Sistema Endócrino

termo de indexação original: Endocrine System

O acervo do Cannabis Indica reúne 331 estudos científicos que tocam o Sistema Endócrino, publicados entre 2000 e 2024. Pela leitura automatizada, 246 (74%) foram classificados como favoráveis, 40 (12%) como inconclusivos e 45 (14%) como desfavoráveis — uma leitura de máquina, feita para navegar, não para concluir. O desenho mais frequente é metanálise (122 estudos), seguido de estudo em animais (89). As condições mais estudadas dentro deste sistema são Obesidade, Diabetes e Síndrome Metabólica.

Estudos indexados: 331
Período coberto: 2000–2024
Favoráveis: 246 · 74%
Inconclusivos: 40 · 12%
Desfavoráveis: 45 · 14%
Termo original: Endocrine System

O acervo em números

Tipo de estudo

Metanálise122

Estudo em Animais89

Ensaio Clínico48

Ensaio Clínico Duplo-Cego37

Estudo Laboratorial27

Metanálise Clínica8

Direção do resultado

Favorável246

Inconclusivo40

Desfavorável45

Por década

2000s47

2010s157

2020s127

Aparece junto com

Obesidade137 Diabetes133 Síndrome Metabólica119 Inflamação49 Doenças Cardiovasculares (DCV)48 Câncer31 Estresse Oxidativo23 Dor21

331 estudos

Filtrar e buscar no acervo →

Esta página mostra 300 dos 331 estudos indexados sobre o tema, dos mais recentes aos mais antigos. Abra o acervo com este filtro para percorrer todos, ou baixe a lista completa em JSON e CSV.

2024
Cold-induced changes in plasma signaling lipids are associated with a healthier cardiometabolic profile independently of brown adipose tissue
FavorávelEnsaio ClínicoObesidade Diabetes Síndrome Metabólica Endocanabinoide (não especificado)Exposição ao Frio
2024
Dietary linoleic acid lowering alone does not lower arachidonic acid or endocannabinoids among women with overweight and obesity: A randomized, controlled trial
InconclusivoEnsaio ClínicoInflamação Obesidade Síndrome Metabólica Endocanabinoide (não especificado)2-Araquidonoilglicerol (2-AG)+5
2024
Examining the oleoylethanolamide supplement effects on glycemic status, oxidative stress, inflammation, and anti-mullerian hormone in polycystic ovary syndrome
FavorávelEnsaio Clínico Duplo-CegoSíndrome dos Ovários Policísticos Oleoiletanolamida (OEA)
2024
Is marijuana a foe of male sexuality? Data from a large cohort of men with sexual dysfunction
FavorávelMetanáliseLibido Disfunção Erétil
2024
Nutrient composition of different energy-restricted diets determines plasma endocannabinoid profiles and adipose tissue DAGL-α expression; a 12-week randomized controlled trial in subjects with abdominal obesity
InconclusivoEnsaio ClínicoObesidade Síndrome Metabólica Anandamida (AEA)Endocanabinoide (não especificado)+2
2024
Perioperative Cannabis Use in Bariatric Patients: A Review of Outcomes and Proposed Clinical Pathway for Management
DesfavorávelMetanáliseDor Dependência Química Efeitos Adversos da Cannabis+10
2024
Seventeen years since rimonabant's downfall: reassessing its suicidality risk profile
InconclusivoMetanáliseObesidade Tentativa de Suicídio Canabinoide Sintético (não especificado)
2024
The circulating and central endocannabinoid system in obesity and weight loss
InconclusivoMetanáliseObesidade Anandamida (AEA)Endocanabinoide (não especificado)+1
2024
Update on cannabis in human sexuality
FavorávelMetanáliseInfertilidade Masculina Libido Disfunção Erétil+1
2023
A Phase I Randomized, Double-blind, Placebo-controlled Study on Efficacy and Safety Profile of a Sublingually Administered Cannabidiol /Delta 9-tetrahydrocannabidiol (10: 1) Regimen in Diabetes Type 2 Patients
FavorávelEnsaio Clínico Duplo-CegoDiabetes Síndrome Metabólica
2023
A Randomized, Controlled Trial of Efficacy and Safety of Cannabidiol in Idiopathic and Diabetic Gastroparesis
FavorávelEnsaio Clínico Duplo-CegoDiabetes Gastroparesia Hidrolase de Amidas de Ácidos Graxos (FAAH)CBD Farmacêutico
2023
Almond Consumption for 8 Weeks Altered Host and Microbial Metabolism in Comparison to a Control Snack in Young Adults
FavorávelMetanáliseInflamação Síndrome Metabólica Endocanabinoide (não especificado)Hidrolase de Amidas de Ácidos Graxos (FAAH)+1
2023
Cannabinoid Hyperemesis Syndrome in a 23-Year-Old Woman with Uncontrolled Type 1 Diabetes Mellitus
DesfavorávelMetanáliseDor Efeitos Adversos da Cannabis Dor — Crônica Endocanabinoide (não especificado)+5
2023
Cyclodextrin Conjugated α-Bisabolol Suppresses FAK Phosphorylation and Induces Apoptosis in Pancreatic Cancer
FavorávelEstudo em AnimaisCâncer Câncer — Pâncreas
2023
Effects of CB1R inverse agonist, INV-202, in patients with features of metabolic syndrome. A randomized, placebo-controlled, double-blind phase 1b study
FavorávelEnsaio Clínico Duplo-CegoObesidade Síndrome Metabólica Endocanabinoide (não especificado)
2023
The endogenous cannabinoid system modulates male sexual behavior expression
FavorávelMetanáliseInfertilidade Masculina Libido Disfunção Erétil Endocanabinoide (não especificado)Canabinoide Sintético (não especificado)
2023
Therapeutic effect of cannabidiol on myocardial arachidonic acid content in various lipid fractions in a rat model of obesity
FavorávelEstudo em AnimaisInflamação Doenças Cardiovasculares (DCV)Estresse Oxidativo Endocanabinoide (não especificado)+4
2022
(Wh)olistic (E)ndocannabinoidome-Microbiome-Axis Modulation through (N)utrition (WHEN) to Curb Obesity and Related Disorders
FavorávelMetanáliseObesidade Diabetes Síndrome Metabólica Anandamida (AEA)Endocanabinoide (não especificado)+6
2022
A Low Dose of Pure Cannabidiol Is Sufficient to Stimulate the Cytotoxic Function of CIK Cells without Exerting the Downstream Mediators in Pancreatic Cancer Cells
FavorávelEstudo LaboratorialCâncer Inflamação Câncer — Pâncreas
2022
A randomized controlled trial assessing the safety and efficacy of palmitoylethanolamide for treating diabetic-related peripheral neuropathic pain
FavorávelEnsaio Clínico Duplo-CegoDor Inflamação Ansiedade Anandamida (AEA)Palmitoiletanolamida (PEA)+6
2022
Acute pancreatitis as a rare adverse event among cannabis users: A systematic review
DesfavorávelMetanáliseDor Inflamação Efeitos Adversos da Cannabis Anandamida (AEA)+17
2022
Analysis of 2-Arachidonoylglycerol Levels in Polycystic Ovary Syndrome in the Context of Hormonal and Metabolic Alterations and Across the Classical Phenotypes
InconclusivoMetanáliseSíndrome dos Ovários Policísticos 2-Araquidonoilglicerol (2-AG)
2022
Antitumor Effects of Cannabinoids in Human Pancreatic Ductal Adenocarcinoma Cell Line (Capan-2)-Derived Xenograft Mouse Model
FavorávelEstudo em AnimaisCâncer Câncer — Pâncreas Tetraidrocanabinol (THC)
2022
Cannabidiol Downregulates Myocardial de Novo Ceramide Synthesis Pathway in a Rat Model of High-Fat Diet-Induced Obesity
FavorávelEstudo em AnimaisDoenças Cardiovasculares (DCV)Obesidade Síndrome Metabólica
2022
Cannabidiol for the Management of Endometriosis and Chronic Pelvic Pain
InconclusivoMetanáliseDor Dor — Crônica Endometriose
2022
Cannabidiol-Treated Ovariectomized Mice Show Improved Glucose, Energy, and Bone Metabolism With a Bloom in Lactobacillus
FavorávelEstudo em AnimaisInflamação Diabetes Síndrome Metabólica+3
2022
Cannabinoid-Related Acute Pancreatitis: An Update from International Literature and Individual Case Safety Reports
DesfavorávelMetanáliseEfeitos Adversos da Cannabis Pancreatite THC Farmacêutico
2022
Cannabis sativa Extract Induces Apoptosis in Human Pancreatic 3D Cancer Models: Importance of Major Antioxidant Molecules Present Therein
FavorávelEstudo LaboratorialCâncer Inflamação Estresse Oxidativo Tetraidrocanabinol (THC)Canabigerol (CBG)+9
2022
Cannabis Use for Endometriosis: Clinical and Legal Challenges in Australia and New Zealand
FavorávelMetanáliseEndometriose
2022
Cannabis Use Is Inversely Associated with Metabolic Disorders in Hepatitis C-Infected Patients (ANRS CO22 Hepather Cohort)
FavorávelMetanáliseDoenças Cardiovasculares (DCV)Síndrome Metabólica Hipertensão Arterial+1
2022
Circulating endocannabinoid levels in pregnant women with gestational diabetes mellitus: a case-control study
DesfavorávelMetanáliseDiabetes Gestação Anandamida (AEA)2-Araquidonoilglicerol (2-AG)
2022
Cloudy with a chance of munchies: Assessing the impact of recreational marijuana legalization on obesity
FavorávelMetanáliseEfeitos Adversos da Cannabis Obesidade
2022
Curcumin Protects Diabetic Mice against Isoproterenol-Induced Myocardial Infarction by Modulating CB2 Cannabinoid Receptors
FavorávelEstudo em AnimaisDiabetes Cúrcuma
2022
Deprogramming metabolism in pancreatic cancer with a bi-functional GPR55 inhibitor and biased β2 adrenergic agonist
FavorávelEstudo LaboratorialCâncer Câncer — Mama Câncer — Cérebro Endocanabinoide (não especificado)+2
2022
Differentiating Diabetic Ketoacidosis and Hyperglycemic Ketosis Due to Cannabis Hyperemesis Syndrome in Adults With Type 1 Diabetes
InconclusivoMetanáliseEfeitos Adversos da Cannabis Diabetes Síndrome Metabólica+1
2022
Distinct Effects of Cannabidiol on Sphingolipid Metabolism in Subcutaneous and Visceral Adipose Tissues Derived from High-Fat-Diet-Fed Male Wistar Rats
FavorávelEstudo em AnimaisDiabetes Síndrome Metabólica
2022
Effects of hemp seed alone and combined with aerobic exercise on metabolic parameters, oxidative stress, and neurotrophic factors in young sedentary men
FavorávelEnsaio Clínico Duplo-CegoEstresse Oxidativo Síndrome Metabólica Exercício Físico
2022
Engaging the Endocannabinoid System in Neuroendocrine Neoplasms (NENs) potentiates treatment outcomes and null drug resistance
FavorávelEstudo LaboratorialCâncer — Neuroendócrino
2022
Exploring the endocannabinoidome in genetically obese (ob/ob) and diabetic (db/db) mice: Links with inflammation and gut microbiota
FavorávelEstudo LaboratorialInflamação Obesidade Diabetes Anandamida (AEA)Endocanabinoide (não especificado)+7
2022
Fetal Exposure to Cannabis and Childhood Metabolic Outcomes: The Healthy Start Study
DesfavorávelEnsaio ClínicoDiabetes Síndrome Metabólica Gestação Canabigerol (CBG)Canabinol (CBN)+2
2022
Frequent Cannabis Use Moderates the Relationship Between Sexual Dysfunction and Depression Among Female German Adults
DesfavorávelMetanáliseEfeitos Adversos da Cannabis Depressão Dependência — Álcool+3
2022
Geraniol ameliorates the progression of high fat-diet/streptozotocin-induced type 2 diabetes mellitus in rats via regulation of caspase-3, Bcl-2, and Bax expression
FavorávelEstudo em AnimaisDiabetes
2022
Herbal Cannabis Use Is Not Associated with Changes in Levels of Endocannabinoids and Metabolic Profile Alterations among Older Adults
InconclusivoEnsaio ClínicoInflamação Doenças Cardiovasculares (DCV)Obesidade Anandamida (AEA)Tetraidrocanabinol (THC)+7
2022
Hypoglycemic, Hypolipidemic, and Anti-Inflammatory Effects of Beta-Pinene in Diabetic Rats
FavorávelEstudo em AnimaisInflamação Diabetes Síndrome Metabólica
2022
Improved glycemic status, insulin resistance and inflammation after receiving oral oleoylethanolamide supplement in people with prediabetes: a randomized controlled trial
FavorávelEnsaio Clínico Duplo-CegoInflamação Diabetes Síndrome Metabólica Oleoiletanolamida (OEA)
2022
Inhalation of low-dose basil (Ocimum basilicum) essential oil improved cardiovascular health and plasma lipid markers in high fat diet-induced obese rats
FavorávelEstudo em AnimaisDoenças Cardiovasculares (DCV)Obesidade Síndrome Metabólica Endocanabinoide (não especificado)+1
2022
Palmitoylethanolamide dampens neuroinflammation and anxiety-like behavior in obese mice
FavorávelEstudo em AnimaisInflamação Ansiedade Doenças Neurodegenerativas Palmitoiletanolamida (PEA)+3
2022
Performance of urinary liver-type fatty acid-binding protein in diabetic nephropathy: A meta-analysis
FavorávelMetanálise ClínicaDiabetes Insuficiência Renal Doença Renal Crônica Proteína Ligadora de Ácidos Graxos (FABP)+1
2022
Rice Bran Lipidome Identifies Novel Phospholipids, Glycolipids, and Oxylipins with Roles in Lipid Metabolism of Hypercholesterolemic Children
FavorávelEnsaio ClínicoDoenças Cardiovasculares (DCV)Síndrome Metabólica Aterosclerose Endocanabinoide (não especificado)
2022
Role of the endocannabinoid system in the pathophysiology of endometriosis and therapeutic implications
FavorávelMetanáliseDor Inflamação Dor — Inflamatória Anandamida (AEA)Endocanabinoide (não especificado)+8
2022
Serum Metabolomic Analysis of Male Patients with Cannabis or Amphetamine Use Disorder
DesfavorávelEnsaio ClínicoDependência Química Efeitos Adversos da Cannabis Dependência — Cannabis+3
2022
Sex differences in endocannabinoids during 3 years of Mediterranean diet intervention: Association with insulin resistance and weight loss in a population with metabolic syndrome
FavorávelEnsaio ClínicoObesidade Diabetes Síndrome Metabólica Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+3
2022
Sex Differences in the Association Between Cannabis Use and Diabetes Mellitus among U.S. Adults: The National Health and Nutritional Examination Survey, 2013-2018
FavorávelMetanáliseDiabetes
2022
Spinal cannabinoid CB1 or CB2 receptors activation attenuates mechanical allodynia in streptozotocin-induced diabetic rats
FavorávelEstudo em AnimaisDor Dor — Crônica Diabetes Endocanabinoide (não especificado)Canabinoides Sintéticos AM-x+4
2022
Targeting the Endocannabinoid System: From the Need for New Therapies to the Development of a Promising Strategy. What About Pancreatic Cancer?
FavorávelMetanáliseDor Câncer Estresse Oxidativo Anandamida (AEA)Tetraidrocanabinol (THC)+15
2022
Targeting the Endocannabinoidome in Pancreatic Cancer
FavorávelMetanáliseCâncer Inflamação Câncer — Pâncreas Anandamida (AEA)Endocanabinoide (não especificado)+7
2022
The effect of β-caryophyllene on food addiction and its related behaviors: A randomized, double-blind, placebo-controlled trial
FavorávelEnsaio Clínico Duplo-CegoAnsiedade Depressão Obesidade Endocanabinoide (não especificado)+1
2022
The Endocannabinoid System and Physical Activity—A Robust Duo in the Novel Therapeutic Approach against Metabolic Disorders
FavorávelMetanáliseInflamação Ansiedade Doenças Cardiovasculares (DCV)Anandamida (AEA)Endocanabinoide (não especificado)+14
2022
The Metabolic Efficacy of a Cannabidiolic Acid (CBDA) Derivative in Treating Diet- and Genetic-Induced Obesity
FavorávelEstudo em AnimaisObesidade Síndrome Metabólica Canabinoides Sintéticos HU-x Ácido Canabidiólico (CBD-a)
2022
The Microbiome and Gut Endocannabinoid System in the Regulation of Stress Responses and Metabolism
FavorávelMetanáliseObesidade Síndrome Metabólica Endocanabinoide (não especificado)Microbioma
2022
Treatment of Ovarian Hyperstimulation Syndrome in a Mouse Model by Cannabidiol, an Angiogenesis Pathway Inhibitor
FavorávelEstudo em AnimaisDor Câncer Inflamação+17
2022
Vitamin D mitigates diabetes-associated metabolic and cognitive dysfunction by modulating gut microbiota and colonic cannabinoid receptor 1
FavorávelEstudo em AnimaisDisfunção Cognitiva Obesidade Diabetes Microbioma+2
2021
(+)-trans-Cannabidiol-2-hydroxy pentyl is a dual CB 1 R antagonist/CB 2 R agonist that prevents diabetic nephropathy in mice
FavorávelEstudo em AnimaisDor Diabetes Síndrome Metabólica+3
2021
A cannabinoid type 2 (CB2) receptor agonist augments NOS-dependent responses of cerebral arterioles during type 1 diabetes
FavorávelEstudo em AnimaisDiabetes Canabinoides Sintéticos JWH-x
2021
A New Clinical Utility for Tubular Markers to Identify Kidney Responders to Saxagliptin Treatment in Adults With Diabetic Nephropathy
InconclusivoEnsaio ClínicoDor Doenças Cardiovasculares (DCV)Diabetes Proteína Ligadora de Ácidos Graxos (FABP)+3
2021
Acute effects of hemp protein consumption on glycemic and satiety control: results of two randomized crossover trials
FavorávelEnsaio ClínicoObesidade Diabetes Síndrome Metabólica
2021
An Unexpected Case of Cannabis-Induced Pancreatitis
DesfavorávelMetanálisePancreatite
2021
Anti-Inflammatory and Pro-Autophagy Effects of the Cannabinoid Receptor CB2R: Possibility of Modulation in Type 1 Diabetes
FavorávelMetanáliseInflamação Esclerose Múltipla Diabetes Anandamida (AEA)Endocanabinoide (não especificado)+6
2021
Antidiabetic Potential of Naturally Occurring Sesquiterpenes: A Review
FavorávelMetanáliseDiabetes
2021
Associations of Serum Fatty Acid Proportions with Obesity, Insulin Resistance, Blood Pressure, and Fatty Liver: The Cardiovascular Risk in Young Finns Study
FavorávelMetanáliseDoenças Cardiovasculares (DCV)Obesidade Diabetes Ácido Pentadecanoico (C15:0)+4
2021
Attenuation of Oxidative Stress and Inflammatory Response by Chronic Cannabidiol Administration Is Associated with Improved n-6/n-3 PUFA Ratio in the White and Red Skeletal Muscle in a Rat Model of High-Fat Diet-Induced Obesity
FavorávelEstudo em AnimaisInflamação Estresse Oxidativo Obesidade+2
2021
Beneficial Effects of Akkermansia muciniphila Are Not Associated with Major Changes in the Circulating Endocannabinoidome but Linked to Higher Mono-Palmitoyl-Glycerol Levels as New PPARα Agonists
InconclusivoEnsaio ClínicoDoenças Cardiovasculares (DCV)Obesidade Síndrome Metabólica Endocanabinoide (não especificado)Microbioma+1
2021
Borneol protects against cerulein-induced oxidative stress and inflammation in acute pancreatitis mice model
FavorávelEstudo em AnimaisInflamação Pancreatite
2021
Caloric restriction, physical exercise, and CB1 receptor blockade as an efficient combined strategy for bodyweight control and cardiometabolic status improvement in male rats
FavorávelEstudo em AnimaisDoenças Cardiovasculares (DCV)Obesidade Diabetes Canabinoides Sintéticos AM-x Exercício Físico+1
2021
Cannabidiol - A phytocannabinoid that widely affects sphingolipid metabolism under conditions of brain insulin resistance
FavorávelEstudo em AnimaisDoenças Neurodegenerativas Obesidade Doença de Alzheimer+2
2021
Cannabis sativa as a Treatment for Obesity: From Anti-Inflammatory Indirect Support to a Promising Metabolic Re-Establishment Target
FavorávelMetanáliseInflamação Obesidade Tetraidrocanabivarina (THCV)
2021
Cannabis Use Is Inversely Associated with Overweight and Obesity in Hepatitis B Virus-Infected Patients (ANRS CO22 Hepather Cohort)
FavorávelMetanáliseObesidade Hepatite
2021
Cannabis-Induced Pancreatitis in a Young Adult Male
DesfavorávelMetanálisePancreatite
2021
Dysregulation of endocannabinoid concentrations in human subcutaneous adipose tissue in obesity and modulation by omega-3 polyunsaturated fatty acids
FavorávelEstudo LaboratorialInflamação Obesidade Síndrome Metabólica Anandamida (AEA)Endocanabinoide (não especificado)
2021
Effect of Dipeptidyl Peptidase-4 (DPP-4) Inhibition on Biomarkers of Kidney Injury and Vascular Calcification in Diabetic Kidney Disease: A Randomized Controlled Trial
FavorávelEnsaio ClínicoInflamação Diabetes Nefropatia Diabética Proteína Ligadora de Ácidos Graxos (FABP)
2021
Effect of β-Caryophyllene on insulin resistance in skeletal muscle of high fat diet and fructose-induced type-2 diabetic rats
FavorávelEstudo em AnimaisDiabetes Síndrome Metabólica
2021
Evaluation of cannabidiol's inhibitory effect on alpha-glucosidase and its stability in simulated gastric and intestinal fluids
FavorávelEstudo LaboratorialDiabetes
2021
Expression of NF-κB, IL-6, and IL-10 genes, body composition, and hepatic fibrosis in obese patients with NAFLD-Combined effects of oleoylethanolamide supplementation and calorie restriction: A triple-blind randomized controlled clinical trial
FavorávelEnsaio Clínico Duplo-CegoObesidade Insuficiência Hepática Esteatose Hepática Oleoiletanolamida (OEA)
2021
Juvenile cannabidiol chronic treatments produce robust changes in metabolic markers in adult male Wistar rats
InconclusivoEstudo em AnimaisDoenças Cardiovasculares (DCV)Diabetes Síndrome Metabólica+1
2021
Linking the Endocannabinoidome with Specific Metabolic Parameters in an Overweight and Insulin-Resistant Population: From Multivariate Exploratory Analysis to Univariate Analysis and Construction of Predictive Models
FavorávelEstudo LaboratorialInflamação Doenças Cardiovasculares (DCV)Obesidade Anandamida (AEA)Endocanabinoide (não especificado)+9
2021
Mediterranean diet consumption affects the endocannabinoid system in overweight and obese subjects: possible links with gut microbiome, insulin resistance and inflammation
FavorávelEnsaio ClínicoInflamação Obesidade Diabetes Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+3
2021
Metabolic Consequences of Gestational Cannabinoid Exposure
DesfavorávelMetanáliseDoenças Cardiovasculares (DCV)Obesidade Diabetes Anandamida (AEA)Endocanabinoide (não especificado)+4
2021
Novel CBG Derivatives Can Reduce Inflammation, Pain and Obesity
FavorávelEstudo em AnimaisDor Inflamação Dor — Crônica Canabigerol (CBG)+1
2021
Persistent Cannabis Abuse and Risk for Hospitalization for Acute Pancreatitis: A Cross-Sectional Study in United States Hospitals
DesfavorávelMetanálisePancreatite
2021
Phycocyanin inhibits pancreatic cancer metastasis via suppressing epithelial-mesenchymal transition and targeting Akt/β-catenin pathway
FavorávelEstudo em AnimaisCâncer Câncer — Metastático Câncer — Pâncreas Ficocianina
2021
The Effects of Intermittent Hypoxic-Hyperoxic Exposures on Lipid Profile and Inflammation in Patients With Metabolic Syndrome
FavorávelEnsaio ClínicoInflamação Doenças Cardiovasculares (DCV)Obesidade Hidrolase de Amidas de Ácidos Graxos (FAAH)+3
2021
The gut microbiome, endocannabinoids and metabolic disorders
FavorávelMetanáliseObesidade Diabetes Síndrome Metabólica Endocanabinoide (não especificado)Microbioma
2021
The impact of cannabis use on male sexual function: A 10-year, single-center experience
FavorávelMetanáliseLibido Disfunção Erétil
2021
The sexualised use of cannabis among young sexual minority men: "I'm actually enjoying this for the first time"
FavorávelEnsaio ClínicoLibido Disfunção Erétil
2021
The use of drug based on technologically processed antibodies to endocannabinoid receptor type 1 in the treatment of obesity in adults: results of a multicenter double blind placebo controlled randomized clinical trial
FavorávelEnsaio Clínico Duplo-CegoObesidade Endocanabinoide (não especificado)
2021
Understanding the possible role of endocannabinoid system in obesity
FavorávelMetanáliseObesidade Síndrome Metabólica Endocanabinoide (não especificado)
2021
β-caryophyllene ameliorated obesity-associated airway hyperresponsiveness through some non-conventional targets
FavorávelEstudo em AnimaisObesidade
2020
A Secondary Analysis from a Randomized Trial on the Effect of Plasma Tetrahydrocannabinol Levels on Pain Reduction in Painful Diabetic Peripheral Neuropathy
FavorávelMetanálise ClínicaDor Dor — Crônica Diabetes Tetraidrocanabinol (THC)+1
2020
A Survey Exploring the Relationship Between Cannabis Use Characteristics and Sexual Function in Men
FavorávelMetanáliseLibido Disfunção Erétil
2020
Cannabinol in the spotlight: Toxicometabolomic study and behavioral analysis of zebrafish embryos exposed to the unknown cannabinoid
DesfavorávelEstudo em AnimaisDoenças Cardiovasculares (DCV)Transtornos de Comportamento Alterações Cerebrais Neonatais Canabinol (CBN)+1
2020
Cannabis Extracts Affected Metabolic Syndrome Parameters in Mice Fed High-Fat/Cholesterol Diet
InconclusivoEstudo em AnimaisSíndrome Metabólica Esteatose Hepática Desequilíbrio do Microbioma
2020
Cannabis use is associated with a lower risk of diabetes in chronic hepatitis C-infected patients (ANRS CO22 Hepather cohort)
FavorávelMetanáliseDiabetes Fibrose Hepatite+1
2020
Cannabis Use Is Associated With Increased Risk for Diabetic Ketoacidosis in Adults With Type 1 Diabetes: Findings From the T1D Exchange Clinic Registry
DesfavorávelMetanáliseDiabetes
2020
Chronic Cannabidiol Administration Attenuates Skeletal Muscle De Novo Ceramide Synthesis Pathway and Related Metabolic Effects in a Rat Model of High-Fat Diet-Induced Obesity
FavorávelEstudo em AnimaisObesidade Diabetes Síndrome Metabólica
2020
CRISPR/Cas9 gene editing demonstrates metabolic importance of GPR55 in the modulation of GIP release and pancreatic beta cell function
FavorávelEstudo em AnimaisDiabetes Canabinoides Sintéticos AM-x Canabinoides Sintéticos O-x+1
2020
Dietary fatty acid intake and gut microbiota determine circulating endocannabinoidome signaling beyond the effect of body fat
InconclusivoEnsaio ClínicoObesidade Síndrome Metabólica Anandamida (AEA)Endocanabinoide (não especificado)+6
2020
Dietary Hemp Seeds More Effectively Attenuate Disorders in Genetically Obese Rats than Their Lipid Fraction
FavorávelEstudo em AnimaisObesidade Síndrome Metabólica
2020
Effects of a high protein/low carbohydrate low-calorie diet versus a standard low-calorie diet on anthropometric parameters and cardiovascular risk factors, role of polymorphism rs3123554 in the cannabinoid receptor gene type 2 (CB2R)
FavorávelEnsaio ClínicoInflamação Doenças Cardiovasculares (DCV)Obesidade Endocanabinoide (não especificado)+2
2020
Effects of Perioperative Cannabis Use on Bariatric Surgical Outcomes: a Systematic Review
FavorávelMetanáliseEfeitos Adversos da Cannabis Obesidade
2020
Endocannabinoid system and cardiometabolic risk factors: A comprehensive systematic review insight into the mechanistic effects of omega-3 fatty acids
FavorávelMetanáliseDoenças Cardiovasculares (DCV)Obesidade Síndrome Metabólica Anandamida (AEA)Endocanabinoide (não especificado)+3
2020
High fat-fed GPR55 null mice display impaired glucose tolerance without concomitant changes in energy balance or insulin sensitivity but are less responsive to the effects of the cannabinoids rimonabant or Δ(9)-tetrahydrocannabivarin on weight gain
FavorávelEstudo em AnimaisObesidade Diabetes Canabinoides Sintéticos SR-x Tetraidrocanabivarina (THCV)
2020
Illicit Cannabis Usage as a Management Strategy in New Zealand Women with Endometriosis: An Online Survey
FavorávelMetanáliseEndometriose
2020
Impact of a weight loss and fitness intervention on exercise-associated plasma oxylipin patterns in obese, insulin-resistant, sedentary women
FavorávelEnsaio ClínicoEstresse Oxidativo Obesidade Diabetes Anandamida (AEA)Endocanabinoide (não especificado)+4
2020
Obesity Affects the Microbiota-Gut-Brain Axis and the Regulation Thereof by Endocannabinoids and Related Mediators
FavorávelMetanáliseObesidade Desequilíbrio do Microbioma Endocanabinoide (não especificado)Microbioma
2020
Oleoylethanolamide supplementation in obese patients newly diagnosed with non-alcoholic fatty liver disease: Effects on metabolic parameters, anthropometric indices, and expression of PPAR-α, UCP1, and UCP2 genes
FavorávelEnsaio Clínico Duplo-CegoInflamação Doenças Cardiovasculares (DCV)Estresse Oxidativo Anandamida (AEA)Oleoiletanolamida (OEA)+6
2020
Olfactory Exposure to β-Caryophyllene Increases Testosterone Levels in Women's Saliva
FavorávelMetanáliseLibido
2020
Palmitoylethanolamide counteracts hepatic metabolic inflexibility modulating mitochondrial function and efficiency in diet-induced obese mice
FavorávelEstudo em AnimaisEstresse Oxidativo Diabetes Síndrome Metabólica Palmitoiletanolamida (PEA)+2
2020
Phytocannabinoids: Useful Drugs for the Treatment of Obesity? Special Focus on Cannabidiol
FavorávelMetanáliseObesidade Diabetes Síndrome Metabólica
2020
Plant-derived natural therapeutics targeting cannabinoid receptors in metabolic syndrome and its complications: A review
FavorávelMetanáliseEstresse Oxidativo Diabetes Síndrome Metabólica+2
2020
Prefrontal Cortex Neuromodulation Enhances Frontal Asymmetry and Reduces Caloric Intake in Patients with Morbid Obesity
FavorávelEnsaio Clínico Duplo-CegoObesidade Endocanabinoide (não especificado)
2020
Targeting the Endocannabinoid CB1 Receptor to Treat Body Weight Disorders: A Preclinical and Clinical Review of the Therapeutic Potential of Past and Present CB1 Drugs
FavorávelMetanáliseObesidade
2020
The effect of α-terpineol enantiomers on biomarkers of rats fed a high-fat diet
FavorávelEstudo em AnimaisInflamação Estresse Oxidativo Obesidade+2
2020
The effects of recreational cannabis use on glycemic outcomes and self-management behaviours in people with type 1 and type 2 diabetes: a rapid review
DesfavorávelMetanáliseDiabetes Síndrome Metabólica
2020
Therapeutic Potential of β-Caryophyllene: A Dietary Cannabinoid in Diabetes and Associated Complications
FavorávelMetanáliseDiabetes
2020
Whey protein supplementation reducing fasting levels of anandamide and 2-AG without weight loss in pre-menopausal women with obesity on a weight-loss diet
FavorávelEnsaio Clínico Duplo-CegoCâncer Inflamação Doenças Cardiovasculares (DCV)Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+8
2020
β-caryophyllene improves sexual performance via modulation of crucial enzymes relevant to erectile dysfunction in rats
InconclusivoEstudo em AnimaisLibido Disfunção Erétil
2020
Δ9-Tetrahydrocannabivarin (THCV): a commentary on potential therapeutic benefit for the management of obesity and diabetes
FavorávelMetanáliseObesidade Diabetes Esteatose Hepática Tetraidrocanabivarina (THCV)
2019
“HASH”ing out pancreatitis: the new increasingly common culprit
DesfavorávelMetanálisePancreatite
2019
A Rare Case of Cannabis-induced Acute Pancreatitis
DesfavorávelMetanálisePancreatite
2019
Associations Between Cannabis Use and Cardiometabolic Risk Factors: A Longitudinal Study of Men
FavorávelMetanáliseDoenças Cardiovasculares (DCV)Síndrome Metabólica
2019
Blood-brain barrier disturbances in diabetes-associated dementia: Therapeutic potential for cannabinoids.
FavorávelMetanáliseDisfunção Cognitiva Diabetes
2019
Cannabidiol improves metabolic dysfunction in middle-aged diabetic rats submitted to a chronic cerebral hypoperfusion
FavorávelEstudo em AnimaisDoenças Cardiovasculares (DCV)Diabetes
2019
Cannabidiol induces antidepressant and anxiolytic-like effects in experimental type-1 diabetic animals by multiple sites of action
FavorávelEstudo em AnimaisAnsiedade Depressão Diabetes
2019
Cannabis: From a Plant That Modulates Feeding Behaviors toward Developing Selective Inhibitors of the Peripheral Endocannabinoid System for the Treatment of Obesity and Metabolic Syndrome
FavorávelMetanáliseObesidade Diabetes Síndrome Metabólica Canabinoides Sintéticos AM-x Canabinoides Sintéticos SR-x+2
2019
Diabetes Canada Position Statement on Recreational Cannabis Use in Adults and Adolescents With Type 1 and Type 2 Diabetes
InconclusivoMetanáliseDiabetes
2019
Effect of acute Δ9-tetrahydrocannabinol administration on subjective and metabolic hormone responses to food stimuli and food intake in healthy humans: a randomized, placebo-controlled study
FavorávelEnsaio ClínicoSíndrome Metabólica Anorexia (perda de apetite)Perda de Apetite Tetraidrocanabinol (THC)THC Farmacêutico
2019
Effects of Cannabidiol on Diabetes Outcomes and Chronic Cerebral Hypoperfusion Comorbidities in Middle-Aged Rats
FavorávelEstudo em AnimaisDisfunção Cognitiva Diabetes
2019
Effects of Cannabinoids on Female Sexual Function
FavorávelMetanáliseLibido Disfunção Erétil
2019
Effects of Cannabis Use in Youth and Young Adults With Type 1 Diabetes: The Highs, the Lows, the Don't Knows
InconclusivoMetanáliseEfeitos Adversos da Cannabis Diabetes
2019
Flavonoid Derivative of Cannabis Demonstrates Therapeutic Potential in Preclinical Models of Metastatic Pancreatic Cancer
FavorávelEstudo em AnimaisCâncer Câncer — Metastático Câncer — Pâncreas
2019
How Cannabis Alters Sexual Experience: A Survey of Men and Women
FavorávelMetanáliseLibido Disfunção Erétil
2019
Lifestyle and Metabolic Syndrome: Contribution of the Endocannabinoidome
FavorávelMetanáliseSíndrome Metabólica Desequilíbrio do Microbioma Anandamida (AEA)Tetraidrocanabinol (THC)+7
2019
Lifetime marijuana use in relation to insulin resistance in lean, overweight, and obese US adults
FavorávelMetanáliseObesidade Diabetes Síndrome Metabólica
2019
N-Palmitoylethanolamide-Oxazoline Protects against Middle Cerebral Artery Occlusion Injury in Diabetic Rats by Regulating the SIRT1 Pathway
FavorávelEstudo em AnimaisInflamação Estresse Oxidativo Diabetes Palmitoiletanolamida (PEA)+1
2019
Naturally occurring compounds as pancreatic cancer therapeutic
FavorávelMetanáliseDor Câncer Insônia e Distúrbios do Sono+3
2019
Potential Use of Cannabinoids for the Treatment of Pancreatic Cancer
FavorávelMetanáliseCâncer Câncer — Pâncreas Hidrolase de Amidas de Ácidos Graxos (FAAH)Canabinoides Sintéticos AM-x+4
2019
Role of Cannabinoid Receptor Type 1 in Insulin Resistance and Its Biological Implications
FavorávelMetanáliseObesidade Diabetes Síndrome Metabólica 2-Araquidonoilglicerol (2-AG)Canabinoides Sintéticos AM-x+4
2019
Self-management strategies amongst Australian women with endometriosis: a national online survey
FavorávelMetanáliseEndometriose
2019
Self-Reported Efficacy of Cannabis for Endometriosis Pain
FavorávelMetanáliseEndometriose
2019
Tetrahydrocannabinolic acid A (THCA-A) reduces adiposity and prevents metabolic disease caused by diet-induced obesity
FavorávelEstudo em AnimaisSíndrome Metabólica Ácido Tetraidrocanabinólico (THC-a)
2019
The effects of delta-9-tetrahydrocannabinol on Krüppel-like factor-4 expression, redox homeostasis, and inflammation in the kidney of diabetic rat
FavorávelEstudo em AnimaisInflamação Diabetes Nefropatia Diabética
2019
The Expanded Endocannabinoid System/Endocannabinoidome as a Potential Target for Treating Diabetes Mellitus
FavorávelMetanáliseDiabetes Endocanabinoide (não especificado)Microbioma
2019
The influence of the fatty acid amide hydrolase 385C>A single nucleotide polymorphisms on obesity susceptibility
InconclusivoMetanáliseObesidade Endocanabinoide (não especificado)Hidrolase de Amidas de Ácidos Graxos (FAAH)
2019
The Relationship between Cannabis and Male Infertility, Sexual Health, and Neoplasm: a Systematic Review
InconclusivoMetanáliseCâncer Câncer — Próstata Infertilidade Masculina+4
2019
The Relationship between Marijuana Use Prior to Sex and Sexual Function in Women
FavorávelMetanáliseLibido Disfunção Erétil
2018
A Phytol-Enriched Diet Activates PPAR-α in the Liver and Brown Adipose Tissue to Ameliorate Obesity-Induced Metabolic Abnormalities
FavorávelEstudo em AnimaisObesidade Síndrome Metabólica
2018
A prospective and longitudinal study of plasma phospholipid saturated fatty acid profile in relation to cardiometabolic biomarkers and the risk of gestational diabetes
FavorávelMetanáliseDiabetes Síndrome Metabólica Gestação Ácido Pentadecanoico (C15:0)
2018
Association of vascular indices with novel circulating biomarkers as prognostic factors for cardiovascular complications in patients with type 2 diabetes mellitus
DesfavorávelEnsaio ClínicoInflamação Doenças Cardiovasculares (DCV)Diabetes Proteína Ligadora de Ácidos Graxos (FABP)+4
2018
Cannabinoids in health and disease: pharmacological potential in metabolic syndrome and neuroinflammation
FavorávelMetanáliseSíndrome Metabólica Perda de Apetite
2018
Chronic cannabidiol exposure promotes functional impairment in sexual behavior and fertility of male mice.
DesfavorávelEstudo em AnimaisLibido Disfunção Erétil
2018
Common polymorphism in the cannabinoid receptor gene type 2 (CB2R) rs3123554 are associated with metabolic changes after two different hypocaloric diets with different dietary fatty profiles
FavorávelEnsaio ClínicoObesidade Síndrome Metabólica
2018
Effects of a Weight Loss Program on Metabolic Syndrome, Eating Disorders and Psychological Outcomes: Mediation by Endocannabinoids?
FavorávelEnsaio ClínicoInflamação Doenças Cardiovasculares (DCV)Depressão Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+3
2018
Effects of cannabis use on body mass, fasting glucose and lipids during the first 12 months of treatment in schizophrenia spectrum disorders
InconclusivoMetanáliseEsquizofrenia Obesidade Síndrome Metabólica+1
2018
Effects of polymorphism rs3123554 in the cannabinoid receptor gene type 2 (CB2R) on metabolic and adiposity parameters after weight loss with two hypocaloric diets
FavorávelEnsaio Clínico Duplo-CegoDoenças Cardiovasculares (DCV)Obesidade Diabetes Endocanabinoide (não especificado)+2
2018
Endocannabinoids in Body Weight Control
FavorávelMetanáliseObesidade Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+7
2018
GPR55 signalling promotes proliferation of pancreatic cancer cells and tumour growth in mice, and its inhibition increases effects of gemcitabine.
FavorávelEstudo em AnimaisCâncer Câncer — Pâncreas
2018
Peripheral Endocannabinoids Associated With Energy Expenditure in Native Americans of Southwestern Heritage
FavorávelEnsaio ClínicoDoenças Cardiovasculares (DCV)Estresse Oxidativo Obesidade Anandamida (AEA)Endocanabinoide (não especificado)+6
2018
Phytol Stimulates the Browning of White Adipocytes Through the Activation of AMP-activated Protein Kinase (AMPK) α in Mice Fed High-Fat Diet
FavorávelEstudo em AnimaisObesidade Síndrome Metabólica
2018
Role of Cannabinoids in Obesity
FavorávelMetanáliseObesidade Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+3
2018
Role of Endocannabinoids on Sweet Taste Perception, Food Preference, and Obesity-related Disorders
FavorávelMetanáliseObesidade Diabetes Perda de Apetite Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+2
2018
Spirulina maxima Extract Reduces Obesity through Suppression of Adipogenesis and Activation of Browning in 3T3-L1 Cells and High-Fat Diet-Induced Obese Mice
FavorávelEstudo em AnimaisObesidade Diabetes Síndrome Metabólica Ficocianina
2018
The Inhibitory Effects of Cobalt Protoporphyrin IX and Cannabinoid 2 Receptor Agonists in Type 2 Diabetic Mice.
FavorávelEstudo em AnimaisDor Diabetes Dor — Neuropatia Diabética Canabinoides Sintéticos AM-x Canabinoides Sintéticos JWH-x
2018
Theoretical Explanation for Reduced Body Mass Index and Obesity Rates in Cannabis Users
FavorávelMetanáliseObesidade Síndrome Metabólica Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+2
2018
Δ9-Tetrahydrocannabinol Prevents Cardiovascular Dysfunction in STZ-Diabetic Wistar-Kyoto Rats.
FavorávelEstudo em AnimaisDoenças Cardiovasculares (DCV)Estresse Oxidativo Doenças Neurodegenerativas+1
2017
Ameliorative effect of borneol, a natural bicyclic monoterpene against hyperglycemia, hyperlipidemia and oxidative stress in streptozotocin-induced diabetic Wistar rats
FavorávelEstudo em AnimaisInflamação Doenças Cardiovasculares (DCV)Diabetes
2017
Association Between Marijuana Use and Sexual Frequency in the United States: A Population-Based Study
FavorávelMetanáliseLibido Disfunção Erétil
2017
Blockade of CB1 cannabinoid receptor alters gut microbiota and attenuates inflammation and diet-induced obesity.
FavorávelEstudo em AnimaisInflamação Obesidade Diabetes Canabinoides Sintéticos SR-x Microbioma+2
2017
Clinical Profile of Cannabis-Associated Acute Pancreatitis
DesfavorávelMetanálisePancreatite
2017
Dual therapy targeting the endocannabinoid system prevents experimental diabetic nephropathy.
FavorávelEstudo em AnimaisNefropatia Diabética Canabinoides Sintéticos AM-x
2017
Effect of Marijuana Use on Thyroid Function and Autoimmunity.
FavorávelMetanáliseHipertireoidismo e Doença de Graves
2017
Endocannabinoid receptor blockade increases vascular endothelial growth factor and inflammatory markers in obese women with polycystic ovary syndrome
InconclusivoEnsaio ClínicoSíndrome dos Ovários Policísticos Canabinoides Sintéticos SR-x
2017
Endocannabinoid receptor blockade reduces alanine aminotransferase in polycystic ovary syndrome independent of weight loss
InconclusivoMetanáliseSíndrome dos Ovários Policísticos Canabinoides Sintéticos SR-x
2017
Endocannabinoid system in sexual motivational processes: Is it a novel therapeutic horizon?
FavorávelMetanáliseLibido Disfunção Erétil Anandamida (AEA)Tetraidrocanabinol (THC)+3
2017
Geraniol Alleviates Diabetic Cardiac Complications: Effect on Cardiac Ischemia and Oxidative Stress
FavorávelEstudo em AnimaisDoenças Cardiovasculares (DCV)Estresse Oxidativo Diabetes+1
2017
Incretin secretion in humans is under the influence of cannabinoid receptors
InconclusivoEnsaio Clínico Duplo-CegoObesidade Síndrome Metabólica THC Farmacêutico
2017
Individual prolactin reactivity modulates response of nucleus accumbens to erotic stimuli during acute cannabis intoxication: an fMRI pilot study
FavorávelEnsaio ClínicoLibido Disfunção Erétil
2017
Masturbation to Orgasm Stimulates the Release of the Endocannabinoid 2-Arachidonoylglycerol in Humans.
FavorávelEnsaio Clínico Duplo-CegoLibido Disfunção Erétil Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+1
2017
Micronized palmitoylethanolamide/trans-polydatin treatment of endometriosis-related pain: a meta-analysis
FavorávelMetanáliseDor Dor — Crônica Endometriose Palmitoiletanolamida (PEA)
2017
Obesity-Related CKD: When Kidneys Get the Munchies
InconclusivoMetanáliseObesidade Doença Renal Crônica
2017
Peripheral cannabinoid-1 receptor blockade restores hypothalamic leptin signaling
FavorávelEstudo em AnimaisObesidade Canabinoide Sintético (não especificado)
2017
Restored Plasma Anandamide and Endometrial Expression of Fatty Acid Amide Hydrolase in Women With Polycystic Ovary Syndrome by the Combination Use of Diane-35 and Metformin
FavorávelEstudo LaboratorialSíndrome dos Ovários Policísticos Anandamida (AEA)Hidrolase de Amidas de Ácidos Graxos (FAAH)
2017
Severity and outcomes of acute alcoholic pancreatitis in cannabis users.
FavorávelMetanálisePancreatite
2017
The Anticancer Effects of Novel α-Bisabolol Derivatives Against Pancreatic Cancer
FavorávelEstudo LaboratorialCâncer Câncer — Pâncreas
2017
The Clinical Significance of Endocannabinoids in Endometriosis Pain Management
FavorávelMetanáliseEndometriose Anandamida (AEA)Tetraidrocanabinol (THC)+6
2017
The Effect of Cannabis Consumption on the Development and Severity of Acute Pancreatitis
InconclusivoMetanálisePancreatite
2016
A cross-sectional analysis of the association between marijuana and cigarette smoking with metabolic syndrome among adults in the United States
DesfavorávelMetanáliseDoenças Cardiovasculares (DCV)Síndrome Metabólica Hipertensão Arterial
2016
Cannabidiol promotes browning in 3T3-L1 adipocytes
FavorávelEstudo LaboratorialObesidade Síndrome Metabólica
2016
Decreased Expression of Fatty Acid Amide Hydrolase in Women With Polycystic Ovary Syndrome
FavorávelEstudo LaboratorialSíndrome dos Ovários Policísticos Disfunção Ovariana Hidrolase de Amidas de Ácidos Graxos (FAAH)
2016
Effects of Tangshen Formula on urinary and plasma liver-type fatty acid binding protein levels in patients with type 2 diabetic kidney disease: post-hoc findings from a multi-center, randomized, double-blind, placebo-controlled trial investigating the efficacy and safety of Tangshen Formula in patients with type 2 diabetic kidney disease
DesfavorávelMetanáliseInflamação Diabetes Insuficiência Renal Proteína Ligadora de Ácidos Graxos (FABP)+1
2016
Efficacy and Safety of Cannabidiol and Tetrahydrocannabivarin on Glycemic and Lipid Parameters in Patients With Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Pilot Study.
FavorávelEnsaio Clínico Duplo-CegoDiabetes Esteatose Hepática Tetraidrocanabivarina (THCV)
2016
Endocannabinoid receptor blockade increases hepatocyte growth factor and reduces insulin levels in obese women with polycystic ovary syndrome
FavorávelMetanáliseCâncer Inflamação Obesidade Endocanabinoide (não especificado)THC Farmacêutico+5
2016
Experimental cannabidiol treatment reduces early pancreatic inflammation in type 1 diabetes.
FavorávelEstudo em AnimaisDiabetes
2016
Fetal Syndrome of Endocannabinoid Deficiency (FSECD) In Maternal Obesity
InconclusivoMetanáliseObesidade Gestação
2016
Geraniol Improves the Impaired Vascular Reactivity in Diabetes and Metabolic Syndrome Through Calcium Channel Blocking Effect
FavorávelEstudo em AnimaisDiabetes Síndrome Metabólica
2016
Got Munchies? Estimating the Relationship between Marijuana Use and Body Mass Index.
FavorávelMetanáliseObesidade Diabetes Síndrome Metabólica+1
2016
Impact of teneligliptin on oxidative stress and endothelial function in type 2 diabetes patients with chronic kidney disease: a case-control study
FavorávelEnsaio ClínicoDoenças Cardiovasculares (DCV)Estresse Oxidativo Diabetes Proteína Ligadora de Ácidos Graxos (FABP)+3
2016
Lysophosphatidylinositol Signalling and Metabolic Diseases
DesfavorávelMetanáliseDoenças Cardiovasculares (DCV)Obesidade Diabetes Lisofosfatidilinositol (LPI)+2
2016
Marijuana Use and Type 2 Diabetes Mellitus: a Review.
FavorávelMetanáliseDiabetes
2016
Maximizing retention in long-term clinical trials of a weight loss agent: use of a dietitian support team
FavorávelEnsaio ClínicoObesidade Endocanabinoide (não especificado)Dieta
2016
Metabolic syndrome in people with a psychotic illness: is cannabis protective?
FavorávelMetanáliseSíndrome Metabólica
2016
Phycocyanin Inhibits Tumorigenic Potential of Pancreatic Cancer Cells: Role of Apoptosis and Autophagy
FavorávelEstudo em AnimaisCâncer Câncer — Pâncreas Ficocianina
2016
The novel cannabinoid antagonist SM-11 reduces hedonic aspect of food intake through a dopamine-dependent mechanism
FavorávelEstudo em AnimaisObesidade Síndrome Metabólica Canabinoide Sintético (não especificado)
2016
α-Bisabolol Inhibits Invasiveness and Motility in Pancreatic Cancer Through KISS1R Activation
FavorávelEstudo LaboratorialCâncer Câncer — Pâncreas
2015
A 4-week pilot study with the cannabinoid receptor agonist dronabinol and its effect on metabolic parameters in a randomized trial
FavorávelEnsaio Clínico Duplo-CegoDor Doenças Cardiovasculares (DCV)Dor — Aguda THC Farmacêutico+4
2015
Cannabis Smoking and Diabetes Mellitus: Results from Meta-Analysis with Eight Independent Replication Sample.
FavorávelMetanáliseDiabetes
2015
Cannabis Use and Reduced Risk of Insulin Resistance in HIV-HCV Infected Patients: A Longitudinal Analysis (ANRS CO13 HEPAVIH)
FavorávelMetanáliseDiabetes Síndrome Metabólica HIV/AIDS+1
2015
Cannabis use in relation to obesity and insulin resistance in the Inuit population.
FavorávelMetanáliseObesidade Diabetes Síndrome Metabólica
2015
Endocannabinoid system activation may be associated with insulin resistance in women with polycystic ovary syndrome
DesfavorávelMetanáliseSíndrome dos Ovários Policísticos Anandamida (AEA)2-Araquidonoilglicerol (2-AG)
2015
Palmitoylethanolamide treatment reduces retinal inflammation in streptozotocin-induced diabetic rats
FavorávelEstudo em AnimaisDor Inflamação Diabetes Palmitoiletanolamida (PEA)+2
2015
Prevention of Diet-Induced Obesity Effects on Body Weight and Gut Microbiota in Mice Treated Chronically with Δ9-Tetrahydrocannabinol.
FavorávelEstudo em AnimaisObesidade Desequilíbrio do Microbioma
2015
Reduction of serum FABP4 level by sitagliptin, a DPP-4 inhibitor, in patients with type 2 diabetes mellitus
FavorávelEnsaio ClínicoDoenças Cardiovasculares (DCV)Obesidade Diabetes Proteína Ligadora de Ácidos Graxos (FABP)+2
2015
Selected CNR1 polymorphisms and hyperandrogenemia as well as fat mass and fat distribution in women with polycystic ovary syndrome
FavorávelEstudo LaboratorialSíndrome dos Ovários Policísticos
2015
Single dose delta-9-tetrahydrocannabinol in chronic pancreatitis patients: analgesic efficacy, pharmacokinetics and tolerability
InconclusivoEnsaio Clínico Duplo-CegoDor Dor — Crônica Dependência — Opioides Canabinoide Sintético (não especificado)THC Farmacêutico+4
2014
A role for trans-caryophyllene in the moderation of insulin secretion.
FavorávelEstudo LaboratorialDiabetes
2014
Cannabinoid receptor 1 gene polymorphisms and nonalcoholic Fatty liver disease in women with polycystic ovary syndrome and in healthy controls
InconclusivoMetanáliseEsteatose Hepática Síndrome dos Ovários Policísticos
2014
Curcuminoids Target Decreasing Serum Adipocyte-fatty Acid Binding Protein Levels in Their Glucose-lowering Effect in Patients with Type 2 Diabetes
FavorávelEnsaio ClínicoInflamação Estresse Oxidativo Obesidade Cúrcuma+2
2014
Dairy fat intake is associated with glucose tolerance, hepatic and systemic insulin sensitivity, and liver fat but not β-cell function in humans
FavorávelMetanáliseDiabetes Síndrome Metabólica Esteatose Hepática Ácido Pentadecanoico (C15:0)
2014
Differences in the prospective association between individual plasma phospholipid saturated fatty acids and incident type 2 diabetes: the EPIC-InterAct case-cohort study
FavorávelMetanáliseDiabetes Síndrome Metabólica Ácido Pentadecanoico (C15:0)
2014
Emerging Issues for our Nation's Health: The Intersection of Marijuana Use and Cardiometabolic Disease Risk
InconclusivoMetanáliseSíndrome Metabólica
2014
Influence of dietary fat intake on the endocannabinoid system in lean and obese subjects
FavorávelEnsaio ClínicoInflamação Obesidade Síndrome Metabólica Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+3
2014
Moderate-vigorous physical activity across body mass index in females: moderating effect of endocannabinoids and temperament
FavorávelEnsaio ClínicoDoenças Cardiovasculares (DCV)Disfunção Cognitiva Obesidade Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+4
2014
Potential first trimester metabolomic biomarkers of abnormal birth weight in healthy pregnancies
FavorávelEnsaio ClínicoDiabetes Síndrome Metabólica Gestação Proteína Ligadora de Ácidos Graxos (FABP)
2014
Protective effects of geraniol (a monoterpene) in a diabetic neuropathy rat model: attenuation of behavioral impairments and biochemical perturbations
FavorávelEstudo em AnimaisInflamação Estresse Oxidativo Doenças Neurodegenerativas+3
2014
Repositioning therapy for thyroid cancer: new insights on established medications
FavorávelMetanáliseCâncer Câncer — Tireoide
2014
Serum pentadecanoic acid (15:0), a short-term marker of dairy food intake, is inversely associated with incident type 2 diabetes and its underlying disorders
FavorávelMetanáliseDoenças Cardiovasculares (DCV)Diabetes Aterosclerose Ácido Pentadecanoico (C15:0)
2014
The endocannabinoid system and appetite: relevance for food reward
InconclusivoMetanáliseObesidade Síndrome Metabólica Anorexia (perda de apetite)Endocanabinoide (não especificado)Canabinoide Sintético (não especificado)+2
2014
The influence of endocannabinoid receptor 1 gene variations on anthropometric and metabolic parameters of women with polycystic ovary syndrome
InconclusivoMetanáliseSíndrome dos Ovários Policísticos
2013
Antioxidative properties and inhibition of key enzymes relevant to type-2 diabetes and hypertension by essential oils from black pepper
FavorávelEstudo LaboratorialDoenças Cardiovasculares (DCV)Diabetes Hipertensão Arterial
2013
Cannabis-induced acute pancreatitis
DesfavorávelMetanálisePancreatite
2013
Cannabis: a rare cause of acute pancreatitis
DesfavorávelMetanálisePancreatite
2013
CB1 Cannabinoid Receptors Couple to Focal Adhesion Kinase to Control Insulin Release.
FavorávelEstudo em AnimaisDiabetes Anandamida (AEA)Endocanabinoide (não especificado)+7
2013
Chronic treatment with krill powder reduces plasma triglyceride and anandamide levels in mildly obese men
FavorávelEnsaio ClínicoObesidade Ômega-3
2013
Comparative proteomic and phosphoproteomic profiling of pancreatic adenocarcinoma cells treated with CB1 or CB2 agonists
FavorávelEstudo LaboratorialCâncer Câncer — Pâncreas Canabinoide Sintético (não especificado)
2013
Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity
FavorávelEstudo em AnimaisInflamação Obesidade Diabetes Endocanabinoide (não especificado)2-Araquidonoilglicerol (2-AG)+3
2013
Fat to treat fat: Emerging relationship between dietary PUFA, endocannabinoids, and obesity
FavorávelMetanáliseObesidade Síndrome Metabólica Dieta
2013
Metabolic effects of chronic cannabis smoking
DesfavorávelEnsaio ClínicoEfeitos Adversos da Cannabis Doenças Cardiovasculares (DCV)Diabetes+3
2013
Preventive and ameliorating effects of citrus D-limonene on dyslipidemia and hyperglycemia in mice with high-fat diet-induced obesity
FavorávelEstudo em AnimaisObesidade Diabetes Síndrome Metabólica
2013
The cannabinoid Δ9-tetrahydrocannabivarin (THCV) ameliorates insulin sensitivity in two mouse models of obesity.
FavorávelEstudo em AnimaisObesidade Diabetes Canabinoides Sintéticos AM-x Tetraidrocanabivarina (THCV)
2013
The impact of marijuana use on glucose, insulin, and insulin resistance among US adults.
FavorávelMetanáliseObesidade Diabetes Síndrome Metabólica
2012
A systematic review and mixed treatment comparison of pharmacological interventions for the treatment of obesity
DesfavorávelMetanálise ClínicaObesidade Canabinoides Sintéticos SR-x
2012
Additive renoprotective effects of aliskiren on angiotensin receptor blocker and calcium channel blocker treatments for type 2 diabetic patients with albuminuria
FavorávelEnsaio ClínicoDoenças Cardiovasculares (DCV)Estresse Oxidativo Diabetes Proteína Ligadora de Ácidos Graxos (FABP)+3
2012
Cannabinoid Receptor 1 Blockade Ameliorates Albuminuria in Experimental Diabetic Nephropathy.
FavorávelEstudo em AnimaisNefropatia Diabética Canabinoides Sintéticos AM-x
2012
CB(1) blockade-induced weight loss over 48 weeks decreases liver fat in proportion to weight loss in humans
FavorávelEnsaio ClínicoObesidade Insuficiência Hepática Esteatose Hepática Endocanabinoide (não especificado)Canabinoide Sintético (não especificado)
2012
Crosstalk between the gut microbiota and the endocannabinoid system: impact on the gut barrier function and the adipose tissue
FavorávelMetanáliseInflamação Obesidade Diabetes Endocanabinoide (não especificado)Microbioma+1
2012
Decreased prevalence of diabetes in marijuana users: cross-sectional data from the National Health and Nutrition Examination Survey (NHANES) III.
FavorávelMetanáliseDiabetes
2012
Efficacy of rimonabant in obese patients with binge eating disorder
FavorávelEnsaio Clínico Duplo-CegoObesidade Síndrome Metabólica Intoxicação por Cannabis Sintética Endocanabinoide (não especificado)Canabinoide Sintético (não especificado)+1
2012
Fatty acid flux and oxidation are increased by rimonabant in obese women
FavorávelEnsaio ClínicoEstresse Oxidativo Obesidade Intoxicação por Cannabis Sintética Canabinoide Sintético (não especificado)Canabinoides Sintéticos SR-x
2012
Long-term fenofibrate therapy increases fibroblast growth factor 21 and retinol-binding protein 4 in subjects with type 2 diabetes
DesfavorávelEnsaio Clínico Duplo-CegoInflamação Doenças Cardiovasculares (DCV)Obesidade Endocanabinoide (não especificado)Proteína Ligadora de Ácidos Graxos (FABP)+2
2012
Progesterone-dependent Regulation of Endometrial Cannabinoid Receptor Type 1 (CB1-R) Expression is Disrupted in Women with Endometriosis and in Isolated Stromal Cells Exposed to TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin)
InconclusivoEstudo LaboratorialEndometriose
2012
Protective effects of alpha-pinene in mice with cerulein-induced acute pancreatitis
FavorávelEstudo em AnimaisPancreatite
2012
Rimonabant improves obesity but not the overall cardiovascular risk and quality of life; results from CARDIO-REDUSE (CArdiometabolic Risk reDuctIOn by Rimonabant: the Effectiveness in Daily practice and its USE)
FavorávelEnsaio ClínicoDoenças Cardiovasculares (DCV)Obesidade Diabetes Canabinoide Sintético (não especificado)Canabinoides Sintéticos SR-x+2
2012
The l-α-Lysophosphatidylinositol/GPR55 System and Its Potential Role in Human Obesity
FavorávelEnsaio ClínicoObesidade Diabetes Síndrome Metabólica Endocanabinoide (não especificado)Lisofosfatidilinositol (LPI)
2012
The role of the endocannabinoid system in skeletal muscle and metabolic adaptations to exercise: potential implications for the treatment of obesity
FavorávelMetanáliseObesidade Síndrome Metabólica Anandamida (AEA)Exercício Físico
2011
Adipose tissue endocannabinoid system gene expression: depot differences and effects of diet and exercise
FavorávelEnsaio ClínicoDoenças Cardiovasculares (DCV)Obesidade Diabetes Anandamida (AEA)Endocanabinoide (não especificado)+5
2011
An overview of the metabolic effects of rimonabant in randomized controlled trials: potential for other cannabinoid 1 receptor blockers in obesity
InconclusivoMetanálise ClínicaObesidade Canabinoide Sintético (não especificado)
2011
Antitumor effects of α-bisabolol against pancreatic cancer
FavorávelEstudo em AnimaisCâncer Câncer — Pâncreas
2011
Cannabinoids and Endocannabinoids in Metabolic Disorders with Focus on Diabetes
FavorávelMetanáliseObesidade Diabetes Síndrome Metabólica Anandamida (AEA)Endocanabinoide (não especificado)+1
2011
Effects of lipid-lowering therapy with rosuvastatin on kidney function and oxidative stress in patients with diabetic nephropathy
FavorávelEnsaio ClínicoInflamação Doenças Cardiovasculares (DCV)Estresse Oxidativo Proteína Ligadora de Ácidos Graxos (FABP)+6
2011
Effects of the cannabinoid-1 receptor antagonist rimonabant on psychiatric symptoms in overweight people with schizophrenia: a randomized, double-blind, pilot study
DesfavorávelEnsaio Clínico Duplo-CegoEsquizofrenia Obesidade THC Farmacêutico
2011
Obesity and cannabis use: results from 2 representative national surveys.
FavorávelMetanáliseObesidade
2011
Serum A-FABP is increased and closely associated with elevated NT-proBNP levels in type 2 diabetic patients treated with rosiglitazone
DesfavorávelEnsaio ClínicoDoenças Cardiovasculares (DCV)Diabetes Síndrome Metabólica Proteína Ligadora de Ácidos Graxos (FABP)
2011
The fatty acid amide hydrolase (FAAH) gene variant rs324420 AA/AC is not associated with weight loss in a 1-year lifestyle intervention for obese children and adolescents
InconclusivoEnsaio ClínicoObesidade Hidrolase de Amidas de Ácidos Graxos (FAAH)
2010
A clinical trial assessing the safety and efficacy of taranabant, a CB1R inverse agonist, in obese and overweight patients: a high-dose study
DesfavorávelEnsaio Clínico Duplo-CegoObesidade Canabinoide Sintético (não especificado)
2010
A clinical trial assessing the safety and efficacy of the CB1R inverse agonist taranabant in obese and overweight patients: low-dose study
InconclusivoEnsaio Clínico Duplo-CegoObesidade
2010
A metabolically stable analogue of anandamide, Met-F-AEA, inhibits human thyroid carcinoma cell lines by activation of apoptosis.
FavorávelEstudo LaboratorialCâncer Câncer — Tireoide Anandamida (AEA)Endocanabinoide (não especificado)
2010
A one-year study to assess the safety and efficacy of the CB1R inverse agonist taranabant in overweight and obese patients with type 2 diabetes
DesfavorávelEnsaio Clínico Duplo-CegoObesidade Diabetes
2010
A randomized trial of lifestyle modification and taranabant for maintaining weight loss achieved with a low-calorie diet
InconclusivoEnsaio Clínico Duplo-CegoObesidade
2010
Antiproliferative Effects of Cannabinoid Agonists on Deep Infiltrating Endometriosis.
FavorávelEstudo em AnimaisEndometriose Canabinoides Sintéticos WIN-x
2010
Cannabidiol attenuates cardiac dysfunction, oxidative stress, fibrosis, inflammatory and cell death signaling pathways in diabetic cardiomyopathy.
FavorávelEstudo em AnimaisInflamação Doenças Cardiovasculares (DCV)Estresse Oxidativo+1
2010
Effect of palmitoylethanolamide-polydatin combination on chronic pelvic pain associated with endometriosis: preliminary observations
FavorávelEnsaio ClínicoDistúrbios Menstruais Infecção Urinária Endometriose Palmitoiletanolamida (PEA)
2010
Endocannabinoid involvement in endometriosis.
FavorávelEstudo em AnimaisEndometriose Endocanabinoide (não especificado)Canabinoides Sintéticos AM-x+1
2010
Polymorphisms in the endocannabinoid receptor 1 in relation to fat mass distribution
DesfavorávelEnsaio ClínicoObesidade Diabetes
2010
Psychiatric adverse effects of rimonobant in adults with Prader Willi syndrome
DesfavorávelEnsaio Clínico Duplo-CegoObesidade Canabinoide Sintético (não especificado)
2010
The endocannabinoid system links gut microbiota to adipogenesis
FavorávelEstudo em AnimaisObesidade Desequilíbrio do Microbioma Canabinoides Sintéticos SR-x Canabinoides Sintéticos HU-x+1
2009
Cannabidiol Arrests Onset of Autoimmune Diabetes in NOD Mice.
FavorávelEstudo em AnimaisDiabetes
2009
Cannabinoid CB(1) receptor activation stimulates neurite outgrowth and inhibits capsaicin-induced Ca(2+) influx in an in vitro model of diabetic neuropathy.
FavorávelEstudo LaboratorialDor Diabetes Dor — Neuropatia Diabética Canabinoides Sintéticos AM-x Canabinoides Sintéticos HU-x
2009
Drug reimbursement and GPs' prescribing decisions: a randomized case-vignette study about the pharmacotherapy of obesity associated with type 2 diabetes: how GPs react to drug reimbursement
DesfavorávelEnsaio ClínicoObesidade Diabetes
2009
Effect of rimonabant on glycemic control in insulin-treated type 2 diabetes: the ARPEGGIO trial
InconclusivoEnsaio Clínico Duplo-CegoDiabetes Canabinoide Sintético (não especificado)
2009
Endocannabinoids may mediate the ability of (n-3) fatty acids to reduce ectopic fat and inflammatory mediators in obese Zucker rats
FavorávelEstudo em AnimaisObesidade Diabetes Síndrome Metabólica Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+1
2008
A Comparative Study on Cannabidiol-Induced Apoptosis in Murine Thymocytes and EL-4 Thymoma Cells
FavorávelEstudo LaboratorialCâncer Câncer — Timo
2008
A Pilot Study of Perillyl Alcohol in Pancreatic Cancer
FavorávelEnsaio ClínicoCâncer Câncer — Pâncreas
2008
Cannabinoid 2 receptor induction by IL-12 and its potential as a therapeutic target for the treatment of anaplastic thyroid carcinoma.
FavorávelEstudo LaboratorialCâncer Câncer — Tireoide Canabinoides Sintéticos WIN-x Canabinoides Sintéticos JWH-x
2008
Cannabinoids in pancreatic cancer: Correlation with survival and pain
FavorávelEstudo LaboratorialCâncer Câncer — Pâncreas Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+2
2008
Cannabinoids Reduce Markers of Inflammation and Fibrosis in Pancreatic Stellate Cells.
FavorávelEstudo LaboratorialPancreatite Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+2
2008
Cost-effectiveness of pharmacological anti-obesity treatments: a systematic review
DesfavorávelMetanálise ClínicaObesidade Canabinoides Sintéticos SR-x
2008
Dual, time-dependent deleterious and protective effect of anandamide on the course of cerulein-induced acute pancreatitis. Role of sensory nerves.
FavorávelEstudo em AnimaisPancreatite Anandamida (AEA)
2008
Effect of rimonabant on the high-triglyceride/ low-HDL-cholesterol dyslipidemia, intraabdominal adiposity, and liver fat: the ADAGIO-Lipids trial
FavorávelEnsaio Clínico Duplo-CegoObesidade Canabinoide Sintético (não especificado)
2008
Influence of taranabant, an orally active, highly selective, potent cannabinoid-1 receptor (CB1R) inverse agonist, on ethinyl estradiol and norelgestromin plasma pharmacokinetics
FavorávelEnsaio Clínico Duplo-CegoObesidade Gestação Canabinoide Sintético (não especificado)
2008
Long-term effect of CB1 blockade with rimonabant on cardiometabolic risk factors: two year results from the RIO-Europe Study
FavorávelEnsaio Clínico Duplo-CegoObesidade
2008
Multiple-dose pharmacokinetics, pharmacodynamics, and safety of taranabant, a novel selective cannabinoid-1 receptor inverse agonist, in healthy male volunteers
DesfavorávelEnsaio ClínicoObesidade Canabinoide Sintético (não especificado)

Perguntas frequentes

Quantos estudos sobre sistema endócrino estão indexados no acervo?

São 331 estudos, publicados entre 2000 e 2024. O acervo inteiro tem 7.640 registros.

Que tipos de estudo predominam?

Metanálise: 122 · Estudo em Animais: 89 · Ensaio Clínico: 48 · Ensaio Clínico Duplo-Cego: 37 · Estudo Laboratorial: 27 · Metanálise Clínica: 8. A classificação segue o desenho declarado na fonte.

O que significa a classificação de resultado?

É uma leitura automatizada da conclusão de cada estudo, em três direções — favorável, inconclusivo e desfavorável. Aqui são 246 favoráveis, 40 inconclusivos e 45 desfavoráveis. Serve para navegar o acervo, não para concluir nada clinicamente: a conclusão válida é a do artigo original.

Como citar esta página

ABNT

CANNABIS INDICA. Sistema Endócrino — estudos científicos sobre cannabis. 2026. Disponível em: https://cannabisindica.com.br/sistema/sistema-endocrino/. Acesso em: 13 set. 2026.

APA

Cannabis Indica. (2026). Sistema Endócrino — estudos científicos sobre cannabis. https://cannabisindica.com.br/sistema/sistema-endocrino/

Esta página é um índice de acesso. Ao usar um estudo como evidência, cite o artigo original — o link de cada registro leva à fonte.