Sistema Reprodutor

termo de indexação original: Reproductive System

O acervo do Cannabis Indica reúne 341 estudos científicos que tocam o Sistema Reprodutor, publicados entre 1847 e 2024. Pela leitura automatizada, 166 (49%) foram classificados como favoráveis, 73 (21%) como inconclusivos e 102 (30%) como desfavoráveis — uma leitura de máquina, feita para navegar, não para concluir. O desenho mais frequente é metanálise (161 estudos), seguido de estudo laboratorial (84). As condições mais estudadas dentro deste sistema são Gestação, Câncer e Câncer — Mama.

Estudos indexados: 341
Período coberto: 1847–2024
Favoráveis: 166 · 49%
Inconclusivos: 73 · 21%
Desfavoráveis: 102 · 30%
Termo original: Reproductive System

O acervo em números

Tipo de estudo

Metanálise161

Estudo Laboratorial84

Estudo em Animais66

Ensaio Clínico21

Ensaio Clínico Duplo-Cego6

Metanálise Clínica3

Direção do resultado

Favorável166

Inconclusivo73

Desfavorável102

Por década

1840s1

1860s1

1980s9

1990s12

2000s33

2010s129

2020s156

Aparece junto com

Gestação155 Câncer126 Câncer — Mama73 Alterações Cerebrais Neonatais35 Infertilidade Masculina32 Libido28 Disfunção Erétil26 Câncer — Próstata25

341 estudos

Filtrar e buscar no acervo →

Esta página mostra 300 dos 341 estudos indexados sobre o tema, dos mais recentes aos mais antigos. Abra o acervo com este filtro para percorrer todos, ou baixe a lista completa em JSON e CSV.

2024
Cannabidiol-Only Product Use in Pregnancy in the United States and Canada: Findings From the International Cannabis Policy Study
DesfavorávelMetanáliseGestação
2024
Is marijuana a foe of male sexuality? Data from a large cohort of men with sexual dysfunction
FavorávelMetanáliseLibido Disfunção Erétil
2024
Morphological and clinical findings in placentas and newborns with a history of tobacco, alcohol, and other substance abuse during pregnancy
DesfavorávelMetanáliseDependência Química Dependência — Cannabis Dependência — Álcool+3
2024
Psychosexual dysfunction in male patients with cannabis dependence and synthetic cannabinoid dependence
DesfavorávelMetanáliseDependência Química Dependência — Cannabis Libido Canabinoide Sintético (não especificado)+1
2024
Relationship Between Cannabis Use and Erectile Dysfunction: A Systematic Review and Meta-Analysis
DesfavorávelMetanáliseLibido Disfunção Erétil
2024
Systematic review: the impact of maternal pre-and postnatal cannabis use on the behavioral and emotional regulation in early childhood
DesfavorávelMetanáliseGestação Transtornos de Comportamento Alterações Cerebrais Neonatais Endocanabinoide (não especificado)
2024
The association between prenatal cannabis use and congenital birth defects in offspring: A cumulative meta-analysis
DesfavorávelMetanáliseGestação Alterações Cerebrais Neonatais
2024
The impact of cannabis use on erectile dysfunction and sex hormones: a Mendelian randomization analysis
InconclusivoMetanáliseInfertilidade Masculina Libido Disfunção Erétil+1
2024
Update on cannabis in human sexuality
FavorávelMetanáliseInfertilidade Masculina Libido Disfunção Erétil+1
2023
Anti-proliferative effect of Cannabidiol in Prostate cancer cell PC3 is mediated by apoptotic cell death, NFκB activation, increased oxidative stress, and lower reduced glutathione status
FavorávelEstudo LaboratorialCâncer Câncer — Próstata
2023
CBD-oil as a potential solution in case of severe tamoxifen-related side effects
FavorávelEnsaio ClínicoDor Câncer Insônia e Distúrbios do Sono+3
2023
Could cannabinoids provide a new hope for ovarian cancer patients?
FavorávelMetanáliseDor Câncer Inflamação Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+25
2023
Financial incentives for smoking cessation in pregnancy: multicentre randomised controlled trial
FavorávelEnsaio ClínicoDependência Química Efeitos Adversos da Cannabis Dependência — Cannabis+3
2023
Interventions Addressing Cannabis Use During Pregnancy: A Systematic Review
FavorávelMetanáliseDependência Química Efeitos Adversos da Cannabis Dependência — Cannabis+1
2023
Paternal preconception modifiable risk factors for adverse pregnancy and offspring outcomes: a review of contemporary evidence from observational studies
DesfavorávelMetanáliseDependência Química Efeitos Adversos da Cannabis Dependência — Álcool+2
2023
Prenatal Exposure to Δ9-Tetrahydrocannabinol Affects Hippocampus-Related Cognitive Functions in the Adolescent Rat Offspring: Focus on Specific Markers of Neuroplasticity
DesfavorávelEstudo em AnimaisDisfunção Cognitiva Gestação Transtornos de Comportamento Tetraidrocanabinol (THC)Endocanabinoide (não especificado)+2
2023
Prenatal THC exposure induces long-term, sex-dependent cognitive dysfunction associated with lipidomic and neuronal pathology in the prefrontal cortex-hippocampal network
DesfavorávelEstudo em AnimaisEfeitos Adversos da Cannabis Disfunção Cognitiva Psicose Tetraidrocanabinol (THC)Endocanabinoide (não especificado)+2
2023
Systematic Review: Polysubstance Prevalence Estimates Reported during Pregnancy, US, 2009-2020
InconclusivoMetanáliseDependência Química Dependência — Cannabis Dependência — Álcool+2
2023
The endogenous cannabinoid system modulates male sexual behavior expression
FavorávelMetanáliseInfertilidade Masculina Libido Disfunção Erétil Endocanabinoide (não especificado)Canabinoide Sintético (não especificado)
2022
A Coala-T-Cannabis Survey Study of breast cancer patients' use of cannabis before, during, and after treatment
FavorávelMetanáliseDor Câncer Ansiedade+6
2022
A survey of medical cannabis use during perimenopause and postmenopause
InconclusivoMetanáliseAnsiedade Insônia e Distúrbios do Sono Menopausa Endocanabinoide (não especificado)+1
2022
Activation of cannabinoid receptors in breast cancer cells improves osteoblast viability in cancer-bone interaction model while reducing breast cancer cell survival and migration
FavorávelEstudo LaboratorialCâncer Câncer — Mama Câncer — Metastático Anandamida (AEA)Endocanabinoide (não especificado)+3
2022
Addiction and human male fertility: A systematic review and a critical appraisal
DesfavorávelMetanáliseDependência Química Dependência — Cannabis Dependência — Opioides+4
2022
Adverse events of recreational cannabis use during pregnancy reported to the French Addictovigilance Network between 2011 and 2020
DesfavorávelEnsaio ClínicoDependência Química Efeitos Adversos da Cannabis Dependência — Cannabis+13
2022
An In Silico Investigation to Explore Anti-Cancer Potential of Foeniculum vulgare Mill. Phytoconstituents for the Management of Human Breast Cancer
FavorávelEstudo LaboratorialCâncer Câncer — Mama
2022
Anti-cancer potential of cannabis terpenes in a Taxol-resistant model of breast cancer
FavorávelEstudo LaboratorialCâncer Câncer — Mama
2022
Anticancer activity of linalool: comparative investigation of ultrastructural changes and apoptosis in breast cancer cells
FavorávelEstudo LaboratorialCâncer Câncer — Mama Endocanabinoide (não especificado)
2022
Association between cannabis use with urological cancers: A population-based cohort study and a mendelian randomization study in the UK biobank
FavorávelMetanáliseCâncer Câncer — Próstata Câncer — Bexiga+1
2022
Association Between Prenatal Cannabis Use and Psychotropic Medication Use in Pregnant Patients With Depression and Anxiety
DesfavorávelMetanáliseDependência Química Dependência — Cannabis Ansiedade+3
2022
Birth Outcomes of Neonates Exposed to Marijuana in Utero: A Systematic Review and Meta-analysis
DesfavorávelMetanáliseGestação
2022
Breastfeeding while on treatment with antiseizure medications: a systematic review from the ILAE Women Task Force
FavorávelMetanálise ClínicaEfeitos Adversos da Cannabis Epilepsia Gestação
2022
Cannabidiol Antiproliferative Effect in Triple-Negative Breast Cancer MDA-MB-231 Cells Is Modulated by Its Physical State and by IGF-1
FavorávelEstudo LaboratorialCâncer Câncer — Mama
2022
Cannabidiol reverses memory impairments and activates components of the Akt/GSK3β pathway in an experimental model of estrogen depletion
FavorávelEstudo em AnimaisDisfunção Cognitiva Doença de Alzheimer Menopausa
2022
Cannabidiol-Treated Ovariectomized Mice Show Improved Glucose, Energy, and Bone Metabolism With a Bloom in Lactobacillus
FavorávelEstudo em AnimaisInflamação Diabetes Síndrome Metabólica+3
2022
Cannabis legalization and cannabis-involved pregnancy hospitalizations in Colorado
DesfavorávelMetanáliseEfeitos Adversos da Cannabis Gestação
2022
Cannabis with breast cancer treatment: propitious or pernicious?
DesfavorávelEstudo LaboratorialCâncer Câncer — Mama
2022
CBD activation of TRPV1 induces oxidative signaling and subsequent ER stress in breast cancer cell lines
FavorávelEstudo LaboratorialCâncer Estresse Oxidativo Câncer — Mama Endocanabinoide (não especificado)
2022
Chronic Administration of Cannabinoid Receptor 2 Agonist (JWH-133) Increases Ectopic Ovarian Tumor Growth and Endocannabinoids (Anandamide and 2-Arachidonoyl Glycerol) Levels in Immunocompromised SCID Female Mice
DesfavorávelEstudo em AnimaisCâncer Câncer — Ovário Canabinoides Sintéticos JWH-x
2022
Circulating endocannabinoid levels in pregnant women with gestational diabetes mellitus: a case-control study
DesfavorávelMetanáliseDiabetes Gestação Anandamida (AEA)2-Araquidonoilglicerol (2-AG)
2022
Clinician responses to cannabis use during pregnancy and lactation: a systematic review and integrative mixed-methods research synthesis
InconclusivoMetanáliseEfeitos Adversos da Cannabis Gestação
2022
Daily Consumption of Lemon and Ginger Herbal Infusion Caused Tumor Regression and Activation of the Immune System in a Mouse Model of Breast Cancer
FavorávelEstudo em AnimaisCâncer Câncer — Mama
2022
Decreasing sperm quality in mice subjected to chronic cannabidiol exposure: New insights of cannabidiol-mediated male reproductive toxicity
DesfavorávelEstudo em AnimaisEstresse Oxidativo Infertilidade Masculina Libido Endocanabinoide (não especificado)+1
2022
Different Cytotoxic Effects of Vetiver Oil on Three Types of Cancer Cells, Mainly Targeting CNR2 on TNBC
FavorávelEstudo LaboratorialCâncer Câncer — Mama
2022
Down-regulation of cyclooxygenase-2 (COX-2) by cannabidiolic acid in human breast cancer cells
FavorávelEstudo LaboratorialCâncer Câncer — Mama Ácido Canabidiólico (CBD-a)
2022
Frequent Cannabis Use Moderates the Relationship Between Sexual Dysfunction and Depression Among Female German Adults
DesfavorávelMetanáliseEfeitos Adversos da Cannabis Depressão Dependência — Álcool+3
2022
Geospatiotemporal and causal inference study of cannabis and other drugs as risk factors for female breast cancer USA 2003–2017
DesfavorávelMetanáliseCâncer Dependência — Álcool Câncer — Mama Canabigerol (CBG)
2022
Impact of cannabinoids on pregnancy, reproductive health and offspring outcomes
DesfavorávelMetanáliseDor Dependência Química Câncer THC:CBD Farmacêutico+15
2022
Improved Therapeutic Efficacy of CBD with Good Tolerance in the Treatment of Breast Cancer through Nanoencapsulation and in Combination with 20(S)-Protopanaxadiol (PPD)
FavorávelEstudo LaboratorialDor Câncer Ansiedade+4
2022
In vitro evaluation of the interaction of the cannabis constituents cannabichromene and cannabichromenic acid with ABCG2 and ABCB1 transporters
FavorávelEstudo LaboratorialCâncer Inflamação Depressão Canabicromeno (CBC)Ácido Canabicromênico (CBC-a)+2
2022
Inhibition of monoacylglycerol lipase restrains proliferation, migration, invasion, tumor growth and induces apoptosis in cervical cancer
FavorávelEstudo LaboratorialCâncer Câncer — Colo do Útero Monoacilglicerol Lipase (MAGL)
2022
Inhibition of triple negative breast cancer-associated inflammation, tumor growth and brain colonization by targeting monoacylglycerol lipase
FavorávelEstudo LaboratorialCâncer Câncer — Mama Monoacilglicerol Lipase (MAGL)
2022
Investigation of the Effects of the Endogenous Cannabinoid Anandamide on Luminal A Breast Cancer Cell Line MCF-7
FavorávelEstudo LaboratorialCâncer Câncer — Mama Anandamida (AEA)Endocanabinoide (não especificado)
2022
Long-term effects of prenatal cannabis exposure: Pathways to adolescent and adult outcomes
DesfavorávelMetanáliseDisfunção Cognitiva Psicose Dependência — Opioides+6
2022
Maternal trajectories of cannabis use and young adult cannabis and nicotine dependence
DesfavorávelMetanáliseDependência Química Dependência — Cannabis Dependência — Opioides+5
2022
Maternal-fetal transmission of delta-9-tetrahydrocannabinol (THC) and its metabolites following inhalation and injection exposure during pregnancy in rats
InconclusivoEstudo em AnimaisGestação Alterações Cerebrais Neonatais
2022
Patterns of Use and Self-reported Effectiveness of Cannabis for Hyperemesis Gravidarum
FavorávelMetanáliseEfeitos Adversos da Cannabis Náusea e Vômito Gestação Tetraidrocanabinol (THC)+1
2022
Phytocannabinoid Compositions from Cannabis Act Synergistically with PARP1 Inhibitor against Ovarian Cancer Cells In Vitro and Affect the Wnt Signaling Pathway
FavorávelEstudo LaboratorialCâncer Câncer — Ovário Câncer — Colo do Útero Tetraidrocanabinol (THC)Canabigerol (CBG)+3
2022
Pneumopericardium, Epidural Pneumatosis, and Muscular Emphysema: Rare Complications of Spontaneous Pneumomediastinum Due to Refractory Hyperemesis Gravidarum
DesfavorávelMetanáliseEfeitos Adversos da Cannabis Náusea e Vômito Gestação+2
2022
Potential protective effect of beta-caryophyllene against cadmium chloride-induced damage to the male reproductive system in mouse
FavorávelEstudo LaboratorialInflamação Estresse Oxidativo Infertilidade Masculina
2022
Pregnant People's Perspectives On Cannabis Use During Pregnancy: A Systematic Review and Integrative Mixed-Methods Research Synthesis
FavorávelMetanáliseDor Dependência Química Efeitos Adversos da Cannabis+8
2022
Prenatal cannabis exposure predicts attention problems, without changes on fMRI in adolescents
DesfavorávelEnsaio ClínicoDisfunção Cognitiva Gestação Transtornos de Comportamento+2
2022
Prenatal Nicotine or Cannabis Exposure and Offspring Neurobehavioral Outcomes
InconclusivoMetanáliseDependência Química Disfunção Cognitiva Síndrome Metabólica+4
2022
Role of Caryophyllane Sesquiterpenes in the Entourage Effect of Felina 32 Hemp Inflorescence Phytocomplex in Triple Negative MDA-MB-468 Breast Cancer Cells
FavorávelEstudo LaboratorialCâncer Câncer — Mama Canabicromeno (CBC)
2022
Spirulina phycocyanin extract and its active components suppress epithelial-mesenchymal transition process in endometrial cancer via targeting TGF-beta1/SMAD4 signaling pathway
FavorávelEstudo em AnimaisCâncer Câncer — Útero Ficocianina
2022
The endocannabinoids anandamide and 2-arachidonoylglycerol modulate the expression of angiogenic factors on HTR8/SVneo placental cells
InconclusivoEstudo LaboratorialGestação Anandamida (AEA)Endocanabinoide (não especificado)+1
2022
The Liberalization of Cannabis Possession Laws and Birth Outcomes: A State-Level Fixed Effects Analysis, 2003–2019
InconclusivoMetanáliseGestação
2022
The perceptions and beliefs of cannabis use among Canadian genitourinary cancer patients
FavorávelMetanáliseCâncer Câncer — Próstata Câncer — Bexiga+1
2022
The protective effect of C-phycocyanin in male mouse reproductive system
FavorávelEstudo em AnimaisInfertilidade Masculina Ficocianina
2021
Activation of the cannabinoid receptor type 2 by the agonist JWH133 promotes the first wave of in vitro spermatogenesis
FavorávelEstudo LaboratorialCâncer Infertilidade Masculina Canabinoides Sintéticos JWH-x
2021
Addictive behaviors across the menstrual cycle: a systematic review
InconclusivoMetanáliseDependência Química Transtornos de Comportamento Distúrbios Menstruais
2021
An Update on Perinatal Cannabis Use
DesfavorávelMetanáliseGestação Alterações Cerebrais Neonatais
2021
Anandamide Exerts a Differential Effect on Human Placenta Before and After the Onset of Labor
InconclusivoEstudo LaboratorialGestação Anandamida (AEA)
2021
Are Canadian Cannabis Dispensaries Counselling Pregnant Women Appropriately?
InconclusivoMetanáliseNáusea e Vômito Gestação
2021
Association between gestational cannabis exposure and maternal, perinatal, placental, and childhood outcomes
DesfavorávelMetanáliseGestação
2021
Associations Between Prenatal Cannabis Exposure and Childhood Outcomes: Results From the ABCD Study
DesfavorávelMetanáliseGestação
2021
Can Cannabidiol Affect the Efficacy of Chemotherapy and Epigenetic Treatments in Cancer?
FavorávelMetanáliseDor Câncer Inflamação CBD Farmacêutico+6
2021
Cannabidiol disrupts apoptosis, autophagy and invasion processes of placental trophoblasts
DesfavorávelEstudo LaboratorialGestação Alterações Cerebrais Neonatais
2021
Cannabidiol loaded extracellular vesicles sensitize triple-negative breast cancer to doxorubicin in both in-vitro and in vivo models
FavorávelEstudo LaboratorialCâncer Inflamação Câncer — Mama
2021
Cannabinoid signalling and effects of cannabis on the male reproductive system
InconclusivoMetanáliseInfertilidade Masculina Libido Disfunção Erétil Endocanabinoide (não especificado)
2021
Cannabinoid Signalling in Immune-Reproductive Crosstalk during Human Pregnancy
DesfavorávelMetanáliseGestação
2021
Cannabis and Cannabinoids in Reproduction and Fertility: Where We Stand
DesfavorávelMetanáliseGestação Infertilidade Masculina
2021
Cannabis constituents interact at the drug efflux pump BCRP to markedly increase plasma cannabidiolic acid concentrations
FavorávelEstudo LaboratorialCâncer Câncer — Mama Ácido Canabidiólico (CBD-a)
2021
Cannabis Use during Pregnancy and Risk of Adverse Birth Outcomes: A Longitudinal Cohort Study
DesfavorávelMetanáliseGestação
2021
Cannabis Use in Pregnancy: A State of the Science Review
DesfavorávelMetanáliseEfeitos Adversos da Cannabis Disfunção Cognitiva Gestação+2
2021
Cannabis-related diagnosis in pregnancy and adverse maternal and infant outcomes
DesfavorávelMetanáliseGestação Alterações Cerebrais Neonatais
2021
Caryophyllene Oxide, the Active Compound Isolated from Leaves of Hymenaea courbaril L. (Fabaceae) with Antiproliferative and Apoptotic Effects on PC-3 Androgen-Independent Prostate Cancer Cell Line
FavorávelEstudo LaboratorialCâncer Câncer — Próstata
2021
Causal inference multiple imputation investigation of the impact of cannabinoids and other substances on ethnic differentials in US testicular cancer incidence
DesfavorávelMetanáliseCâncer Câncer — Testículo
2021
Desistance, Self-treatment, or Substitution: Decisions about Cannabis Use During Pregnancy
InconclusivoMetanáliseEfeitos Adversos da Cannabis Dependência — Cannabis Ansiedade+4
2021
Early life stress and development of the endocannabinoid system: A bidirectional process in programming future coping
InconclusivoMetanáliseGestação Anandamida (AEA)2-Araquidonoilglicerol (2-AG)
2021
Effect of d-limonene and its derivatives on breast cancer in human trials: a scoping review and narrative synthesis
FavorávelMetanálise ClínicaCâncer Câncer — Mama
2021
eHealth Interventions to Treat Substance Use in Pregnancy: A Systematic Review and Meta-Analysis
FavorávelMetanálise ClínicaDependência Química Efeitos Adversos da Cannabis Dependência — Cannabis+3
2021
Endocannabinoid System in Pregnancy Maintenance and Labor: A Mini-Review
InconclusivoMetanáliseGestação Endocanabinoide (não especificado)
2021
Exposure to Δ9-tetrahydrocannabinol during rat pregnancy leads to impaired cardiac dysfunction in postnatal life
DesfavorávelEstudo em AnimaisEfeitos Adversos da Cannabis Gestação
2021
Expression of the putative cannabinoid receptor GPR55 is increased in endometrial carcinoma
InconclusivoEstudo LaboratorialCâncer Câncer — Útero Lisofosfatidilinositol (LPI)
2021
Induced Fit Docking and Automated QSAR Studies Reveal the ER-α Inhibitory Activity of Cannabis sativa in Breast Cancer
FavorávelEstudo LaboratorialCâncer Câncer — Mama Canabitriol (CBT)
2021
Marijuana liberalization policies and perinatal health
InconclusivoMetanáliseGestação
2021
Marijuana use and sleep quality during pregnancy
InconclusivoEnsaio ClínicoInsônia e Distúrbios do Sono Gestação
2021
Marijuana Use during Pregnancy and Preterm Birth: A Prospective Cohort Study
FavorávelMetanáliseGestação
2021
Maternal and Fetal Pharmacokinetic Analysis of Cannabidiol during Pregnancy in Mice
InconclusivoEstudo em AnimaisGestação
2021
Maternal omega-3 intake differentially affects the endocannabinoid system in the progeny`s neocortex and hippocampus: Impact on synaptic markers
InconclusivoEstudo em AnimaisGestação Ômega-3
2021
Metabolic Consequences of Gestational Cannabinoid Exposure
DesfavorávelMetanáliseDoenças Cardiovasculares (DCV)Obesidade Diabetes Anandamida (AEA)Endocanabinoide (não especificado)+4
2021
N-arachidonoyl dopamine inhibits epithelial-mesenchymal transition of breast cancer cells through ERK signaling and decreasing the cellular cholesterol
FavorávelEstudo LaboratorialCâncer Câncer — Mama N-Araquidonoil Dopamina (NADA)
2021
Natural Products with Potential for Nonhormonal Male Contraception
FavorávelMetanáliseGestação Outros Compostos Relacionados
2021
Nurse home visiting and prenatal substance use in a socioeconomically disadvantaged population in British Columbia: analysis of prenatal secondary outcomes in an ongoing randomized controlled trial
FavorávelEnsaio Clínico Duplo-CegoGestação Alterações Cerebrais Neonatais
2021
Perceptions about cannabis use during pregnancy: a rapid best-framework qualitative synthesis
InconclusivoMetanáliseGestação
2021
Persistence of Δ-9-Tetrahydrocannabinol in Human Breast Milk
FavorávelEnsaio ClínicoGestação
2021
Prenatal Cannabinoid Exposure: Emerging Evidence of Physiological and Neuropsychiatric Abnormalities
DesfavorávelMetanáliseGestação Tetraidrocanabinol (THC)
2021
Synergistic Interactions of Cannabidiol with Chemotherapeutic Drugs in MCF7 Cells: Mode of Interaction and Proteomics Analysis of Mechanisms
FavorávelEstudo LaboratorialCâncer Câncer — Mama
2021
Tea tree oil extract causes mitochondrial superoxide production and apoptosis as an anticancer agent, promoting tumor infiltrating neutrophils cytotoxic for breast cancer to induce tumor regression
FavorávelEstudo LaboratorialCâncer Estresse Oxidativo Câncer — Mama Outros Compostos Relacionados+7
2021
Tetrahydrocannabinol and Its Major Metabolites are Not (or are poor) Substrates or Inhibitors of Human P-glycoprotein (P-gp/ABCB1) and Breast Cancer Resistance Protein (BCRP/ABCG2)
InconclusivoEstudo LaboratorialCâncer Câncer — Mama
2021
The effect of cannabis in the treatment of Hodgkin's lymphoma in a pregnant patient - extensive case report and literature review
InconclusivoMetanáliseCâncer Gestação Câncer — Linfoma
2021
The impact of cannabis use on male sexual function: A 10-year, single-center experience
FavorávelMetanáliseLibido Disfunção Erétil
2021
The impact of cannabis use on vasomotor symptoms, mood, insomnia and sexuality in perimenopausal and postmenopausal women: a systematic review
InconclusivoMetanáliseMenopausa
2021
The Impact of Early Life Exposure to Cannabis: The Role of the Endocannabinoid System
DesfavorávelMetanáliseGestação
2021
The major endocannabinoid anandamide (AEA) induces apoptosis of human granulosa cells
FavorávelEstudo LaboratorialInfertilidade Feminina Anandamida (AEA)
2021
The Nutraceutical N-Palmitoylethanolamide (PEA) Reveals Widespread Molecular Effects Unmasking New Therapeutic Targets in Murine Varicocele
FavorávelEstudo em AnimaisInfertilidade Masculina Palmitoiletanolamida (PEA)
2021
The relationship between cannabis use and IVF outcome—a cohort study
InconclusivoMetanáliseInfertilidade Feminina
2021
The role of endocannabinoids in pregnancy
InconclusivoMetanáliseGestação Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+1
2021
The sexualised use of cannabis among young sexual minority men: "I'm actually enjoying this for the first time"
FavorávelEnsaio ClínicoLibido Disfunção Erétil
2021
The Use of Cannabis and Cannabinoid-based Products by Pregnant Women: A Patent Review
FavorávelMetanáliseDor Inflamação Náusea e Vômito+2
2021
Therapeutic effects of β-caryophyllene on proliferative disorders and inflammation of the gerbil prostate
FavorávelEstudo em AnimaisCâncer Inflamação Câncer — Próstata
2021
Transcriptomic Changes and the Roles of Cannabinoid Receptors and PPARγ in Developmental Toxicities Following Exposure to Δ9-Tetrahydrocannabinol and Cannabidiol
DesfavorávelEstudo em AnimaisGestação Alterações Cerebrais Neonatais
2021
Unveiling the mechanism of action behind the anti-cancer properties of cannabinoids in ER + breast cancer cells: Impact on aromatase and steroid receptors
FavorávelEstudo LaboratorialCâncer Câncer — Mama Anandamida (AEA)Tetraidrocanabinol (THC)
2021
Use of cannabis in urological cancer patients: A review to evaluate risk for cancer development, therapeutic use, and symptom management
InconclusivoMetanáliseCâncer Câncer — Próstata Câncer — Bexiga+2
2020
A Potential Involvement of Anandamide in the Modulation of HO/NOS Systems: Women, Menopause, and “Medical Cannabinoids”
FavorávelEstudo em AnimaisDoenças Cardiovasculares (DCV)Estresse Oxidativo Menopausa Anandamida (AEA)Endocanabinoide (não especificado)
2020
A Survey Exploring the Relationship Between Cannabis Use Characteristics and Sexual Function in Men
FavorávelMetanáliseLibido Disfunção Erétil
2020
Beta-Caryophyllene Suppresses Ovarian Cancer Proliferation by Inducing Cell Cycle Arrest and Apoptosis
FavorávelEstudo LaboratorialCâncer Câncer — Ovário
2020
Cannabidiol (CBD) but not tetrahydrocannabinol (THC) dysregulate in vitro decidualization of human endometrial stromal cells by disruption of estrogen signaling
DesfavorávelEstudo LaboratorialGestação
2020
Cannabinoid as Potential Aromatase Inhibitor Through Molecular Modeling and Screening for Anti-Cancer Activity
FavorávelEstudo LaboratorialCâncer Câncer — Mama Canabitriol (CBT)
2020
Cannabinoid Combination Induces Cytoplasmic Vacuolation in MCF-7 Breast Cancer Cells
FavorávelEstudo LaboratorialCâncer Câncer — Mama Tetraidrocanabinol (THC)Canabigerol (CBG)+1
2020
Cannabinoids and Hormone Receptor-Positive Breast Cancer Treatment
FavorávelMetanáliseCâncer Câncer — Mama Anandamida (AEA)
2020
Cannabinoids and Prostate Cancer: A Systematic Review of Animal Studies
FavorávelMetanáliseCâncer Câncer — Próstata Canabinoides Sintéticos WIN-x
2020
Cannabis consumption might exert deleterious effects on sperm nuclear quality in infertile men
DesfavorávelMetanáliseInfertilidade Masculina
2020
Cannabis use during pregnancy and its relationship with fetal developmental outcomes and psychiatric disorders. A systematic review
InconclusivoMetanáliseGestação TDA e TDAH
2020
Cannabis use during pregnancy and postpartum
DesfavorávelMetanáliseGestação
2020
CBD Loaded Microparticles as a Potential Formulation to Improve Paclitaxel and Doxorubicin-Based Chemotherapy in Breast Cancer
FavorávelEstudo LaboratorialCâncer Câncer — Mama
2020
Considerations and Implications of Cannabidiol Use During Pregnancy
InconclusivoMetanáliseGestação
2020
Delta-9 THC can be detected and quantified in the semen of men who are chronic users of inhaled cannabis
InconclusivoMetanáliseInfertilidade Masculina
2020
Diacylglycerol lipase alpha in astrocytes is involved in maternal care and affective behaviors
InconclusivoEstudo em AnimaisDepressão Gestação 2-Araquidonoilglicerol (2-AG)Monoacilglicerol Lipase (MAGL)
2020
Insight of Druggable Cannabinoids Against Estrogen Receptor β in Breast Cancer
FavorávelEstudo LaboratorialCâncer Câncer — Mama
2020
Maternal cannabis use in pregnancy and child neurodevelopmental outcomes
DesfavorávelMetanáliseEfeitos Adversos da Cannabis Gestação Alterações Cerebrais Neonatais
2020
Maternal smoking and cannabis use during pregnancy and infant outcomes
InconclusivoMetanáliseGestação
2020
Medicinal Use of Cannabis in Children and Pregnant Women
FavorávelMetanáliseAnsiedade Dependência — Álcool Insônia e Distúrbios do Sono+6
2020
n-3 Polyunsaturated Fatty Acid Amides: New Avenues in the Prevention and Treatment of Breast Cancer
FavorávelMetanáliseCâncer Câncer — Mama
2020
Olfactory Exposure to β-Caryophyllene Increases Testosterone Levels in Women's Saliva
FavorávelMetanáliseLibido
2020
Perinatal THC exposure via lactation induces lasting alterations to social behavior and prefrontal cortex function in rats at adulthood
DesfavorávelEstudo em AnimaisGestação Alterações Cerebrais Neonatais
2020
PLGA Nanoparticles for the Intraperitoneal Administration of CBD in the Treatment of Ovarian Cancer: In Vitro and In Ovo Assessment
FavorávelEstudo LaboratorialCâncer Câncer — Ovário Câncer — Útero
2020
Prescribed medical cannabis in women with gynecologic malignancies: A single-institution survey-based study
FavorávelMetanáliseCâncer Câncer — Ovário Câncer — Colo do Útero+1
2020
Proapoptotic Activity of Achillea membranacea Essential Oil and Its Major Constituent 1,8-Cineole against A2780 Ovarian Cancer Cells
FavorávelEstudo LaboratorialCâncer Câncer — Ovário
2020
Synthetic cannabinoids AM-251 and AM-1241 induce cell death in prostate cancer cells
FavorávelEstudo LaboratorialCâncer Câncer — Próstata Canabinoides Sintéticos AM-x
2020
The association between cannabis use and testicular function in men: a systematic review and meta-analysis
DesfavorávelMetanáliseInfertilidade Masculina
2020
The Endocannabinoid System Alleviates Pain in a Murine Model of Cancer-Induced Bone Pain
FavorávelEstudo em AnimaisDor Câncer Câncer — Mama 2-Araquidonoilglicerol (2-AG)Monoacilglicerol Lipase (MAGL)+2
2020
The use of cannabis for Hyperemesis Gravidarum (HG)
FavorávelMetanáliseNáusea e Vômito Gestação Enjoo Matinal na Gestação
2020
Totality of the Evidence Suggests Prenatal Cannabis Exposure Does Not Lead to Cognitive Impairments: A Systematic and Critical Review
InconclusivoMetanáliseGestação
2020
Treatment With Cannabinoids as a Promising Approach for Impairing Fibroblast Activation and Prostate Cancer Progression
FavorávelEstudo LaboratorialCâncer Câncer — Próstata Canabinoides Sintéticos WIN-x
2020
β-caryophyllene improves sexual performance via modulation of crucial enzymes relevant to erectile dysfunction in rats
InconclusivoEstudo em AnimaisLibido Disfunção Erétil
2019
Adverse outcome pathway of developmental neurotoxicity resulting from prenatal exposures to cannabis contaminated with organophosphate pesticide residues
DesfavorávelMetanáliseGestação
2019
Anticancer Effects of n-3 EPA and DHA and Their Endocannabinoid Derivatives on Breast Cancer Cell Growth and Invasion
FavorávelEstudo LaboratorialCâncer Câncer — Mama Outros Compostos Relacionados
2019
Antitumor Activity of Abnormal Cannabidiol and Its Analog O-1602 in Taxol-Resistant Preclinical Models of Breast Cancer
FavorávelEstudo em AnimaisCâncer Câncer — Mama Canabinoides Sintéticos O-x Canabidiol Anormal (Abn-CBD)
2019
Association Between Self-reported Prenatal Cannabis Use and Maternal, Perinatal, and Neonatal Outcomes
DesfavorávelMetanáliseGestação
2019
Associations of first trimester co-use of tobacco and Cannabis with prenatal immune response and psychosocial well-being
InconclusivoMetanáliseGestação
2019
Beliefs and attitudes regarding prenatal marijuana use: Perspectives of pregnant women who report use
InconclusivoMetanáliseGestação
2019
Brief Commentary: Marijuana Use During Gestation and Lactation-Harmful Until Proved Safe
DesfavorávelMetanáliseGestação
2019
Cannabinoid exposure during pregnancy and its impact on immune function
DesfavorávelMetanáliseGestação
2019
Cannabinoid Receptors Signaling in the Development, Epigenetics, and Tumours of Male Germ Cells
InconclusivoMetanáliseCâncer Câncer — Testículo
2019
Cannabinoids in Breast Cancer: Differential Susceptibility According to Subtype
FavorávelMetanáliseCâncer Câncer — Mama Endocanabinoide (não especificado)
2019
Cannabis Abuse or Dependence During Pregnancy: A Population-Based Cohort Study on 12 Million Births
DesfavorávelMetanáliseGestação
2019
Cannabis and Male Fertility: A Systematic Review
DesfavorávelMetanáliseInfertilidade Masculina
2019
Cannabis and symptoms of PMS and PMDD
FavorávelMetanáliseDistúrbios Menstruais
2019
Cannabis Use in Pregnancy in British Columbia and Selected Birth Outcomes
DesfavorávelMetanáliseGestação
2019
Characterization of Cancer-Induced Nociception in a Murine Model of Breast Carcinoma
FavorávelEstudo em AnimaisDor Câncer Câncer — Mama Canabinoides Sintéticos WIN-x+3
2019
Consequences of Perinatal Cannabis Exposure
DesfavorávelEstudo em AnimaisGestação Canabinoide Sintético (não especificado)
2019
Detection of In Utero Cannabis Exposure in Umbilical Cord Tissue by a Sensitive Liquid Chromatography-Tandem Mass Spectrometry Method
InconclusivoEstudo LaboratorialGestação Canabinol (CBN)
2019
Dramatic Response to Laetrile and Cannabidiol (CBD) Oil in a Patient With Metastatic Low Grade Serous Ovarian Carcinoma
FavorávelMetanáliseCâncer Câncer — Metastático Câncer — Ovário
2019
Effects of Cannabinoids on Female Sexual Function
FavorávelMetanáliseLibido Disfunção Erétil
2019
Effects of cannabis tetrahydrocannabinol on endocannabinoid homeostasis in human placenta
DesfavorávelEstudo LaboratorialGestação
2019
Effects of Prenatal Marijuana Exposure on Neuropsychological Outcomes in Children Aged 1–11 Years: A Systematic Review
InconclusivoMetanáliseGestação
2019
Enhancing Breast Cancer Treatment Using a Combination of Cannabidiol and Gold Nanoparticles for Photodynamic Therapy
FavorávelMetanáliseCâncer Câncer — Mama
2019
Future Aspects for Cannabinoids in Breast Cancer Therapy
FavorávelMetanáliseCâncer Câncer — Mama Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+12
2019
How Cannabis Alters Sexual Experience: A Survey of Men and Women
FavorávelMetanáliseLibido Disfunção Erétil
2019
Interaction of maternal choline levels and prenatal Marijuana's effects on the offspring
DesfavorávelMetanáliseGestação
2019
Marijuana smoking and markers of testicular function among men from a fertility centre
FavorávelMetanáliseInfertilidade Masculina
2019
Marijuana Use in Pregnancy: A Review
DesfavorávelMetanáliseGestação
2019
Marijuana use in young mothers and adverse pregnancy outcomes: a retrospective cohort study
DesfavorávelMetanáliseGestação
2019
Marijuana-derived cannabinoids inhibit uterine endometrial stromal cell decidualization and compromise trophoblast-endometrium cross-talk
DesfavorávelEstudo LaboratorialGestação Canabinol (CBN)
2019
Monitoring the effects of perinatal cannabis and synthetic cannabinoid exposure
DesfavorávelMetanáliseGestação
2019
Plasma anandamide and related n-acylethanolamide levels are not elevated in pregnancies complicated by hyperemesis gravidarum
InconclusivoEnsaio ClínicoNáusea e Vômito Gestação Enjoo Matinal na Gestação Anandamida (AEA)Outros Compostos Relacionados
2019
Preconception and prenatal cannabis use and the risk of behavioural and emotional problems in the offspring; a multi-informant prospective longitudinal study
DesfavorávelMetanáliseGestação
2019
Prenatal drug exposure and neurodevelopmental programming of glucocorticoid signalling
InconclusivoMetanáliseGestação
2019
Prenatal THC exposure produces a hyperdopaminergic phenotype rescued by pregnenolone
DesfavorávelEstudo em AnimaisGestação
2019
Prevalence and predictors of cannabis use among men receiving androgen-deprivation therapy for advanced prostate cancer
FavorávelEnsaio ClínicoCâncer Câncer — Próstata
2019
Routes of cannabis administration among females in the year before and during pregnancy: Results from a pilot project
InconclusivoMetanáliseGestação
2019
Self-reported Daily, Weekly, and Monthly Cannabis Use Among Women Before and During Pregnancy
InconclusivoMetanáliseGestação
2019
Sex-specific behavioral deficits induced at early life by prenatal exposure to the cannabinoid receptor agonist WIN 55,212-2 depend on mGlu5 receptor signaling
InconclusivoEstudo em AnimaisGestação Canabinoides Sintéticos WIN-x
2019
Systematic review of the potential role of cannabinoids as antiproliferative agents for urological cancers
InconclusivoMetanáliseCâncer Câncer — Mama Câncer — Cérebro 2-Araquidonoilglicerol (2-AG)+4
2019
The onus of cannabinoids in interrupting the molecular odyssey of breast cancer: A critical perspective on UPRER and beyond
FavorávelMetanáliseCâncer Câncer — Mama Endocanabinoide (não especificado)Canabinoide Sintético (não especificado)+1
2019
The Relationship between Cannabis and Male Infertility, Sexual Health, and Neoplasm: a Systematic Review
InconclusivoMetanáliseCâncer Câncer — Próstata Infertilidade Masculina+4
2019
The Relationship between Marijuana Use Prior to Sex and Sexual Function in Women
FavorávelMetanáliseLibido Disfunção Erétil
2019
The Role of Acculturation and Alcohol Problems on Frequency of Cannabis Use Among Latinas at Risk of an Alcohol-Exposed Pregnancy
DesfavorávelEnsaio ClínicoDependência Química Efeitos Adversos da Cannabis Dependência — Cannabis+2
2019
The role of the endocannabinoid system in female reproductive tissues
FavorávelMetanáliseCâncer Câncer — Ovário Endocanabinoide (não especificado)
2019
Therapeutic targeting of HER2–CB2R heteromers in HER2-positive breast cancer
FavorávelEstudo em AnimaisCâncer Câncer — Mama
2019
Towards the use of non-psychoactive cannabinoids for prostate cancer
FavorávelMetanáliseCâncer Câncer — Próstata
2019
Trends and correlates of cannabis use in pregnancy: a population-based study in Ontario, Canada from 2012 to 2017
DesfavorávelMetanáliseGestação
2019
Women's perspectives about cannabis use during pregnancy and the postpartum period: An integrative review
InconclusivoMetanáliseGestação
2019
α-Pinene Induces Apoptotic Cell Death via Caspase Activation in Human Ovarian Cancer Cells
FavorávelEstudo LaboratorialCâncer Câncer — Ovário
2019
Δ9-Tetrahydrocannabinol leads to endoplasmic reticulum stress and mitochondrial dysfunction in human BeWo trophoblasts
DesfavorávelEstudo LaboratorialGestação
2018
A prospective and longitudinal study of plasma phospholipid saturated fatty acid profile in relation to cardiometabolic biomarkers and the risk of gestational diabetes
FavorávelMetanáliseDiabetes Síndrome Metabólica Gestação Ácido Pentadecanoico (C15:0)
2018
An epidemiological, developmental and clinical overview of cannabis use during pregnancy
InconclusivoMetanáliseGestação
2018
Anti-invasion Effects of Cannabinoids Agonist and Antagonist on Human Breast Cancer Stem Cells
FavorávelEstudo LaboratorialCâncer Câncer — Mama Canabinoides Sintéticos AM-x
2018
Appraising the "Entourage Effect": Antitumor Action of a Pure Cannabinoid Versus a Botanical Drug Preparation in Preclinical Models of Breast Cancer
FavorávelEstudo em AnimaisCâncer Câncer — Mama THC Farmacêutico
2018
Association between use of marijuana and time to pregnancy in men and women: findings from the National Survey of Family Growth
InconclusivoMetanáliseInfertilidade Masculina
2018
C-Phycocyanin exerts anti-cancer effects via the MAPK signaling pathway in MDA-MB-231 cells
FavorávelEstudo LaboratorialCâncer Câncer — Mama Ficocianina
2018
Cannabinoid-induced Cell Death In Endometrial Cancer Cells: Involvement Of TRPV1 Receptors In Apoptosis
FavorávelEstudo LaboratorialCâncer Câncer — Útero Anandamida (AEA)2-Araquidonoilglicerol (2-AG)
2018
Cannabis Use During the Perinatal Period in a State With Legalized Recreational and Medical Marijuana: The Association Between Maternal Characteristics, Breastfeeding Patterns, and Neonatal Outcomes
DesfavorávelMetanáliseGestação
2018
Chronic cannabidiol exposure promotes functional impairment in sexual behavior and fertility of male mice.
DesfavorávelEstudo em AnimaisLibido Disfunção Erétil
2018
Combined CB2 receptor agonist and photodynamic therapy synergistically inhibit tumor growth in triple negative breast cancer
FavorávelEstudo LaboratorialCâncer Câncer — Mama
2018
Data Are Needed on the Potential Adverse Effects of Marijuana Use in Pregnancy
InconclusivoMetanáliseGestação
2018
Effects of Δ(9)-tetrahydrocannabinol (THC) on human amniotic epithelial cell proliferation and migration
DesfavorávelEstudo em AnimaisGestação
2018
Marijuana use differentially affects cannabinoid receptor expression in early gestational human endometrium and placenta.
InconclusivoEstudo LaboratorialGestação Endocanabinoide (não especificado)
2018
Marijuana Use in Pregnancy and While Breastfeeding
DesfavorávelMetanáliseGestação
2018
Maternal administration of cannabidiol promotes an anti-inflammatory effect on the intestinal wall in a gastroschisis rat model
FavorávelEstudo em AnimaisCâncer Inflamação Estresse Oxidativo+9
2018
Maternal and paternal cannabis use during pregnancy and the risk of psychotic-like experiences in the offspring
DesfavorávelMetanálisePsicose Gestação
2018
Medicinal Cannabis in Pregnancy - Panacea or Noxious Weed?
DesfavorávelMetanáliseGestação
2018
Melatonin attenuates Δ 9-tetrahydrocannabinol-induced reduction in rat sperm motility and kinematics in-vitro
FavorávelEstudo em AnimaisInfertilidade Masculina Tetraidrocanabinol (THC)
2018
RhoA/MLC signaling pathway is involved in Δ⁹-tetrahydrocannabinol-impaired placental angiogenesis
DesfavorávelEstudo em AnimaisGestação Tetraidrocanabinol (THC)
2018
Sex-dependent effects of in utero cannabinoid exposure on cortical function
InconclusivoEstudo em AnimaisGestação Alterações Cerebrais Neonatais Anandamida (AEA)Tetraidrocanabinol (THC)+1
2018
The LPI/GPR55 axis enhances human breast cancer cell migration via HBXIP and p-MLC signaling
DesfavorávelEstudo em AnimaisCâncer Câncer — Mama Lisofosfatidilinositol (LPI)
2018
Transfer of Inhaled Cannabis Into Human Breast Milk
DesfavorávelMetanáliseGestação Tetraidrocanabinol (THC)
2018
α-Pinene Inhibits Human Prostate Cancer Growth in a Mouse Xenograft Model
FavorávelEstudo em AnimaisCâncer Câncer — Próstata
2017
Association Between Marijuana Use and Sexual Frequency in the United States: A Population-Based Study
FavorávelMetanáliseLibido Disfunção Erétil
2017
Cannabidiolic Acid-mediated Selective Down-regulation Of C-fos In Highly Aggressive Breast Cancer MDA-MB-231 Cells: Possible Involvement Of Its Down-regulation In The Abrogation Of Aggressiveness
FavorávelEstudo LaboratorialCâncer Câncer — Mama Ácido Canabidiólico (CBD-a)
2017
Cannabis use and incidence of testicular cancer: a 42-year follow-up of Swedish men between 1970 and 2011
DesfavorávelMetanáliseCâncer Câncer — Testículo
2017
Endocannabinoid system in sexual motivational processes: Is it a novel therapeutic horizon?
FavorávelMetanáliseLibido Disfunção Erétil Anandamida (AEA)Tetraidrocanabinol (THC)+3
2017
Individual prolactin reactivity modulates response of nucleus accumbens to erotic stimuli during acute cannabis intoxication: an fMRI pilot study
FavorávelEnsaio ClínicoLibido Disfunção Erétil
2017
Masturbation to Orgasm Stimulates the Release of the Endocannabinoid 2-Arachidonoylglycerol in Humans.
FavorávelEnsaio Clínico Duplo-CegoLibido Disfunção Erétil Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+1
2017
Newborn birth-weight of pregnant women on methadone or buprenorphine maintenance treatment: A national contingency management approach trial
InconclusivoEnsaio ClínicoDependência Química Dependência — Cannabis Depressão+6
2017
Polyunsaturated Fatty Acids Differentially Modulate Cell Proliferation and Endocannabinoid System in Two Human Cancer Lines
FavorávelEstudo LaboratorialCâncer Câncer — Mama Câncer — Cérebro Ômega-3 Ômega-6
2016
Activation of the orphan receptor GPR55 by lysophosphatidylinositol promotes metastasis in triple-negative breast cancer
FavorávelMetanáliseCâncer Câncer — Mama Câncer — Metastático Lisofosfatidilinositol (LPI)
2016
Cannabidiol Rather Than Cannabis Sativa Extracts Inhibit Cell Growth And Induce Apoptosis In Cervical Cancer Cells
FavorávelEstudo LaboratorialCâncer Câncer — Colo do Útero
2016
Characterization of non-olfactory GPCRs in human sperm with a focus on GPR18.
FavorávelEstudo LaboratorialInfertilidade Masculina Outros Compostos Relacionados
2016
Expectancy mediated effects of marijuana on menopause symptoms
FavorávelMetanáliseMenopausa
2016
Fetal Syndrome of Endocannabinoid Deficiency (FSECD) In Maternal Obesity
InconclusivoMetanáliseObesidade Gestação
2016
Geraniol Suppresses Prostate Cancer Growth Through Down-Regulation of E2F8
FavorávelEstudo LaboratorialCâncer Câncer — Próstata
2016
Maternal Marijuana Use and Adverse Neonatal Outcomes: A Systematic Review and Meta-analysis.
InconclusivoMetanáliseGestação
2016
Melatonin and vitamin C exacerbate Cannabis sativa-induced testicular damage when administered separately but ameliorate it when combined in rats
InconclusivoEstudo em AnimaisInfertilidade Masculina
2016
Phyto-, endo- and synthetic cannabinoids: promising chemotherapeutic agents in the treatment of breast and prostate carcinomas.
FavorávelMetanáliseCâncer Câncer — Mama Câncer — Próstata Endocanabinoide (não especificado)Canabinoide Sintético (não especificado)
2016
Prevalence and correlates of a lifetime cannabis use disorder among pregnant former tobacco smokers
FavorávelMetanáliseDependência Química Efeitos Adversos da Cannabis Dependência — Cannabis+1
2016
Type 2 cannabinoid receptor contributes to the physiological regulation of spermatogenesis.
FavorávelEstudo LaboratorialInfertilidade Masculina Canabinoides Sintéticos JWH-x
2015
Anti-invasive effect of β-myrcene, a component of the essential oil from Pinus koraiensis cones, in metastatic MDA-MB-231 human breast cancer cells
FavorávelEstudo LaboratorialCâncer Câncer — Mama
2015
Anticancer activity of Cinnamon tamala leaf constituents towards human ovarian cancer cells.
FavorávelEstudo LaboratorialCâncer Câncer — Ovário
2015
Cannabis exposure and risk of testicular cancer: a systematic review and meta-analysis
DesfavorávelMetanáliseCâncer Câncer — Testículo
2015
Endocannabinoid Levels in Newborns in Relation to the Mode of Delivery.
FavorávelEnsaio ClínicoGestação Trabalho de Parto e Complicações Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+1
2015
Invited Commentary: The Association Between Marijuana Use and Male Reproductive Health
DesfavorávelMetanáliseInfertilidade Masculina
2015
Marijuana, phytocannabinoids, the endocannabinoid system, and male fertility
DesfavorávelMetanáliseInfertilidade Masculina
2015
Modulation of the tumor microenvironment and inhibition of EGF/EGFR pathway; novel anti-tumor mechanisms of Cannabidiol in breast cancer
FavorávelEstudo em AnimaisCâncer Câncer — Mama
2015
Molecular mechanism of anti-cancer activity of phycocyanin in triple-negative breast cancer cells
FavorávelEstudo LaboratorialCâncer Câncer — Mama Ficocianina
2015
New horizons for newborn brain protection: enhancing endogenous neuroprotection
FavorávelMetanáliseTrabalho de Parto e Complicações Canabinoides Sintéticos WIN-x Canabinoides Sintéticos HU-x
2015
Proapoptotic effect of endocannabinoids in prostate cancer cells
FavorávelEstudo LaboratorialCâncer Câncer — Próstata Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+2
2015
Selective, nontoxic CB(2) cannabinoid o-quinone with in vivo activity against triple-negative breast cancer.
FavorávelEstudo em AnimaisCâncer Câncer — Mama
2014
Cannabinoid Receptor Type 1 Immunoreactivity and Disease Severity in Human Epithelial Ovarian Tumors
FavorávelEstudo LaboratorialCâncer Câncer — Ovário
2014
Cannabis use during pregnancy in France in 2010
DesfavorávelMetanáliseGestação Trabalho de Parto e Complicações
2014
Effectiveness of the Association N-Palmitoylethanolamine and Transpolydatin in the Treatment of Primary Dysmenorrhea
FavorávelEnsaio ClínicoDor — Aguda Gestação Dor — Oncológica Palmitoiletanolamida (PEA)+1
2014
Marijuana Use and Maternal Experiences of Severe Nausea During Pregnancy in Hawai‘i
DesfavorávelMetanáliseNáusea e Vômito Gestação Enjoo Matinal na Gestação
2014
Plasma metabolomic profiles of breast cancer patients after short-term limonene intervention.
FavorávelEstudo LaboratorialCâncer Câncer — Mama
2014
Potential first trimester metabolomic biomarkers of abnormal birth weight in healthy pregnancies
FavorávelEnsaio ClínicoDiabetes Síndrome Metabólica Gestação Proteína Ligadora de Ácidos Graxos (FABP)
2014
Relationship between seminal plasma levels of anandamide congeners palmitoylethanolamide and oleoylethanolamide and semen quality
DesfavorávelMetanáliseInfertilidade Masculina
2014
Targeting Multiple Cannabinoid Anti-tumour Pathways With A Resorcinol Derivative Leads To Inhibition Of Advanced Stages Of Breast Cancer
FavorávelEstudo em AnimaisCâncer Câncer — Mama Câncer — Metastático Canabinoides Sintéticos O-x
2013
Cannabinoids: Well-Suited Candidates for the Treatment of Perinatal Brain Injury.
FavorávelMetanáliseEstresse Oxidativo Doenças Neurodegenerativas AVC Canabinoides Sintéticos WIN-x+2
2013
Elevated anandamide and related N-acylethanolamine levels occur in the peripheral blood of women with ectopic pregnancy and are mirrored by changes in peripheral fatty acid amide hydrolase activity
InconclusivoMetanáliseGestação Anandamida (AEA)Hidrolase de Amidas de Ácidos Graxos (FAAH)+2
2013
Human breast tissue disposition and bioactivity of limonene in women with early stage breast cancer.
FavorávelEnsaio ClínicoCâncer Câncer — Mama
2013
Illicit drug use among pregnant women enrolled in treatment for cigarette smoking cessation
DesfavorávelEnsaio ClínicoDependência Química Dependência — Cannabis Dependência — Opioides+5
2013
Non-THC Cannabinoids Inhibit Prostate Carcinoma Growth In Vitro And In Vivo: Pro-apoptotic Effects And Underlying Mechanisms
FavorávelEstudo em AnimaisCâncer Câncer — Próstata Canabigerol (CBG)Canabinol (CBN)+5
2013
Physical and Psychologic Effects of Aromatherapy Inhalation on Pregnant Women: A Randomized Controlled Trial
InconclusivoEnsaio Clínico Duplo-CegoGestação
2012
Cannabidiolic acid, a major cannabinoid in fiber-type cannabis, is an inhibitor of MDA-MB-231 breast cancer cell migration.
FavorávelEstudo LaboratorialCâncer Câncer — Mama Ácido Canabidiólico (CBD-a)
2012
Pain relief assessment by aromatic essential oil massage on outpatients with primary dysmenorrhea: a randomized, double-blind clinical trial.
FavorávelEnsaio Clínico Duplo-CegoDistúrbios Menstruais
2012
The role of cannabinoids in prostate cancer: Basic science perspective and potential clinical applications
FavorávelMetanáliseCâncer Câncer — Próstata Canabinoides Sintéticos WIN-x Canabinoides Sintéticos SR-x
2011
Buprenorphine versus methadone in pregnant opioid-dependent women: a prospective multicenter study
InconclusivoEnsaio ClínicoDependência Química Efeitos Adversos da Cannabis Dependência — Cannabis+4
2011
Cannabinoid as a neuroprotective strategy in perinatal hypoxic-ischemic injury
InconclusivoMetanáliseGestação Trabalho de Parto e Complicações
2011
Marijuana use and testicular germ cell tumors
DesfavorávelMetanáliseCâncer Câncer — Testículo
2011
Marijuana Use is Not Associated with Cervical Human Papillomavirus Natural History or Cervical Neoplasia in HIV-seropositive or HIV-seronegative Women
InconclusivoMetanáliseCâncer Câncer — Colo do Útero
2011
Pathways Mediating The Effects Of Cannabidiol On The Reduction Of Breast Cancer Cell Proliferation, Invasion, And Metastasis
FavorávelEstudo em AnimaisCâncer Câncer — Mama Câncer — Pulmão
2011
The manifold actions of endocannabinoids on female and male reproductive events
InconclusivoMetanáliseInfertilidade Masculina Endocanabinoide (não especificado)
2010
Cannabidiol Inhibits Cancer Cell Invasion Via Upregulation Of Tissue Inhibitor Of Matrix Metalloproteinases-1
FavorávelEstudo em AnimaisCâncer Câncer — Pulmão Câncer — Metastático+1
2010
Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition
FavorávelEstudo em AnimaisCâncer Câncer — Mama Tetraidrocanabinol (THC)Canabinoides Sintéticos JWH-x
2010
Characteristics of pregnant illicit drug users and associations between cannabis use and perinatal outcome in a population-based study
InconclusivoMetanáliseGestação Trabalho de Parto e Complicações
2009
Increased Expressions Of Cannabinoid Receptor-1 And Transient Receptor Potential Vanilloid-1 In Human Prostate Carcinoma
FavorávelEstudo LaboratorialCâncer Câncer — Próstata
2009
R(+)-methanandamide-induced apoptosis of human cervical carcinoma cells involves a cyclooxygenase-2-dependent pathway
FavorávelEstudo LaboratorialCâncer Câncer — Colo do Útero Outros Compostos Relacionados
2009
Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer
FavorávelEstudo em AnimaisCâncer Câncer — Mama Câncer — Metastático Canabinoides Sintéticos AM-x Canabinoides Sintéticos WIN-x+2
2009
The endocannabinoid system during development: emphasis on perinatal events and delayed effects
InconclusivoMetanáliseGestação 2-Araquidonoilglicerol (2-AG)
2009
Treatment of a hyperkinetic movement disorder during pregnancy with dronabinol.
FavorávelMetanáliseDoença de Parkinson Gestação Tetraidrocanabinol (THC)THC Farmacêutico
2008
CB2 receptors in reproduction
FavorávelMetanáliseGestação Infertilidade Masculina Infertilidade Feminina Anandamida (AEA)2-Araquidonoilglicerol (2-AG)
2008
Early endothelial dysfunction as a marker of vasculogenic erectile dysfunction in young habitual cannabis users
DesfavorávelMetanáliseLibido Disfunção Erétil
2008
Effects of perinatal exposure to delta-9-tetrahydrocannabinol on the emotional reactivity of the offspring: a longitudinal behavioral study in Wistar rats
DesfavorávelEstudo em AnimaisGestação Transtornos de Comportamento Tetraidrocanabinol (THC)
2008
JunD Is Involved In The Antiproliferative Effect Of Δ9-tetrahydrocannabinol On Human Breast Cancer Cells
FavorávelEstudo LaboratorialCâncer Câncer — Mama
2008
Linalool, a plant-derived monoterpene alcohol, reverses doxorubicin resistance in human breast adenocarcinoma cells.
FavorávelEstudo LaboratorialCâncer Câncer — Mama
2008
The influence of mast cell mediators on migration of SW756 cervical carcinoma cells
FavorávelEstudo LaboratorialCâncer Câncer — Colo do Útero 2-Araquidonoilglicerol (2-AG)Canabinoides Sintéticos WIN-x
2007
Cannabidiol As A Novel Inhibitor Of Id-1 Gene Expression In Aggressive Breast Cancer Cells
FavorávelEstudo LaboratorialCâncer Câncer — Mama
2007
Endocannabinoid Hedonic Hotspot for Sensory Pleasure: Anandamide in Nucleus Accumbens Shell Enhances ‘Liking’ of a Sweet Reward.
FavorávelEstudo em AnimaisLibido Disfunção Erétil Anandamida (AEA)
2007
Potentiating Effect Of Beta-caryophyllene On Anticancer Activity Of Alpha-humulene, Isocaryophyllene And Paclitaxel
FavorávelEstudo LaboratorialCâncer Câncer — Mama
2006
Anti-tumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma
FavorávelEstudo em AnimaisCâncer Câncer — Mama Câncer — Pulmão Tetraidrocanabinol (THC)Canabigerol (CBG)+3

Perguntas frequentes

Quantos estudos sobre sistema reprodutor estão indexados no acervo?

São 341 estudos, publicados entre 1847 e 2024. O acervo inteiro tem 7.640 registros.

Que tipos de estudo predominam?

Metanálise: 161 · Estudo Laboratorial: 84 · Estudo em Animais: 66 · Ensaio Clínico: 21 · Ensaio Clínico Duplo-Cego: 6 · Metanálise Clínica: 3. A classificação segue o desenho declarado na fonte.

O que significa a classificação de resultado?

É uma leitura automatizada da conclusão de cada estudo, em três direções — favorável, inconclusivo e desfavorável. Aqui são 166 favoráveis, 73 inconclusivos e 102 desfavoráveis. Serve para navegar o acervo, não para concluir nada clinicamente: a conclusão válida é a do artigo original.

Como citar esta página

ABNT

CANNABIS INDICA. Sistema Reprodutor — estudos científicos sobre cannabis. 2026. Disponível em: https://cannabisindica.com.br/sistema/sistema-reprodutor/. Acesso em: 13 set. 2026.

APA

Cannabis Indica. (2026). Sistema Reprodutor — estudos científicos sobre cannabis. https://cannabisindica.com.br/sistema/sistema-reprodutor/

Esta página é um índice de acesso. Ao usar um estudo como evidência, cite o artigo original — o link de cada registro leva à fonte.