseEsclerose Múltipla THC:CBD Farmacêutico
2021
Effect of screening, brief intervention and referral to treatment for unhealthy alcohol and other drug use in mental health treatment settings: a randomized controlled trial
FavorávelEnsaio ClínicoDependência Química Dependência — Cannabis Dependência — Álcool+1
2021
Effect of two oral formulations of cannabidiol on responses to emotional stimuli in healthy human volunteers: pharmaceutical vehicle matters
InconclusivoEnsaio Clínico Duplo-CegoAnsiedade Disfunção Cognitiva
2021
Effect of Ultra-Micronized-Palmitoylethanolamide and Acetyl-l-Carnitine on Experimental Model of Inflammatory Pain
FavorávelEstudo em AnimaisDor Inflamação Dor — Crônica Endocanabinoide (não especificado)Palmitoiletanolamida (PEA)+3
2021
Effect of α-pinene and thymoquinone on the differentiation of bone marrow mesenchymal stem cells into neuroprogenitor cells
FavorávelEstudo LaboratorialDoenças Neurodegenerativas
2021
Effect of β-Caryophyllene on insulin resistance in skeletal muscle of high fat diet and fructose-induced type-2 diabetic rats
FavorávelEstudo em AnimaisDiabetes Síndrome Metabólica
2021
Effectiveness of attentional bias modification training as add-on to regular treatment in alcohol and cannabis use disorder: A multicenter randomized control trial
InconclusivoEnsaio ClínicoDependência Química Efeitos Adversos da Cannabis Dependência — Álcool
2021
Effectiveness of complementary therapies for the management of symptom clusters in palliative care in pediatric oncology: a systematic review
FavorávelMetanáliseDor Câncer Ansiedade+2
2021
Effectiveness, safety and tolerability of nabiximols oromucosal spray versus typical oral long-acting opioid analgesics in patients with severe neuropathic back pain: analysis of 6-month real-world data from the German Pain e-Registry
FavorávelMetanáliseDor Dor — Crônica Dor — Neuropatia Periférica THC:CBD Farmacêutico
2021
Effects of a cannabis use disorder text message-delivered treatment on young adult alcohol misuse: Differential effects by gender
InconclusivoEnsaio ClínicoDependência Química Efeitos Adversos da Cannabis Dependência — Cannabis+1
2021
Effects of a Novel GPR55 Antagonist on the Arachidonic Acid Cascade in LPS-Activated Primary Microglial Cells
FavorávelEstudo LaboratorialInflamação Depressão Doença de Alzheimer Canabinoide Sintético (não especificado)
2021
Effects of Acute Drug Administration on Emotion: A Review of Pharmacological MRI Studies
InconclusivoMetanáliseEfeitos Adversos da Cannabis Dependência — Opioides Dependência — Álcool+1
2021
Effects of cannabidiol (CBD) on the inhibition of melanoma cells in vitro
FavorávelEstudo LaboratorialCâncer Câncer — Melanoma
2021
Effects of Cannabidiol and Beta-Caryophyllene Alone or in Combination in a Mouse Model of Permanent Ischemia
FavorávelEstudo em AnimaisAVC
2021
Effects of Cannabidiol Chewing Gum on Perceived Pain and Well-Being of Irritable Bowel Syndrome Patients: A Placebo-Controlled Crossover Exploratory Intervention Study with Symptom-Driven Dosing
InconclusivoEnsaio Clínico Duplo-CegoSíndrome do Intestino Irritável
2021
Effects of cannabidiol in cannabis flower: Implications for harm reduction
FavorávelEnsaio ClínicoEfeitos Adversos da Cannabis
2021
Effects of Cannabidiol on the In Vitro Lymphocyte Pro-Inflammatory Cytokine Production of Senior Horses
FavorávelEstudo LaboratorialAplicações Veterinárias
2021
Effects of Cannabinoid Agonists and Antagonists on Sleep in Laboratory Animals
FavorávelMetanáliseInsônia e Distúrbios do Sono
2021
Effects of Cannabis Consumption on Sleep
InconclusivoMetanáliseInsônia e Distúrbios do Sono
2021
Effects of cannabis on visual function and self-perceived visual quality
DesfavorávelEnsaio ClínicoDor Glaucoma Dor — Ocular+5
2021
Effects of cannabis use on alcohol consumption in a sample of treatment-engaged heavy drinkers in Colorado
FavorávelMetanáliseDependência Química Dependência — Álcool
2021
Effects of daily Δ 9-Tetrahydrocannabinol (THC) alone or combined with cannabidiol (CBD) on cognition-based behavior and activity in adolescent nonhuman primates
InconclusivoEstudo em AnimaisEfeitos Adversos da Cannabis
2021
Effects of repeated adolescent exposure to cannabis smoke on cognitive outcomes in adulthood
DesfavorávelEstudo em AnimaisEfeitos Adversos da Cannabis Ansiedade Disfunção Cognitiva Canabinol (CBN)
2021
Effects of systemic endocannabinoid manipulation on social and exploratory behavior in prairie voles (Microtus ochrogaster)
InconclusivoEstudo em AnimaisAnsiedade Anandamida (AEA)
2021
Effects of tetrahydrocannabinols on human oral cancer cell proliferation, apoptosis, autophagy, oxidative stress, and DNA damage
FavorávelEstudo LaboratorialCâncer Estresse Oxidativo Câncer — Boca Delta-8-THC
2021
Effects of topiramate on the association between affect, cannabis craving, and cannabis use in the daily life of youth during a randomized clinical trial
FavorávelEnsaio Clínico Duplo-CegoDependência Química Dependência — Cannabis
2021
Effects of vapourized THC and voluntary alcohol drinking during adolescence on cognition, reward, and anxiety-like behaviours in rats
InconclusivoEstudo em AnimaisDependência Química Ansiedade Disfunção Cognitiva+1
2021
Effects on the Post-translational Modification of H3K4Me3, H3K9ac, H3K9Me2, H3K27Me3, and H3K36Me2 Levels in Cerebral Cortex, Hypothalamus and Pons of Rats after a Systemic Administration of Cannabidiol: A Preliminary Study
InconclusivoEstudo LaboratorialInsônia e Distúrbios do Sono
2021
Efficacy and Safety of Cannabidiol Plus Standard Care vs Standard Care Alone for the Treatment of Emotional Exhaustion and Burnout Among Frontline Health Care Workers During the COVID-19 Pandemic
FavorávelEnsaio ClínicoAnsiedade Depressão
2021
Efficacy and safety of medical cannabinoids in children: a systematic review and meta-analysis
FavorávelMetanáliseEfeitos Adversos da Cannabis Epilepsia Epilepsia — Síndrome de Dravet THC Farmacêutico THC:CBD Farmacêutico+3
2021
Efficacy and safety of paediatric medicinal cannabis use: A scoping review
DesfavorávelMetanáliseDor Câncer Epilepsia THC Farmacêutico CBD Farmacêutico+7
2021
Efficacy of a fixed combination of palmitoylethanolamide and acetyl-l-carnitine (PEA+ALC FC) in the treatment of neuropathies secondary to rheumatic diseases
FavorávelEnsaio ClínicoDor Inflamação Dor — Crônica Palmitoiletanolamida (PEA)+4
2021
Efficacy of Cannabidiol for Δ-9-Tetrahydrocannabinol-Induced Psychotic Symptoms, Schizophrenia, and Cannabis Use Disorders: A Narrative Review
FavorávelMetanálise ClínicaDependência Química Dependência — Cannabis Psicose+1
2021
Efficacy of cannabinoids against glioblastoma multiforme: A systematic review
FavorávelMetanáliseCâncer Câncer — Neuroblastoma
2021
Efficacy of cannabis-based medications compared to placebo for the treatment of chronic neuropathic pain: a systematic review with meta-analysis
FavorávelMetanálise ClínicaDor Dor — Crônica THC Farmacêutico THC:CBD Farmacêutico+1
2021
Efficacy of combined therapy with fish oil and phytocannabinoids in murine intestinal inflammation
FavorávelEstudo em AnimaisInflamação DII — Doença Inflamatória Intestinal Canabigerol (CBG)
2021
Efficacy of Phytocannabinoids in Epilepsy Treatment: Novel Approaches and Recent Advances
InconclusivoMetanáliseEpilepsia Canabigerol (CBG)Canabidivarina (CBDV)
2021
Efficacy of topical capsaicin for cannabinoid hyperemesis syndrome in a pediatric and adult emergency department
FavorávelEnsaio ClínicoDor Náusea e Vômito Dor — Aguda Capsaicina (CAPS)+1
2021
Efficacy of topical capsaicin for the treatment of cannabinoid hyperemesis syndrome: A retrospective cohort study
InconclusivoMetanáliseSíndrome da Hiperêmese Canabinoide Capsaicina (CAPS)
2021
Efficacy of Δ9 -Tetrahydrocannabinol (THC) Alone or in Combination With a 1:1 Ratio of Cannabidiol (CBD) in Reversing the Spatial Learning Deficits in Old Mice
DesfavorávelEstudo em AnimaisDisfunção Cognitiva THC:CBD Farmacêutico
2021
eHealth Interventions to Treat Substance Use in Pregnancy: A Systematic Review and Meta-Analysis
FavorávelMetanálise ClínicaDependência Química Efeitos Adversos da Cannabis Dependência — Cannabis+3
2021
Electrochemical sensing: A prognostic tool in the fight against COVID-19
FavorávelMetanáliseInflamação COVID-19
2021
Emerging potential of cannabidiol in reversing proteinopathies
FavorávelMetanáliseEsclerose Múltipla Doença de Alzheimer Doença de Parkinson+2
2021
Emerging role of cannabinoids and synthetic cannabinoid receptor 1/cannabinoid receptor 2 receptor agonists in cancer treatment and chemotherapy-associated cancer management
FavorávelMetanáliseDor Câncer Ansiedade+5
2021
Emotion regulation in emerging adults with major depressive disorder and frequent cannabis use
InconclusivoEnsaio ClínicoDependência — Cannabis Depressão
2021
Endocannabinoid Anandamide Attenuates Acute Respiratory Distress Syndrome through Modulation of Microbiome in the Gut-Lung Axis
FavorávelEstudo em AnimaisCOVID-19 Desequilíbrio do Microbioma Estresse Anandamida (AEA)Hidrolase de Amidas de Ácidos Graxos (FAAH)+2
2021
Endocannabinoid and dopaminergic system: the pas de deux underlying human motivation and behaviors
InconclusivoMetanáliseObesidade Síndrome Metabólica Endocanabinoide (não especificado)Canabinoide Sintético (não especificado)
2021
Endocannabinoid Gene × Gene Interaction Association to Alcohol Use Disorder in Two Adolescent Cohorts
InconclusivoMetanáliseDependência Química Dependência — Álcool Monoacilglicerol Lipase (MAGL)Outros Compostos Relacionados
2021
Endocannabinoid markers in autism spectrum disorder: A scoping review of human studies
InconclusivoMetanálise ClínicaAutismo Anandamida (AEA)2-Araquidonoilglicerol (2-AG)
2021
Endocannabinoid Metabolism and Traumatic Brain Injury
FavorávelMetanáliseDoença de Alzheimer Traumatismo Cranioencefálico 2-Araquidonoilglicerol (2-AG)Monoacilglicerol Lipase (MAGL)
2021
Endocannabinoid Modulation Using Monoacylglycerol Lipase Inhibition in Tourette Syndrome: A Phase 1 Randomized, Placebo-Controlled Study
FavorávelEnsaio Clínico Duplo-CegoAnsiedade Depressão Doenças Neurodegenerativas Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+4
2021
Endocannabinoid System and Its Regulation by Polyunsaturated Fatty Acids and Full Spectrum Hemp Oils
FavorávelMetanáliseSíndrome Metabólica
2021
Endocannabinoid System as a Promising Therapeutic Target in Inflammatory Bowel Disease - A Systematic Review
FavorávelMetanáliseInflamação Estresse Oxidativo DII — Doença Inflamatória Intestinal Anandamida (AEA)Endocanabinoide (não especificado)+11
2021
Endocannabinoid System as Therapeutic Target of PTSD: A Systematic Review
FavorávelMetanáliseTEPT Endocanabinoide (não especificado)Hidrolase de Amidas de Ácidos Graxos (FAAH)+1
2021
Endocannabinoid System in Pregnancy Maintenance and Labor: A Mini-Review
InconclusivoMetanáliseGestação Endocanabinoide (não especificado)
2021
Endocannabinoid system mediates the association between gut-microbial diversity and anhedonia/amotivation in a general population cohort
FavorávelMetanáliseDepressão Psicose Desequilíbrio do Microbioma Palmitoiletanolamida (PEA)Microbioma
2021
Endocannabinoid system: Role in blood cell development, neuroimmune interactions and associated disorders
DesfavorávelMetanáliseDistúrbios de Coagulação Endocanabinoide (não especificado)
2021
Endocannabinoid-mediated neuromodulation in the main olfactory bulb at the interface of environmental stimuli and central neural processing
FavorávelMetanáliseDoença de Alzheimer Doença de Parkinson Endocanabinoide (não especificado)
2021
Endocannabinoid-mediated synaptic plasticity and substance use disorders
FavorávelMetanáliseDependência — Cannabis Dependência — Opioides Dependência — Álcool Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+2
2021
Endocannabinoid-serotonin systems interaction in health and disease
FavorávelMetanáliseAnsiedade Depressão Epilepsia Endocanabinoide (não especificado)+1
2021
Endocannabinoids and cortical plasticity: CB1R as a possible regulator of the excitation/inhibition balance in health and disease
FavorávelMetanálisePsicose Esquizofrenia Endocanabinoide (não especificado)
2021
Endocannabinoids and Heart Rate Variability Alterations after Exposure to Prolonged Intensive Physical Exercise of the Hellenic Navy SEALs
FavorávelEnsaio ClínicoEstresse Oxidativo Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+3
2021
Endocannabinoids Attenuate the Virulence of Certain Enteropathogenic Bacteria
FavorávelMetanáliseDII — Doença Inflamatória Intestinal Infecções Bacterianas Endocanabinoide (não especificado)2-Araquidonoilglicerol (2-AG)
2021
Endocannabinoids increase human adipose stem cell differentiation and growth factor secretion in vitro
FavorávelEstudo LaboratorialAnandamida (AEA)2-Araquidonoilglicerol (2-AG)
2021
Endocannabinoids, cannabinoids and the regulation of anxiety
InconclusivoMetanáliseAnsiedade Anandamida (AEA)
2021
Endogenous anandamide and self-reported pain are significantly reduced after a 2-week multimodal treatment with and without radon therapy in patients with knee osteoarthritis: a pilot study
InconclusivoEnsaio ClínicoArtrite Artrite — Osteoartrite Anandamida (AEA)
2021
Endogenous antagonists of N-methyl-d-aspartate receptor in schizophrenia
InconclusivoMetanálisePsicose Esquizofrenia Endocanabinoide (não especificado)
2021
Engagement patterns with a digital therapeutic for substance use disorders: Correlations with abstinence outcomes
FavorávelEnsaio ClínicoDependência Química Dependência — Cannabis Dependência — Álcool+2
2021
Engineered Lactobacillus paracasei Producing Palmitoylethanolamide (PEA) Prevents Colitis in Mice
FavorávelEstudo em AnimaisInflamação Estresse Oxidativo DII — Doença Inflamatória Intestinal Palmitoiletanolamida (PEA)
2021
Epidemiological overview of multidimensional chromosomal and genome toxicity of cannabis exposure in congenital anomalies and cancer development
DesfavorávelMetanáliseCâncer Câncer — Mama Câncer — Leucemia Canabigerol (CBG)Canabicromeno (CBC)+4
2021
Epidemiology of cannabidiol related cases reported in the National Poison Data System - 2019-2020
InconclusivoMetanáliseEfeitos Adversos da Cannabis
2021
Epidemiology of cannabis use and associated outcomes among kidney transplant recipients: A meta-analysis
InconclusivoMetanáliseRejeição de Transplante
2021
Epigenetic Regulation of Cannabinoid-Mediated Attenuation of Inflammation and Its Impact on the Use of Cannabinoids to Treat Autoimmune Diseases
FavorávelMetanáliseInflamação Esclerose Múltipla DII — Doença Inflamatória Intestinal+2
2021
Epileptic Phenotype and Cannabidiol Efficacy in a Williams–Beuren Syndrome Patient With Atypical Deletion: A Case Report
FavorávelMetanáliseEpilepsia Epilepsia — Síndrome de Dravet Epilepsia — Lennox-Gastaut CBD Farmacêutico
2021
Essential Oil from the Leaves of Chromolaena odorata, and Sesquiterpene Caryophyllene Oxide Induce Sedative Activity in Mice
InconclusivoEstudo em AnimaisInsônia e Distúrbios do Sono Outros Compostos Relacionados
2021
Essential oils as an effective alternative for the treatment of COVID-19: Molecular interaction analysis of protease (Mpro) with pharmacokinetics and toxicological properties
FavorávelEstudo LaboratorialCOVID-19
2021
Eucalyptol ameliorates early brain injury after subarachnoid haemorrhage via antioxidant and anti-inflammatory effects in a rat model
FavorávelEstudo em AnimaisInflamação Estresse Oxidativo AVC
2021
EVALI - E-Cigarette or Vaping Product Use-Associated Lung Injury: A Case Report
DesfavorávelMetanáliseEfeitos Adversos da Cannabis Lesão Pulmonar por Vaping (EVALI)Tetraidrocanabinol (THC)
2021
Evaluating cannabidiol (CBD) expectancy effects on acute stress and anxiety in healthy adults: a randomized crossover study
InconclusivoEnsaio ClínicoAnsiedade
2021
Evaluating cannabis use risk reduction as an alternative clinical outcome for cannabis use disorder.
FavorávelMetanáliseDependência Química Efeitos Adversos da Cannabis Dependência — Cannabis
2021
Evaluating the Safety of Cannabinoid-Based Medicines for Older Adults
DesfavorávelMetanáliseEfeitos Adversos da Cannabis Condições Geriátricas